Thrombopoietin Receptor Agonist
Eltrombopag for Aplastic Anemia
Recruiting1 awardPhase 2
Bethesda, Maryland
This trial is evaluating the safety and effectiveness of eltrombopag, a drug given by mouth, in people with moderate aplastic anemia or bone marrow failure and unilineage cytopenia who need treatment for significantly low blood cell counts.
Hematopoietic Stem Cell Transplantation
Haploidentical Transplant for Severe Aplastic Anemia
Recruiting3 awardsPhase 2
Memphis, Tennessee
This trial is for patients with Severe Aplastic Anemia who will receive a haploidentical transplantation (from a family member that is not fully matched). The primary objective is to assess the rate of engraftment at 30 days and overall survival (OS) and event free survival (EFS) at 1 year.
Thrombopoietin Receptor Agonist
Cyclosporine + Eltrombopag for Aplastic Anemia
Recruiting1 awardPhase 2
Bethesda, Maryland
This trial is testing whether a lower dose of cyclosporine with eltrombopag is safe and effective in people with severe aplastic anemia who have not been treated with immunosuppressive therapy and eltrombopag.
Popular Filters
Trials for MDS Patients
CAR T-cell Therapy
Gene Modified T-cells for Blood Disorders
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial will look at whether T cells from a family member can help a patient's immune system recover after a stem cell transplant, with the added safety measure of a self-destruct switch.
Alkylating agents
Stem Cell Transplant for Severe Aplastic Anemia
Recruiting1 awardPhase 2
Bethesda, Maryland
This trial is for people with severe aplastic anemia, myelodysplastic syndrome, or paroxysmal nocturnal hemoglobinuria who want to receive a stem cell transplant using peripheral blood stem cells from a family member.
Stem Cell Transplantation
Umbilical Cord Blood Transplant for Aplastic Anemia and Myelodysplastic Syndrome
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial is testing if treating people with SAA or MDS with a co-infusion of blood stem cells from a family member and cord blood stem cells from an unrelated donor is safe and effective.
Antimetabolites
Cord Blood Transplant for Blood Diseases
Recruiting1 awardPhase 1
Rochester, New York
This trial uses stem cells from a baby's umbilical cord to treat patients who need new healthy stem cells. Patients first get strong medicine to clear out unhealthy cells, then receive the new stem cells, and take medications to prevent complications. Umbilical cord blood has been used in the treatment of various diseases, including leukemias, lymphomas, and immune system disorders.
Trials for Myelodysplastic Syndrome Patients
CAR T-cell Therapy
Gene Modified T-cells for Blood Disorders
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial will look at whether T cells from a family member can help a patient's immune system recover after a stem cell transplant, with the added safety measure of a self-destruct switch.
Stem Cell Transplantation
Umbilical Cord Blood Transplant for Aplastic Anemia and Myelodysplastic Syndrome
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial is testing if treating people with SAA or MDS with a co-infusion of blood stem cells from a family member and cord blood stem cells from an unrelated donor is safe and effective.
Antimetabolites
Cord Blood Transplant for Blood Diseases
Recruiting1 awardPhase 1
Rochester, New York
This trial uses stem cells from a baby's umbilical cord to treat patients who need new healthy stem cells. Patients first get strong medicine to clear out unhealthy cells, then receive the new stem cells, and take medications to prevent complications. Umbilical cord blood has been used in the treatment of various diseases, including leukemias, lymphomas, and immune system disorders.
Trials for HLA Positive Patients
CAR T-cell Therapy
Gene Modified T-cells for Blood Disorders
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial will look at whether T cells from a family member can help a patient's immune system recover after a stem cell transplant, with the added safety measure of a self-destruct switch.
Anti-metabolites
Haploidentical Bone Marrow Transplant for Aplastic Anemia
Recruiting1 awardPhase 2
Atlanta, Georgia
This trial is testing a new treatment for severe aplastic anemia, which is a rare and serious form of bone marrow failure. The new treatment is using a haploidentical donor for transplantation, which has good response rates and significantly lower rates of acute and chronic GVHD.
Stem Cell Therapy
CD34+ Stem Cell Selection for Bone Marrow Failure Syndromes
Recruiting1 awardPhase 1 & 2
New York, New York
This trial uses a special machine to filter out harmful cells from donor blood to make stem cell transplants safer for young patients with non-cancerous diseases. By removing specific cells, it aims to prevent a serious immune reaction.
Trials With No Placebo
CAR T-cell Therapy
Gene Modified T-cells for Blood Disorders
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial will look at whether T cells from a family member can help a patient's immune system recover after a stem cell transplant, with the added safety measure of a self-destruct switch.
Anti-metabolites
Haploidentical Bone Marrow Transplant for Aplastic Anemia
Recruiting1 awardPhase 2
Atlanta, Georgia
This trial is testing a new treatment for severe aplastic anemia, which is a rare and serious form of bone marrow failure. The new treatment is using a haploidentical donor for transplantation, which has good response rates and significantly lower rates of acute and chronic GVHD.
Antimetabolites
Bone Marrow Transplant for Dyskeratosis Congenita
Recruiting3 awardsPhase 2
Los Angeles, California
This trial tests a new bone marrow transplant method for patients with Dyskeratosis congenita. It uses fludarabine and antibodies to avoid harmful side effects, aiming to improve survival and reduce complications. Fludarabine-based regimens have been shown to be effective and feasible in reducing transplant-related morbidity in patients with Dyskeratosis congenita.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.