Procedure
Kidney + Stem Cell Transplant for Immune Tolerance
Recruiting1 awardPhase 1 & 2
Stanford, California
This trial is testing whether blood stem cells, when injected after kidney transplantation and combined with lymphoid irradiation, will change the immune system such that immunosuppressive drugs can be completely withdrawn.
Taxane
Chemotherapy + Stem Cell Transplant for Breast Cancer
Recruiting1 awardPhase 2
Duarte, California
This trial is testing a combination of strong cancer drugs, stem cell replacement, surgery, and radiation in patients with severe stage IIIB breast cancer. The goal is to kill cancer cells, help the body recover, remove the tumor, and eliminate any remaining cancer cells.
Topoisomerase II inhibitors
IMRT + Chemotherapy + Stem Cell Transplant for Leukemia
Recruiting1 awardPhase 1 & 2
Duarte, California
This trial is giving IMRT with chemotherapy to patients with relapsed or refractory ALL or AML before a donor stem cell transplant. The aim is to find out the side effects of this treatment and the best dose of IMRT to give, as well as how well the IMRT and chemotherapy work in treating patients.
Popular Filters
Trials for Mantle Cell Lymphoma Patients
Stem Cell Transplantation
Stem Cell Transplant for Non-Hodgkin's Lymphoma
Recruiting1 awardPhase 2
Saint Louis, Missouri
This trial is testing a new two-step approach to treating high-risk non-Hodgkin's lymphoma. First, the patient's own blood cells are transplanted. Then, a transplant from another individual is performed. The goal is to improve the chances for long-term control of lymphoma.
Trials for Multiple Myeloma Patients
Antimetabolite
Chemotherapy + Stem Cell Transplant for Multiple Myeloma
Recruiting1 awardPhase 1
Duarte, California
This trial is studying the side effects and best dose of bortezomib when given together with fludarabine phosphate and melphalan with or without total marrow irradiation for patients with high-risk stage I or II multiple myeloma.
Monoclonal Antibodies
PD-1 Blockade + Dendritic Cell Fusion Vaccine + CT-011 for Multiple Myeloma
Recruiting1 awardPhase 2
Boston, Massachusetts
This trial is testing the safety of CT-011 and the combination of the Dendritic cell fusion vaccine and CT-011 after ASCT in patients with multiple myeloma. They are also testing to see if the combination is more successful in preventing or delaying the disease from coming back, compared to treatment with ASCT alone.
Trials for HLA Positive Patients
Topoisomerase II inhibitors
Stem Cell Transplant for Autoimmune Neurological Diseases
Recruiting1 awardPhase 2
Denver, Colorado
This trial tests a combination of strong chemotherapy and an immune-suppressing medicine followed by a stem cell transplant. It targets patients with autoimmune neurological diseases that haven't improved with other treatments. The treatment aims to weaken the immune system to stop it from attacking the nervous system and then helps the body recover by making new blood cells. High-dose chemotherapy followed by a stem cell transplant has been shown to improve various autoimmune diseases.
Stem Cell Therapy
CD34+ Stem Cell Selection for Bone Marrow Failure Syndromes
Recruiting1 awardPhase 1 & 2
New York, New York
This trial uses a special machine to filter out harmful cells from donor blood to make stem cell transplants safer for young patients with non-cancerous diseases. By removing specific cells, it aims to prevent a serious immune reaction.
Probiotic
Probiotics for Preventing Graft-versus-Host Disease
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing whether Lactobacillus plantarum, a beneficial bacteria found in foods like yogurt, can prevent a serious gut complication called acute graft versus host disease in young patients receiving stem cell transplants. The bacteria may help by keeping the gut healthy and reducing inflammation. Lactobacillus plantarum has been used in human studies to promote beneficial effects in the immune system, alleviate intestinal disorders, and reduce the risk of cardiovascular disease. The study will compare patients taking Lactobacillus plantarum to those not taking it.
CAR T-cell Therapy
Gene Modified T-cells for Blood Disorders
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial will look at whether T cells from a family member can help a patient's immune system recover after a stem cell transplant, with the added safety measure of a self-destruct switch.
Trials for RB1 Positive Patients
Stem Cell Therapy
CD34+ Stem Cell Selection for Bone Marrow Failure Syndromes
Recruiting1 awardPhase 1 & 2
New York, New York
This trial uses a special machine to filter out harmful cells from donor blood to make stem cell transplants safer for young patients with non-cancerous diseases. By removing specific cells, it aims to prevent a serious immune reaction.
Probiotic
Probiotics for Preventing Graft-versus-Host Disease
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing whether Lactobacillus plantarum, a beneficial bacteria found in foods like yogurt, can prevent a serious gut complication called acute graft versus host disease in young patients receiving stem cell transplants. The bacteria may help by keeping the gut healthy and reducing inflammation. Lactobacillus plantarum has been used in human studies to promote beneficial effects in the immune system, alleviate intestinal disorders, and reduce the risk of cardiovascular disease. The study will compare patients taking Lactobacillus plantarum to those not taking it.
CAR T-cell Therapy
Gene Modified T-cells for Blood Disorders
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial will look at whether T cells from a family member can help a patient's immune system recover after a stem cell transplant, with the added safety measure of a self-destruct switch.
Anti-metabolites
Marrow Irradiation + Chemotherapy for Leukemia
Recruiting1 awardPhase 1
Duarte, California
This trial is testing the side effects and best dose of total marrow and lymphoid irradiation when given with fludarabine and melphalan before a donor stem cell transplant in people with high-risk acute leukemia or myelodysplastic syndrome.
Phase 3 Trials
Topoisomerase II inhibitors
Chemotherapy + Stem Cell Transplant for Brain Cancer
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial is studying two different chemotherapy combinations to compare how well they work in treating young patients with newly diagnosed supratentorial primitive neuroectodermal tumors or high-risk medulloblastoma.
Chemotherapy
Stem Cell Transplant for Acute Lymphoblastic Leukemia
Recruiting3 awardsPhase 2 & 3
Calgary
This trial is for children and adolescents with ALL who are in complete morphological remission and need a myeloablative conditioning regimen for HSCT. The patients are stratified according to the transplantation modalities available to them.
Cell Therapy
Stem Cell Transplant for Blood Cancer
Recruiting1 awardPhase 2 & 3
Milwaukee, Wisconsin
This trial is testing a new stem cell transplant method for people with blood cancer who don't have a perfect match for a donor. They will be observed for one year to see how well they engraft and don't get leukemia again.
Bruton's Tyrosine Kinase (BTK) Inhibitor
Ibrutinib + Stem Cell Transplant for Lymphoma
Recruiting1 awardPhase 3
Anchorage, Alaska
This trial is studying whether adding ibrutinib to chemotherapy before and after stem cell transplant helps the transplant work better in patients with relapsed or refractory diffuse large B-cell lymphoma.
Trials With No Placebo
Gene Therapy
Gene Therapy for Sickle Cell Anemia
Recruiting1 awardPhase 1
Boston, Massachusetts
This trial explores a new treatment called gene therapy for genetic diseases. Gene therapy involves using the patient's own genetic material to fix or replace a diseased gene with the goal of curing the disease. The
Behavioral Intervention
Positive Psychology for Bone Marrow Transplant Survivors
Recruiting1 award
Tampa, Florida
"This trial is studying how a positive psychology program called PATH can help improve anxiety, depression, and quality of life in people who have had a stem cell transplant, compared to standard care."
Topoisomerase II inhibitors
Chemotherapy + Stem Cell Transplant for Brain Cancer
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial is studying two different chemotherapy combinations to compare how well they work in treating young patients with newly diagnosed supratentorial primitive neuroectodermal tumors or high-risk medulloblastoma.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.