Corticosteroid
Pregnenolone for Autism
Recruiting0 awardsPhase 2
Stanford, California
This trial is testing pregnenolone, a natural hormone in the brain, to see if it can help people with autism. Pregnenolone is part of a neurosteroid pathway that has been studied for its potential therapeutic value in stress and drug abuse-related disorders. The goal is to find out if it can reduce irritability and sensitivity to sensory differences, and improve social communication. Researchers hope this will lead to better treatments for autism.
Selective Serotonin Reuptake Inhibitor
Escitalopram for Autism
Recruiting0 awardsPhase 2
Kansas City, Kansas
This trial aims to study how a medication called escitalopram affects the brain in adolescents with autism. The researchers want to see if escitalopram can help with rigid and repetitive behaviors in adolescents
Behavioural Intervention
Parent-Mediated Intervention for Autism Spectrum Disorder
Recruiting1 award
Halifax, Nova Scotia
This trial tests two therapies for young children with autism who haven't responded well to usual treatments. The therapies involve parents playing with their children to encourage communication and social skills. One therapy focuses on general improvement, while the other targets specific weaknesses.
Behavioural Intervention
Training Programs for Autism
Recruiting1 award
Sacramento, California
This trial is testing whether a training program called TEAMS, which uses Motivational Interviewing strategies, can help providers implement evidence-based interventions for children with autism spectrum disorder more effectively.
Dopamine Precursor
L-DOPA + Social Skills Training for Autism Spectrum Disorder
Recruiting0 awardsPhase 2
Los Angeles, California
This trial will use L-DOPA or placebo to study social reward processes in adolescents and young adults with ASD, and how dopamine affects these processes. It will enroll 56 participants with ASD and 18 healthy controls.
Popular Filters
Trials for Asperger Syndrome Patients
Cognitive Behavioral Therapy
Facing Your Fears Therapy for ASD with Intellectual Disability
Recruiting1 award4 criteria
Aurora, Colorado
This trial tests a program called 'Facing Your Fears' for teenagers with autism and intellectual disabilities. It aims to help them manage anxiety by teaching coping skills. The 'Facing Your Fears' program has been previously adapted and tested for adolescents with high-functioning autism spectrum disorders and anxiety, showing encouraging initial results.
Cannabinoid
CBD for Autism
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial is testing if cannabidiol (CBD) can help with anxiety, mood issues, sleep problems, and agitation in adults with autism spectrum disorder (ASD). Participants will take CBD pills for a period of time. The study aims to see if CBD is effective and safe for these psychiatric problems. Cannabidiol (CBD) has shown promise in treating psychotic symptoms and anxiety, but there is not enough high-quality evidence for its clinical use in psychiatric disorders.
Atypical Antipsychotic
Risperidone vs Aripiprazole for Weight Gain in Children with Autism
Recruiting3 awardsPhase 4
Nashville, Tennessee
This trial is comparing two medicines, aripiprazole and risperidone, to see which one causes more weight gain in children with autism. The study focuses on children under 18 who have behavior problems like irritability and aggression. These medicines help by calming brain activity to improve behavior. The main goal is to find out which medicine leads to less weight gain over a few months. Aripiprazole and risperidone are both FDA-approved for treating irritability in children with autism.
Behavioural Intervention
N-Acetylcysteine for Autism
Recruiting1 awardPhase 2
Stanford, California
This trial aims to see if NAC, a safe nutritional supplement, can help reduce repetitive behaviors in children with autism by balancing brain chemicals. N-Acetylcysteine (NAC) has been studied for its potential benefits in treating obsessive-compulsive spectrum disorders and irritability in autism spectrum disorders.
Phase 3 Trials
Atypical Antipsychotic
Cariprazine for Pediatric Schizophrenia
Recruiting2 awardsPhase 3
Dothan, Alabama
This trial is testing the safety and effectiveness of cariprazine in children and teens with schizophrenia, bipolar I disorder, or autism. The goal is to see if the medication is safe and beneficial for use in these young patients.
Serotonin Receptor Antagonist
Pimavanserin for Autism Spectrum Disorder
Recruiting1 awardPhase 2 & 3
Las Vegas, Nevada
This trial is testing pimavanserin, a medication that may help reduce irritability in children and teenagers with autism. The study focuses on kids aged 5 to 17 who have this symptom. Pimavanserin works by balancing brain chemicals to help them feel calmer. The goal is to see if the medication is safe and effective over time.
Melatonin Receptor Agonist
Tasimelteon for Autism and Sleep Disorders
Recruiting3 awardsPhase 3
San Jose, California
This trial is testing a daily pill called tasimelteon to help children and adults with Autism Spectrum Disorder (ASD) who have trouble sleeping. The medication aims to improve sleep by helping to regulate the body's internal clock.
Behavioral Intervention
Telehealth vs In-Person Behavior Therapy for Autism
Recruiting0 awardsPhase 2 & 3
Stanford, California
This trial is aiming to find out if behavior therapy, which helps children with autism spectrum disorder (ASD) manage difficult behaviors, can be just as effective when done through telehealth (online) as
Behavioural Intervention
Lumateperone for Autism
Recruiting1 awardPhase 3
Little Rock, Arkansas
This trial is testing a new medication for irritability in children with Autism Spectrum Disorder. It will involve multiple medical centers and the participants will be randomly assigned to receive either the new medication or a placebo.
Trials With No Placebo
Cognitive Behavioral Therapy
Facing Your Fears Therapy for ASD with Intellectual Disability
Recruiting1 award4 criteria
Aurora, Colorado
This trial tests a program called 'Facing Your Fears' for teenagers with autism and intellectual disabilities. It aims to help them manage anxiety by teaching coping skills. The 'Facing Your Fears' program has been previously adapted and tested for adolescents with high-functioning autism spectrum disorders and anxiety, showing encouraging initial results.
Atypical Antipsychotic
Risperidone vs Aripiprazole for Weight Gain in Children with Autism
Recruiting3 awardsPhase 4
Nashville, Tennessee
This trial is comparing two medicines, aripiprazole and risperidone, to see which one causes more weight gain in children with autism. The study focuses on children under 18 who have behavior problems like irritability and aggression. These medicines help by calming brain activity to improve behavior. The main goal is to find out which medicine leads to less weight gain over a few months. Aripiprazole and risperidone are both FDA-approved for treating irritability in children with autism.
Behavioural Intervention
N-Acetylcysteine for Autism
Recruiting1 awardPhase 2
Stanford, California
This trial aims to see if NAC, a safe nutritional supplement, can help reduce repetitive behaviors in children with autism by balancing brain chemicals. N-Acetylcysteine (NAC) has been studied for its potential benefits in treating obsessive-compulsive spectrum disorders and irritability in autism spectrum disorders.
Behavioural Intervention
AI Modules for Improving Social Communication in Autism
Recruiting1 award2 criteria
Stanford, California
This trial aims to see if AI can effectively deliver interventions for individuals with autism spectrum disorder who struggle with socialization. The study will use an app on a phone or computer to provide practice and feedback on
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.