Cystic Fibrosis Clinical Trials 2024

Cystic Fibrosis research studies recruiting patients in 2024 need your help. Receive premium care & cutting edge treatments by enrolling in cystic fibrosis clinical trials today.

Popular Trials

Xenon-129 MRI for Pulmonary Disease

Recruiting1 awardPhase 2

Toronto, Ontario

This trial is looking at whether a new MRI technique called Xenon-129 MRI can help show differences in the lungs of people with cystic fibrosis or asthma, compared to healthy people.

Antioxidant Therapy for Cystic Fibrosis

Recruiting0 awards10 criteria

Augusta, Georgia

This trial will explore if oxidative stress contributes to both artery dysfunction and exercise intolerance in CF patients.

Clinical Tool for Cystic Fibrosis Waitlist Mortality

Recruiting1 award3 criteria

Cleveland, Ohio

This trial aimed to improve waitlist mortality in patients with cystic fibrosis by implementing a clinical tool.

Behavioural Intervention

Exercise Program for Cystic Fibrosis

Recruiting1 award1 criteria

Birmingham, Alabama

This trial will help researchers learn if an exercise program is safe and helpful for patients with a CF exacerbation.

Biguanide

Metformin for Cystic Fibrosis

Recruiting1 awardPhase 2

Kansas City, Kansas

This trial will test if metformin can help improve airway function in those with CF-related diabetes.

Hormone Therapy

Estrogen Supplementation for Cystic Fibrosis

Recruiting3 awardsPhase 4

Baltimore, Maryland

This trial studies how estrogen skin patches affect bone health in young women with cystic fibrosis. Participants will use the patches regularly and undergo various health assessments. The goal is to see if this treatment can improve their bone health and quality of life. Estrogen replacement is recommended for female patients with CF-related bone disease to restore bone mineral density.

Popular Filters

Trials for CF Patients

Behavioural Intervention

Behavioral Counseling + Exercise for Cystic Fibrosis

Recruiting1 award5 criteria

Birmingham, Alabama

This trial will test if starting an exercise program while in the hospital helps patients with cystic fibrosis.

Monoclonal Antibodies

Denosumab for Osteoporosis in Cystic Fibrosis

Recruiting3 awardsPhase 4

Dallas, Texas

This trial is testing a new way to treat CF patients with bone disease. Up to 100 subjects with CF will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. If results indicate bone disease, subjects will receive treatment with Denosumab for up to 5 years.

Cephalosporin Antibiotic

Ceftaroline for Cystic Fibrosis

Recruiting3 awardsPhase 4

Cincinnati, Ohio

This trial is testing a new way to give the antibiotic ceftaroline to kids with cystic fibrosis who also have a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA).

Procedure

Glycine Buffer for Airway pH Measurement in Asthma

Recruiting1 awardPhase 1 & 2

Indianapolis, Indiana

This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.

CFTR Modulator

Symdeko for Cystic Fibrosis

Recruiting3 awardsPhase < 1

Birmingham, Alabama

This trial will test whether unapproved drugs can improve the function of CFTR mutations in people with CF.

Antibiotic

Streamlined MRSA Treatment for Cystic Fibrosis

Recruiting3 awardsPhase 2

Denver, Colorado

This trial is testing a new, streamlined treatment for MRSA in patients with cystic fibrosis. The goal is to see if it is effective and safe.

Trials for Cystic Fibrosis Liver Disease Patients

Behavioural Intervention

Behavioral Counseling + Exercise for Cystic Fibrosis

Recruiting1 award5 criteria

Birmingham, Alabama

This trial will test if starting an exercise program while in the hospital helps patients with cystic fibrosis.

Monoclonal Antibodies

Denosumab for Osteoporosis in Cystic Fibrosis

Recruiting3 awardsPhase 4

Dallas, Texas

This trial is testing a new way to treat CF patients with bone disease. Up to 100 subjects with CF will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. If results indicate bone disease, subjects will receive treatment with Denosumab for up to 5 years.

Cephalosporin Antibiotic

Ceftaroline for Cystic Fibrosis

Recruiting3 awardsPhase 4

Cincinnati, Ohio

This trial is testing a new way to give the antibiotic ceftaroline to kids with cystic fibrosis who also have a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA).

Procedure

Glycine Buffer for Airway pH Measurement in Asthma

Recruiting1 awardPhase 1 & 2

Indianapolis, Indiana

This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.

CFTR Modulator

Symdeko for Cystic Fibrosis

Recruiting3 awardsPhase < 1

Birmingham, Alabama

This trial will test whether unapproved drugs can improve the function of CFTR mutations in people with CF.

Antibiotic

Streamlined MRSA Treatment for Cystic Fibrosis

Recruiting3 awardsPhase 2

Denver, Colorado

This trial is testing a new, streamlined treatment for MRSA in patients with cystic fibrosis. The goal is to see if it is effective and safe.

Trials for CFTR Positive Patients

Procedure

Glycine Buffer for Airway pH Measurement in Asthma

Recruiting1 awardPhase 1 & 2

Indianapolis, Indiana

This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.

CFTR Modulator

Symdeko for Cystic Fibrosis

Recruiting3 awardsPhase < 1

Birmingham, Alabama

This trial will test whether unapproved drugs can improve the function of CFTR mutations in people with CF.

Angiotensin II Receptor Blocker

Losartan for Cystic Fibrosis

Recruiting1 awardPhase < 1

Kansas City, Kansas

This trial is testing losartan, a blood pressure medication, to see if it can help clear mucus from the lungs of cystic fibrosis patients who can't use current treatments. These patients need alternative treatments because they don't respond to existing options. Losartan may reduce lung inflammation, making it easier for them to breathe.

Hormone Therapy

Incretin Hormones for Cystic Fibrosis

Recruiting1 award5 criteria

Philadelphia, Pennsylvania

This trial is looking at the role of incretin hormones in Cystic Fibrosis patients with normal glucose levels to see if it has an effect on CFTR function.

GLP-1 Agonist

GLP-1 Agonist Therapy for Cystic Fibrosis-related Diabetes

Recruiting1 awardPhase 2

Philadelphia, Pennsylvania

This trial looks at whether a weekly injection of a medication called dulaglutide can help improve early-phase insulin secretion and glucose tolerance in people with cystic fibrosis-related diabetes.

CFTR Modifiers

CFTR Modulators for Cystic Fibrosis

Recruiting1 award16 criteria

Cincinnati, Ohio

This trial will test if current CF treatments can be effective for new, non-approved CF gene mutations.

Phase 3 Trials

CFTR Modulator

ELX/TEZ/IVA for Cystic Fibrosis

Recruiting4 awardsPhase 3

Edmonton

This trial investigates the safety, effectiveness and effects of a drug to treat cystic fibrosis in people with a certain gene mutation.

CFTR Modulator

ELX/TEZ/IVA for Cystic Fibrosis

Recruiting2 awardsPhase 3

Tucson, Arizona

This trial is testing a combination of three medications to help people with cystic fibrosis. The medications work together to fix a broken protein in the body, which can improve lung function and overall health.

Antibiotics for Cystic Fibrosis

Recruiting1 awardPhase 3

Vancouver, British Columbia

This trial tests if the antibiotic Cephalexin can help children with cystic fibrosis and a specific bacterial infection (MSSA) by improving their lung function. Cephalexin has been used in previous studies for antistaphylococcal prophylaxis in infants and young children with cystic fibrosis.

CFTR Modulator

VX-121 Combination Therapy for Cystic Fibrosis

Recruiting2 awardsPhase 3

Orlando, Florida

This trialstudies the safety and effectiveness of a drug for people with cystic fibrosis over the long-term.

CFTR Modulator

VX-121 + Tezacaftor + Deutivacaftor for Cystic Fibrosis

Recruiting2 awardsPhase 3

Aurora, Colorado

This trial tests a combination of three drugs for cystic fibrosis patients with a specific genetic mutation. The drugs work together to fix the faulty protein in their cells, helping their lungs and other organs function better. Trikafta is a combination of three drugs (elexacaftor, tezacaftor, and ivacaftor) that target the F508del mutation in the CFTR gene.

Antibiotic

Rifaximin for Bloating in Cystic Fibrosis

Recruiting0 awardsPhase 2 & 3

Winston-Salem, North Carolina

This trial is testing rifaximin, an antibiotic, to help people with cystic fibrosis who have gut symptoms like bloating. The antibiotic works by balancing gut bacteria to reduce discomfort. Rifaximin has been used to treat travelers' diarrhea and other conditions, and it has shown effectiveness in reducing symptoms of irritable bowel syndrome (IBS).

Trials With No Placebo

Behavioural Intervention

Behavioral Counseling + Exercise for Cystic Fibrosis

Recruiting1 award5 criteria

Birmingham, Alabama

This trial will test if starting an exercise program while in the hospital helps patients with cystic fibrosis.

Monoclonal Antibodies

Denosumab for Osteoporosis in Cystic Fibrosis

Recruiting3 awardsPhase 4

Dallas, Texas

This trial is testing a new way to treat CF patients with bone disease. Up to 100 subjects with CF will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. If results indicate bone disease, subjects will receive treatment with Denosumab for up to 5 years.

Cephalosporin Antibiotic

Ceftaroline for Cystic Fibrosis

Recruiting3 awardsPhase 4

Cincinnati, Ohio

This trial is testing a new way to give the antibiotic ceftaroline to kids with cystic fibrosis who also have a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA).

Procedure

Glycine Buffer for Airway pH Measurement in Asthma

Recruiting1 awardPhase 1 & 2

Indianapolis, Indiana

This trial is testing a new way to measure airway pH in people with asthma and cystic fibrosis, using a new inhaled drug. The airway pH will help doctors tailor treatment plans for these conditions.

CFTR Modulator

Symdeko for Cystic Fibrosis

Recruiting3 awardsPhase < 1

Birmingham, Alabama

This trial will test whether unapproved drugs can improve the function of CFTR mutations in people with CF.

Antibiotic

Streamlined MRSA Treatment for Cystic Fibrosis

Recruiting3 awardsPhase 2

Denver, Colorado

This trial is testing a new, streamlined treatment for MRSA in patients with cystic fibrosis. The goal is to see if it is effective and safe.

View More Related Trials

Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.