Depression Clinical Trials in New York, NY

View the best 10 depression medical studies in New York, New York. Access promising new therapies by applying to a New York-based Depression clinical trial.

Trials in New York, New York

Here are the top 10 medical studies for depression in New York, New York

Transcranial Photobiomodulator

Photobiomodulation

Recruiting1 award3 criteria

This trial is testing a special kind of invisible light aimed at the forehead to help people with depression. The light might improve blood flow in the brain. About 60 people with depression will be part of this study to see if this treatment works.

Aticaprant

Recruiting1 awardPhase 3

This trial aims to see if aticaprant is effective in preventing the return of depression symptoms when added to antidepressant therapy in individuals with major depressive disorder who have already responded well to aticaprant treatment

AXS-05

Behavioural Intervention

Recruiting3 awardsPhase 4

This trial is testing AXS-05, a new medication, to see if it can prevent depression from returning in people who have already improved with it. The study focuses on those with major depressive disorder and aims to maintain their balanced brain chemicals to keep them feeling better. AXS-05 (a combination of dextromethorphan and bupropion) has shown positive results in previous trials for major depressive disorder.

PATH-Pain

Behavioral Intervention

Recruiting1 award

This trial tests PATH-Pain therapy in older adults with cognitive issues, chronic pain, and depression. The therapy aims to help them manage pain, improve mood, and enhance thinking skills through regular sessions.

Integrative-Mind-Body Skills Group

Behavioral Intervention

Recruiting1 award

This trial tests a program that teaches meditation, mindfulness, and relaxation techniques to help medical graduate students manage stress and improve their mood.

Connecting and Reflecting Experience (CARE) Program

Behavioral Intervention

Recruiting1 award4 criteria

This trial is testing a group therapy program called CARE for parents with postpartum depression or anxiety. The program helps parents understand their own and their baby's thoughts and feelings to improve mental health and reduce stress. The study targets parents with infants aged 3 to 12 months who are receiving care at Montefiore Medical Center.

Learning through feedback

Behavioral Intervention

Recruiting1 award4 criteria

This trial will study how different feedback timing affects learning and brain function in people with TBI, with and without depression.

Affective Awareness

Behavioral Intervention

Recruiting1 awardPhase 1

This trial tests a new approach to help veterans with serious mental illness who are at risk of suicide. The treatment combines group education sessions and a smartphone app to improve emotional awareness and social functioning. By helping veterans understand their emotions better, the goal is to reduce their suicide risk.

Valera Smart Phone Application

Recruiting1 award

This trial aims to see if a custom mobile app can help young people with lupus stay engaged in their medical care and manage depression. The study focuses on adolescents and young adults from the Bronx, ages 15-24. The app offers personalized support to help them keep up with health appointments and improve their mood.

Pramipexole

Dopamine Agonist

Recruiting0 awardsPhase 2

This trial tests if pramipexole can help adults with anxiety or depression feel more socially connected. Pramipexole increases dopamine levels in the brain, which may improve how people respond to positive social interactions. The study will measure brain activity, behavior, and self-reported feelings before and after a period of treatment. Pramipexole has shown potential to improve mood and reduce anxiety in both experimental and clinical settings.

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Phase 3 Trials

NMDA Receptor Antagonist

Nebulized Ketamine for Depression

Recruiting2 awardsPhase 3

Brooklyn, New York

This trial is testing nebulized ketamine to see if it can help reduce depressive symptoms in people with moderate to severe depression. It is a controlled study where neither the participants nor the researchers know who

NMDA Receptor Antagonist

Esketamine vs. Ketamine for Depression

Recruiting2 awardsPhase 3

Milford, Connecticut

This trial aims to compare the effectiveness, acceptability, and side effects of ketamine delivered through an IV and Esketamine taken as a nasal spray for treating treatment-resistant depression. Researchers will assess how