Retinal Imaging for Neurodegenerative Disease
Recruiting1 award2 criteria
Durham, North Carolina
This trial uses special cameras to take detailed pictures of the back of the eye in people with cognitive impairments or neurodegenerative diseases. Researchers analyze these images to find early signs of these diseases by examining tiny blood vessels in the eye.
Behavioral Intervention
Spatial Training for Down Syndrome
Recruiting0 awards3 criteria
Tuscaloosa, Alabama
This trial is testing whether people with Down Syndrome have difficulties with spatial abilities, and if providing them intentional experience with spatial activities can help improve those abilities.
Central Nervous System Stimulant
Methylphenidate for Intellectual Disability and ADHD
Recruiting1 awardPhase 1
Sacramento, California
This trialstudies the effects of medication on cognition in kids & teens with intellectual disability and ADHD. 68 participants will receive drug or placebo in a 1:1 ratio, monitored and assessed for 5 weeks.
Popular Filters
Trials for DS Patients
Anti-metabolites
Uproleselan + Chemotherapy for Leukemia
Recruiting1 awardPhase 1
Philadelphia, Pennsylvania
This trial tests a new drug called uproleselan combined with two chemotherapy drugs in patients whose leukemia has come back or doesn't respond to treatment. Uproleselan helps make the cancer cells more vulnerable to chemotherapy by preventing them from hiding in the bone marrow.
Neurostimulation Device
Hypoglossal Nerve Stimulation for Down Syndrome
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial will follow 57 adolescents and young adults with Down syndrome, moderate to severe sleep apnea, and post-adenotonsillectomy, for 12 months after they receive an implant of the Inspire Upper Airway Stimulation (UAS) System. The goal is to see if there is objective change in cognition and expressive language after implant and therapy with the Inspire UAS System.
Behavioral Intervention
Family-Informed Intervention for Obstructive Sleep Apnea in Children with Down Syndrome
Recruiting1 award4 criteria
Cincinnati, Ohio
This trial will compare a family-informed intervention to standard care for children with obstructive sleep apnea and Down Syndrome, to see if the intervention is more effective over a 12 month period.
Trials for Obstructive Sleep Apnea Patients
Neurostimulation Device
Hypoglossal Nerve Stimulation for Down Syndrome
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial will follow 57 adolescents and young adults with Down syndrome, moderate to severe sleep apnea, and post-adenotonsillectomy, for 12 months after they receive an implant of the Inspire Upper Airway Stimulation (UAS) System. The goal is to see if there is objective change in cognition and expressive language after implant and therapy with the Inspire UAS System.
Behavioral Intervention
Family-Informed Intervention for Obstructive Sleep Apnea in Children with Down Syndrome
Recruiting1 award4 criteria
Cincinnati, Ohio
This trial will compare a family-informed intervention to standard care for children with obstructive sleep apnea and Down Syndrome, to see if the intervention is more effective over a 12 month period.
Procedure
Atomoxetine + Oxybutynin for Sleep Apnea in Down Syndrome
Recruiting1 awardPhase 2
Tucson, Arizona
This trial tests a combination of two medications, atomoxetine and oxybutynin, in children with Down syndrome and sleep apnea. The goal is to see if these medications can improve their breathing during sleep over several months. The study will measure changes in sleep quality and overall health. Atomoxetine is a nonstimulant medication used for ADHD and generally has fewer negative effects on sleep compared to other treatments.
Trials With No Placebo
Anti-metabolites
Uproleselan + Chemotherapy for Leukemia
Recruiting1 awardPhase 1
Philadelphia, Pennsylvania
This trial tests a new drug called uproleselan combined with two chemotherapy drugs in patients whose leukemia has come back or doesn't respond to treatment. Uproleselan helps make the cancer cells more vulnerable to chemotherapy by preventing them from hiding in the bone marrow.
Neurostimulation Device
Hypoglossal Nerve Stimulation for Down Syndrome
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial will follow 57 adolescents and young adults with Down syndrome, moderate to severe sleep apnea, and post-adenotonsillectomy, for 12 months after they receive an implant of the Inspire Upper Airway Stimulation (UAS) System. The goal is to see if there is objective change in cognition and expressive language after implant and therapy with the Inspire UAS System.
Behavioral Intervention
Family-Informed Intervention for Obstructive Sleep Apnea in Children with Down Syndrome
Recruiting1 award4 criteria
Cincinnati, Ohio
This trial will compare a family-informed intervention to standard care for children with obstructive sleep apnea and Down Syndrome, to see if the intervention is more effective over a 12 month period.
Behavioural Intervention
PIXI for Neurogenetic Disorders
Recruiting1 award2 criteria
Research Triangle Park, North Carolina
This trial tests a program called PIXI, which helps parents of infants with genetic disorders. The program educates parents about their baby's condition, coaches them on how to interact with their baby, and provides family support. The goal is to improve the baby's development and family well-being.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.