Psilocybin for Depression and Alcoholism
Recruiting0 awardsPhase 2
Baltimore, Maryland
This trial is testing if psilocybin can help people with both depression and alcohol problems. The drug might improve mood and reduce drinking by changing brain activity. The study involves giving psilocybin to see if it helps. Psilocybin is a naturally occurring psychedelic that has shown promise in treating mood and substance use disorders.
Hormone Therapy
Oxytocin + COPE Therapy for Alcoholism and PTSD
Recruiting0 awardsPhase 2
Charleston, South Carolina
This trial will compare oxytocin to a placebo in reducing symptoms of alcohol use disorder and post-traumatic stress disorder in veterans receiving COPE therapy. Brain scans will be used to examine potential mechanisms of change.
Serotonin/Dopamine Activity Modulator
Brexpiprazole for Alcoholism
Recruiting1 awardPhase 2
Aurora, Colorado
This trial tests whether brexpiprazole can help reduce alcohol consumption in people with Alcohol Use Disorder who are not seeking treatment. The medication works by balancing brain chemicals related to mood and behavior. Researchers will also see if genetic differences affect how well the medication works. Brexpiprazole is a newer medication related to aripiprazole, which has shown potential in reducing alcohol use by stabilizing dopamine and serotonin systems.
Popular Filters
Trials for Alcohol Use Disorder Patients
NMDA Receptor Antagonist
Ketamine for Treatment-Resistant Depression
Recruiting1 awardPhase 2
Iowa City, Iowa
This trial is testing whether the antidepressant effects of ketamine are greater in people with a family history of alcohol use disorder, who may respond differently to both alcohol and ketamine.
Alcohol Effects on Drinking Behavior
Recruiting0 awards5 criteria
Chicago, Illinois
This trial looks at how different people react to alcohol and other substances, and whether this predicts how much they will drink in the future. It also looks at how people's responses to alcohol change if their drinking habits do.
Behavioural Intervention
Parent-Child Assistance Program for Substance Use During Pregnancy
Recruiting1 award
Oklahoma City, Oklahoma
This trial helps 200 mothers in Oklahoma who use alcohol/drugs during pregnancy & their children by providing support/resources for 3 years. Benefits include substance use disorder treatment, birth control, abstinence, child custody, & criminal justice involvement.
Trials for AUD Patients
NMDA Receptor Antagonist
Ketamine for Treatment-Resistant Depression
Recruiting1 awardPhase 2
Iowa City, Iowa
This trial is testing whether the antidepressant effects of ketamine are greater in people with a family history of alcohol use disorder, who may respond differently to both alcohol and ketamine.
Alcohol Effects on Drinking Behavior
Recruiting0 awards5 criteria
Chicago, Illinois
This trial looks at how different people react to alcohol and other substances, and whether this predicts how much they will drink in the future. It also looks at how people's responses to alcohol change if their drinking habits do.
Behavioural Intervention
Psycho-education & Understanding Bipolar Medications Therapy + MBSR + ISRT + Bipolar-Specific CBT for Bipolar Disorder
Recruiting1 award
Atlanta, Georgia
This trial will study how to better treat bipolar patients who are suicidal by looking at environmental and psychological factors, as well as implementing a 6-week intervention program.
Trials With No Placebo
NMDA Receptor Antagonist
Ketamine for Treatment-Resistant Depression
Recruiting1 awardPhase 2
Iowa City, Iowa
This trial is testing whether the antidepressant effects of ketamine are greater in people with a family history of alcohol use disorder, who may respond differently to both alcohol and ketamine.
Behavioural Intervention
Parent-Child Assistance Program for Substance Use During Pregnancy
Recruiting1 award
Oklahoma City, Oklahoma
This trial helps 200 mothers in Oklahoma who use alcohol/drugs during pregnancy & their children by providing support/resources for 3 years. Benefits include substance use disorder treatment, birth control, abstinence, child custody, & criminal justice involvement.
Behavioural Intervention
Neural and Hormonal Influences on Alcohol Use Disorder Risk
Recruiting3 awards5 criteria
Lexington, Kentucky
This trial is looking at the neural and hormonal factors that contribute to why women are more at risk for AUD than men. They will be looking at three addiction domains: inhibitory control (executive function), negative emotionality, and alcohol cue reactivity (incentive salience).
Behavioural Intervention
Psycho-education & Understanding Bipolar Medications Therapy + MBSR + ISRT + Bipolar-Specific CBT for Bipolar Disorder
Recruiting1 award
Atlanta, Georgia
This trial will study how to better treat bipolar patients who are suicidal by looking at environmental and psychological factors, as well as implementing a 6-week intervention program.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.