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Trials for Alzheimer's Disease Patients
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
Recruiting1 award5 criteria
Westport, Connecticut
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Behavioural Intervention
Dysphagia Therapy for Alzheimer's Disease
Recruiting1 award
Madison, Wisconsin
This trial tests a saliva gel and tongue exercises to help people with Alzheimer's who have trouble swallowing. These patients are at risk of pneumonia because they can't swallow well. The saliva gel keeps their mouth moist, and the exercises make their tongue stronger to help with swallowing.
Ultrasound Therapy
ExAblate BBB Disruption for Alzheimer's Disease
Recruiting1 award5 criteria
New York, New York
This trial is testing a device that uses ultrasound waves to temporarily open the brain's protective barrier in patients with Alzheimer's Disease. The goal is to see if this can help medications reach the brain better. Focused ultrasound with microbubbles has been studied recently and shows promise for opening the brain's protective barrier in Alzheimer's disease treatment.
Trials for AD Patients
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
Recruiting1 award5 criteria
Westport, Connecticut
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Behavioural Intervention
Dysphagia Therapy for Alzheimer's Disease
Recruiting1 award
Madison, Wisconsin
This trial tests a saliva gel and tongue exercises to help people with Alzheimer's who have trouble swallowing. These patients are at risk of pneumonia because they can't swallow well. The saliva gel keeps their mouth moist, and the exercises make their tongue stronger to help with swallowing.
Ultrasound Therapy
ExAblate BBB Disruption for Alzheimer's Disease
Recruiting1 award5 criteria
New York, New York
This trial is testing a device that uses ultrasound waves to temporarily open the brain's protective barrier in patients with Alzheimer's Disease. The goal is to see if this can help medications reach the brain better. Focused ultrasound with microbubbles has been studied recently and shows promise for opening the brain's protective barrier in Alzheimer's disease treatment.
Phase 3 Trials
MRI + PET Scans for Cognitive Impairment
Recruiting2 awardsPhase 3
Irvine, California
This trial is studying how well MRI, PET, and cognitive testing work in detecting changes in the brain that may happen before someone shows symptoms of cognitive decline. They will also look at tau protein in the brain with a PET scan and an investigational drug.
Monoclonal Antibodies
Donanemab for Early Alzheimer's Disease
Recruiting1 awardPhase 3
Hoover, Alabama
This trial is testing donanemab, a drug for early Alzheimer's disease. It targets people with early symptoms and specific brain changes. The drug helps remove harmful proteins from the brain, potentially slowing down or improving symptoms.
Monoclonal Antibodies
Donanemab for Alzheimer's Disease
Recruiting1 awardPhase 3
Covina, California
This trial is testing donanemab, a medication aimed at helping people with Alzheimer's Disease by removing harmful protein clumps from their brains. Donanemab has shown promise in reducing these harmful proteins in Alzheimer's disease.
Trials With No Placebo
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
Recruiting1 award5 criteria
Westport, Connecticut
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Behavioural Intervention
Dysphagia Therapy for Alzheimer's Disease
Recruiting1 award
Madison, Wisconsin
This trial tests a saliva gel and tongue exercises to help people with Alzheimer's who have trouble swallowing. These patients are at risk of pneumonia because they can't swallow well. The saliva gel keeps their mouth moist, and the exercises make their tongue stronger to help with swallowing.
Ultrasound Therapy
ExAblate BBB Disruption for Alzheimer's Disease
Recruiting1 award5 criteria
New York, New York
This trial is testing a device that uses ultrasound waves to temporarily open the brain's protective barrier in patients with Alzheimer's Disease. The goal is to see if this can help medications reach the brain better. Focused ultrasound with microbubbles has been studied recently and shows promise for opening the brain's protective barrier in Alzheimer's disease treatment.
PET/MRI Brain Imaging for Alzheimer's Disease
Recruiting1 awardPhase 2
Birmingham, Alabama
This trial uses a special imaging dye to detect harmful protein build-up in the brains of participants from the UAB Alzheimer's Disease Center. The study aims to understand how these brain changes relate to race, vascular risk factors, and cognitive health. The dye helps make these harmful proteins visible in brain scans.
Trials Offering Remuneration
Tau PET Imaging for Alzheimer's Disease
Recruiting1 awardPhase 1
Birmingham, Alabama
This trial is measuring the concentration of pathologic tau deposition in the brain using the PET tracer AV-1451 in participants in the UAB-ADC cohort in order to correlate it with demographic, clinical, genetic, and biospecimen data. The primary outcome of this imaging study is to assess interactions between race and vascular risk factors, brain tau levels measured with AV-1451-PET, and cognitive status.
[18F]3F4AP Imaging for Brain Conditions
Recruiting1 awardPhase 1
Boston, Massachusetts
This trial is testing the safety of a new imaging agent, [18F]3F4AP, in people with brain injuries, Alzheimer's Disease, and other forms of cognitive impairment. The goal is to see if this agent can help doctors better understand and treat these conditions.
EAAT2 PET Tracer for Dementia
Recruiting1 awardPhase 1 & 2
San Francisco, California
This trial tests a new imaging agent that can be seen with a PET scan to detect early brain changes in patients with Alzheimer's disease and frontotemporal dementia. The agent targets a specific brain protein that is less active in these diseases. By identifying these changes early, doctors hope to improve diagnosis and treatment.
Radiopharmaceutical
Tau Tracer Comparison for Alzheimer's Disease
Recruiting1 awardPhase 1
Berkeley, California
This trial uses special imaging agents to help visualize harmful brain proteins in people at risk of Alzheimer's disease. The agents make these proteins glow during scans, allowing doctors to see them clearly and monitor the disease.
Radiopharmaceutical
64Cu-FBP8 PET Scan for Alzheimer's Disease
Recruiting1 awardPhase 1 & 2
Boston, Massachusetts
This trial uses a special brain scan to detect certain protein levels in people ranging from normal cognitive function to those with Alzheimer's disease and related dementias. The scan helps researchers understand how these proteins are distributed in the brain.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.