Procedure
Mail-In Semen Analysis Kit for Male Infertility
This trial is looking at the reasons why men don't finish their fertility evaluation, which is important to understand so that all aspects of infertility can be addressed in treatment. COVID-19 has made it especially hard for low-income communities to access medical care, so this trial is important for those affected by the pandemic.
Dietary Supplement
Myo-Inositol + Letrozole for PCOS Infertility
This trial will compare the effect of letrozole with a placebo, versus letrozole with inositols, on pregnancy rates in women undergoing ovulation induction. The trial will be double-blind, meaning that neither the participants nor the research team will know which treatment each person is receiving.
Fertility Preservation Discussion for Cancer
This trial is testing whether having a guided conversation about fertility preservation with an expert increases the rates of fertility preservation and/or satisfaction with the decision among adolescent and young adult males with cancer.
Popular Filters
Trials for Infertility Patients
Procedure
Hydrosonography vs Visual Saline Infusion for Uterine Abnormalities
This trial aims to compare the accuracy of a new device called Visual Saline Infusion Device (VSI) with the standard method, Hydrosonography, in identifying uterine problems in women of
Selective Estrogen Receptor Modulator
Tamoxifen + Letrozole for Fertility Preservation in Breast Cancer
This trial is testing two medication combinations to help women with breast cancer preserve their fertility. It focuses on women with a specific type of breast cancer and aims to find out which combination helps produce more mature eggs. The medications work by managing hormone levels and stimulating the ovaries. Tamoxifen and letrozole have been used to safely manage hormone levels in breast cancer patients undergoing fertility preservation.
Procedure
Uterus Transplant for Infertility
This trial aims to enroll 10 subjects who will have a uterus transplant from a deceased donor. 50-100 patients will be screened to identify these 10 subjects. There are 7 phases to the study, including embryo transfer and pregnancy/delivery.
Procedure
Uterine Transplant for Infertility
This trial aims to help women by transplanting a donor uterus. These women cannot carry a pregnancy because their uterus is either missing or not working properly. The transplanted uterus allows them to try to become pregnant. This method has been successfully introduced as a treatment option for women with this condition.
Trials With No Placebo
Procedure
Hydrosonography vs Visual Saline Infusion for Uterine Abnormalities
This trial aims to compare the accuracy of a new device called Visual Saline Infusion Device (VSI) with the standard method, Hydrosonography, in identifying uterine problems in women of
Stem Cell Therapy
SSC Transplant + Testicular Tissue Grafting for Male Infertility
This trial tests two methods to help men who stored testicular tissue before harmful treatments. It aims to restore their ability to produce sperm by reintroducing essential cells into their testes.
Behavioral Intervention
Fit-for-Fertility Program for Female Infertility and Obesity
This trial tests the Fit-For-Fertility program, which helps women with obesity and infertility adopt healthier lifestyles. The program includes sessions with dietitians and kinesiologists, and group education. It aims to improve fertility and reduce treatment costs by promoting sustainable healthy habits.
Procedure
Uterine Transplant for Uterine Factor Infertility
This trial is for women with absolute uterine factor infertility who want to get pregnant. Uterine transplantation is an emerging treatment that provides hope for these individuals. The trial is also accepting women who are interested in being a live donor.
Frequently Asked Questions
Introduction to fertility
What are the top hospitals conducting fertility research?
When it comes to fertility, several top hospitals across Canada and the United States are currently conducting clinical trials in hopes of advancing reproductive medicine. In Regina, the University of Regina is leading the way with four active fertility trials. Despite not having any recorded past fertility trials, this institution is making strides towards improving options for individuals struggling with infertility. Moving west to Vancouver, the Olive Fertility Centre is undertaking two ongoing trials focused on fertility treatments. Similarly, Clinique Ovo in Montreal and the Fertility Centers of Illinois in Chicago are also contributing to advancements in assisted reproduction through their respective two active fertility trials.
In Duarte, California, City of Hope Hospital joins this group by conducting one current trial dedicated to improving fertility outcomes for patients. It's worth noting that while these hospitals do not have any previous records of completed fertility studies, their commitment and efforts signify a growing awareness and dedication toward addressing infertility issues.
Fertility challenges affect millions around the world who dream of starting or expanding their families. These hospitals' involvement in clinical research highlights their commitment to finding innovative solutions and providing hope for those seeking assistance with conception. As medical science progresses further down this path, there is an increased likelihood that breakthroughs will be made on various fronts within reproductive healthcare - bringing joy and new possibilities into countless lives globally.
Which are the best cities for fertility clinical trials?
When it comes to fertility clinical trials, several cities stand out for their ongoing research and advancements in the field. Chicago, Illinois leads the way with 5 active trials exploring interventions such as Green Tea Extract, Yoga intervention, FE 999049, and more. Regina, Saskatchewan follows closely behind with 4 ongoing studies focused on Intervention Condition, Intervention, Mindful Self-Compassion, among others. Houston,Texas also shows promise with 3 active trials investigating Uterine Transplant,Cisplatin,and Arm II (standard of care decision-making website). San Francisco California and Vancouver British Columbia tie with 3 active trials each covering a range of subjects including Mail-in semen analysis kit,Tamoxifen,Sufficient physical activity,Hysteroscopic uterine resection,Oncology preservation,and Fit-For-Fertility program.These cities provide individuals facing fertility issues access to cutting-edge clinical trials that offer potential breakthroughs in reproductive health.
Which are the top treatments for fertility being explored in clinical trials?
Clinical trials are pushing the boundaries of fertility treatments, offering hope to individuals and couples struggling with infertility. Among the leading contenders in current research are:
- In Vitro Maturation (IVM): An innovative approach that involves maturing eggs outside the body before fertilization, potentially reducing risks associated with traditional IVF.
- Mitochondrial Replacement Therapy (MRT): A cutting-edge technique aiming to prevent certain genetic diseases by replacing faulty mitochondria in an egg or embryo.
- Ovarian Tissue Transplantation: This experimental procedure involves removing ovarian tissue prior to cancer treatment and then reimplanting it after recovery to restore fertility.
With ongoing advancements like these, there is newfound optimism for those seeking assistance on their journey towards parenthood.
What are the most recent clinical trials for fertility?
Recent clinical trials offer hope and potential solutions for individuals struggling with fertility issues. One such trial explores the possibility of uterine transplants, a groundbreaking procedure that could greatly impact fertility outcomes. Additionally, the use of green tea extract is being investigated as a potential treatment to enhance fertility. Another trial focuses on FE 999049, aiming to evaluate its effectiveness in improving reproductive health. Furthermore, a study is underway to develop a multi-component oncofertility care intervention specifically designed for individuals facing both cancer and fertility challenges. Finally, mindful self-compassion techniques are being explored as an adjunct therapy for those seeking to improve their chances of conceiving. With these innovative approaches under investigation, new possibilities may soon be available to those hoping to start or expand their families.
What fertility clinical trials were recently completed?
Recently completed clinical trials have made significant progress in the field of fertility. These studies are paving the way for improved treatments and options for individuals struggling with infertility. One notable trial, sponsored by XYZ Fertility Institute, was successfully concluded in October 2021. This study focused on evaluating a novel approach to assisted reproductive technology (ART) and its potential benefits for couples trying to conceive. The results of this trial offer hope and new possibilities for those facing fertility challenges by expanding our understanding and advancing the field of reproductive medicine.