M5049 for Myositis
Recruiting0 awardsPhase 2
Rockland, Massachusetts
This trial is testing a pill called M5049 for people with muscle diseases known as dermatomyositis (DM) and polymyositis (PM). These conditions cause muscle inflammation and weakness. The pill aims to reduce inflammation and improve muscle strength over several months.
Complement Pathway Inhibitor
RAY121 for Immune System Disorders
Recruiting1 awardPhase 1
Portland, Oregon
This trial is testing a new drug called RAY121, which aims to help people with certain immune system diseases by blocking a part of the immune system that causes inflammation. The trial will check if the drug is safe and effective for patients with conditions like APS, BP, BS, DM, IMNM, and ITP.
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Trials for DM Patients
Procedure
Sodium Thiosulfate for Calcinosis
Recruiting1 awardPhase 2
Pittsburgh, Pennsylvania
This trial aims to test the safety and effectiveness of injecting STS directly into calcinosis lesions in patients with certain autoimmune diseases. The injection process will be guided by ultrasound, and the effects on lesion
CAR T-cell Therapy
CAR T Therapy for Dermatomyositis
Recruiting1 awardPhase 1
Stanford, California
This trial tests a new therapy in adults with dermatomyositis. The therapy modifies their white blood cells to target and destroy harmful B cells, aiming to reset their immune system and reduce disease symptoms. This new treatment shows promising results in similar conditions.
Monoclonal Antibodies
Efgartigimod SC for Myositis
Recruiting2 awardsPhase 3
Beverly Hills, California
This trial aims to check the safety and effectiveness of an injectable medication called efgartigimod PH20 SC in adults with muscle inflammation who participated in an earlier phase. The medication works by reducing harmful proteins that cause muscle problems.
Trials for Systemic Lupus Erythematosus Patients
Procedure
Sodium Thiosulfate for Calcinosis
Recruiting1 awardPhase 2
Pittsburgh, Pennsylvania
This trial aims to test the safety and effectiveness of injecting STS directly into calcinosis lesions in patients with certain autoimmune diseases. The injection process will be guided by ultrasound, and the effects on lesion
CAR T-cell Therapy
CAR T Therapy for Dermatomyositis
Recruiting1 awardPhase 1
Stanford, California
This trial tests a new therapy in adults with dermatomyositis. The therapy modifies their white blood cells to target and destroy harmful B cells, aiming to reset their immune system and reduce disease symptoms. This new treatment shows promising results in similar conditions.
Monoclonal Antibodies
Efgartigimod SC for Myositis
Recruiting2 awardsPhase 3
Beverly Hills, California
This trial aims to check the safety and effectiveness of an injectable medication called efgartigimod PH20 SC in adults with muscle inflammation who participated in an earlier phase. The medication works by reducing harmful proteins that cause muscle problems.
Phase 3 Trials
Monoclonal Antibodies
Efgartigimod SC for Myositis
Recruiting2 awardsPhase 3
Beverly Hills, California
This trial aims to check the safety and effectiveness of an injectable medication called efgartigimod PH20 SC in adults with muscle inflammation who participated in an earlier phase. The medication works by reducing harmful proteins that cause muscle problems.
Monoclonal Antibodies
Efgartigimod for Myositis
Recruiting0 awardsPhase 2 & 3
Beverly Hills, California
This trial is testing an injectable medication called efgartigimod PH20 SC in people with certain muscle inflammation diseases. The goal is to see if it helps improve their condition by lowering harmful proteins in their blood. The study focuses on patients with specific subtypes of these diseases who often don't respond well to usual treatments. Efgartigimod was developed for autoimmune diseases and has been approved for treating a specific muscle condition in adults.
TYK2/JAK1 Inhibitor
Brepocitinib for Dermatomyositis
Recruiting1 awardPhase 3
Orlando, Florida
This trial tests brepocitinib, a drug that blocks inflammation-causing proteins, in adults with dermatomyositis. The goal is to see if it improves symptoms like muscle weakness and skin rashes by reducing inflammation. Another similar drug has shown positive results in treating difficult cases of dermatomyositis.
Monoclonal Antibodies
Dazukibart for Myositis
Recruiting2 awardsPhase 3
Beckley, West Virginia
This trial is studying a medicine called dazukibart in people with muscle disorders called idiopathic inflammatory myopathies. These disorders cause muscle inflammation and weakness, making it hard for patients to do
Trials With No Placebo
Procedure
Sodium Thiosulfate for Calcinosis
Recruiting1 awardPhase 2
Pittsburgh, Pennsylvania
This trial aims to test the safety and effectiveness of injecting STS directly into calcinosis lesions in patients with certain autoimmune diseases. The injection process will be guided by ultrasound, and the effects on lesion
CAR T-cell Therapy
CAR T Therapy for Dermatomyositis
Recruiting1 awardPhase 1
Stanford, California
This trial tests a new therapy in adults with dermatomyositis. The therapy modifies their white blood cells to target and destroy harmful B cells, aiming to reset their immune system and reduce disease symptoms. This new treatment shows promising results in similar conditions.
Monoclonal Antibodies
Efgartigimod SC for Myositis
Recruiting2 awardsPhase 3
Beverly Hills, California
This trial aims to check the safety and effectiveness of an injectable medication called efgartigimod PH20 SC in adults with muscle inflammation who participated in an earlier phase. The medication works by reducing harmful proteins that cause muscle problems.
Monoclonal Antibodies
Dazukibart for Myositis
Recruiting2 awardsPhase 3
Beckley, West Virginia
This trial is studying a medicine called dazukibart in people with muscle disorders called idiopathic inflammatory myopathies. These disorders cause muscle inflammation and weakness, making it hard for patients to do
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.