Anti-metabolites
MTX101 for Migraine
Recruiting0 awardsPhase 2
La Jolla, California
This trial aims to determine if the drug MTX101 is effective in treating acute migraine attacks in adults and to assess its safety. Participants will take either MTX101 or a placebo for one migraine attack with each treatment. They will visit the clinic twice and have one phone call over a 4-week period for checkups and tests. Researchers will compare the effectiveness of MTX101 to a placebo in reducing headache pain and the need for rescue medication, as well as monitor any side effects experienced by participants.
Behavioural Intervention
Mild Intermittent Hypoxia for Spinal Cord Injury
Recruiting0 awards4 criteria
Detroit, Michigan
This trial is testing whether low oxygen exposure can help people with spinal cord injuries who have trouble controlling their blood pressure and breathing during sleep. The goal is to see if this treatment can improve their health and make daily activities easier for them.
Autoimmune Investigation for POTS
Recruiting3 awards5 criteria
Oklahoma City, Oklahoma
This trial is studying whether certain immune proteins are causing or worsening symptoms in people with POTS, a condition that makes it hard for them to stand without feeling dizzy or faint. The researchers will study people with POTS to see if these proteins are more common in those with the condition and if these levels vary.
Behavioural Intervention
Backward vs Forward Walking Training for Multiple Sclerosis
Recruiting1 award3 criteria
Detroit, Michigan
This trial will test if practicing walking backward can help people with multiple sclerosis (MS) improve their balance and reduce their risk of falling. People with MS often have trouble with mobility and thinking, leading to frequent falls. Current methods like forward walking exercises haven't been very effective. The study will compare backward walking to forward walking to see which is better for improving motor function and preventing falls.
Neurostimulation Device
VNS for Epilepsy
Recruiting1 award2 criteria
Louisville, Kentucky
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
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Trials for Neuro-Oncology Patients
Hormone Therapy
Locomotor Training + Testosterone for Spinal Cord Injury
Recruiting2 awardsPhase 2
Gainesville, Florida
This trial will study the feasibility of using testosterone replacement therapy along with locomotor training to improve walking function in men with spinal cord injuries and low testosterone levels.
Alpha-2 Adrenergic Agonist
Dexmedetomidine for Postoperative Cognitive Dysfunction
Recruiting3 awardsPhase 4
Toronto, Ontario
This trial is testing whether the drug Dexmedetomidine can prevent postoperative cognitive dysfunction (POCD), which is when patients have trouble thinking and remembering after surgery.
Behavioral Intervention
Tai Chi for Insomnia in Breast Cancer Survivors
Recruiting1 award6 criteria
Los Angeles, California
This trial will examine the efficacy of TTC on sleep impairments in women with breast cancer. #BreastCancer is common in women; TTC may improve sleep, fatigue & inflammation, & help long-term survival.
Trials for Nervous System Disorders Patients
Hormone Therapy
Locomotor Training + Testosterone for Spinal Cord Injury
Recruiting2 awardsPhase 2
Gainesville, Florida
This trial will study the feasibility of using testosterone replacement therapy along with locomotor training to improve walking function in men with spinal cord injuries and low testosterone levels.
Alpha-2 Adrenergic Agonist
Dexmedetomidine for Postoperative Cognitive Dysfunction
Recruiting3 awardsPhase 4
Toronto, Ontario
This trial is testing whether the drug Dexmedetomidine can prevent postoperative cognitive dysfunction (POCD), which is when patients have trouble thinking and remembering after surgery.
Behavioral Intervention
Tai Chi for Insomnia in Breast Cancer Survivors
Recruiting1 award6 criteria
Los Angeles, California
This trial will examine the efficacy of TTC on sleep impairments in women with breast cancer. #BreastCancer is common in women; TTC may improve sleep, fatigue & inflammation, & help long-term survival.
Trials With No Placebo
Behavioural Intervention
Neurostimulation for Autonomic Dysfunction
Recruiting1 award1 criteria
Milwaukee, Wisconsin
This trial is focusing on children with gut-brain disorders, which can cause symptoms like nausea, vomiting, and anxiety. Current treatments for these disorders often focus on treating the symptoms rather than the underlying cause
Behavioural Intervention
Alternating-Frequency DBS for Parkinson's Disease
Recruiting1 awardPhase 1
Cleveland, Ohio
This trial is testing a new type of brain stimulation that changes how often electrical signals are sent to the brain. It aims to help Parkinson's Disease patients who have trouble with balance and walking, problems that current treatments can't fix. By adjusting the stimulation pattern, researchers hope to improve these movement issues.
Hormone Therapy
Locomotor Training + Testosterone for Spinal Cord Injury
Recruiting2 awardsPhase 2
Gainesville, Florida
This trial will study the feasibility of using testosterone replacement therapy along with locomotor training to improve walking function in men with spinal cord injuries and low testosterone levels.
Alpha-2 Adrenergic Agonist
Dexmedetomidine for Postoperative Cognitive Dysfunction
Recruiting3 awardsPhase 4
Toronto, Ontario
This trial is testing whether the drug Dexmedetomidine can prevent postoperative cognitive dysfunction (POCD), which is when patients have trouble thinking and remembering after surgery.
Neurostimulation Device
Epidural Spinal Cord Stimulation for Spinal Cord Injury
Recruiting1 award9 criteria
Minneapolis, Minnesota
This trial will test a way to improve epidural spinal cord stimulation for people with spinal cord injuries. The study will also look at how well autonomic function (such as blood pressure control) and other functions improve.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.