Antisense Oligonucleotide
Daplusiran/Tomligisiran + Bepirovirsen for Chronic Hepatitis B
Recruiting0 awardsPhase 2
San Francisco, California
This trial aims to test the effectiveness and safety of two different doses of a drug combination (DAP/TOM) followed by another drug (bepirovirsen) in people with chronic hepatitis B
Antiviral
JNJ-73763989 + Antivirals for Hepatitis B and D Co-Infection
Recruiting0 awardsPhase 2
Redwood City, California
This trial is testing a new drug called JNJ-73763989 combined with an existing medication to treat hepatitis D virus (HDV). The goal is to see if this combination works better than the current treatment alone. The new drug is expected to enhance the effectiveness of the existing medication.
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Trials for HBV Patients
TLR8 Agonist
Selgantolimod for Chronic Hepatitis B and HIV
Recruiting0 awardsPhase 2
San Diego, California
This trial tests a pill called Selgantolimod in patients with chronic hepatitis B and HIV who have been on antiviral therapy for an extended period. The pill aims to activate the immune system to reduce the hepatitis B virus levels in their blood.
Trials for Chronic Hepatitis B Patients
Nucleos(t)ide Analogue
AB-729 + Pegylated Interferon for Chronic Hepatitis B
Recruiting1 awardPhase 2
Hillsborough, New Jersey
This trial is testing a new drug called AB-729 for patients with Chronic Hepatitis B. It is used along with existing treatments to lower virus levels, manage the virus, and boost the immune system.
Virus Therapy
VIR-2218 + VIR-3434 + PEG-IFNα for Chronic Hepatitis B
Recruiting1 awardPhase 2
San Francisco, California
This trial involves testing three treatments (VIR-2218, VIR-3434, and PEG-IFNα) on patients with chronic hepatitis B. The goal is to see if these treatments are safe, can be tolerated by patients, and are effective in reducing the virus. The treatments work by either lowering the virus levels or boosting the immune system to fight the virus. Peginterferon alpha (PEG-IFNα) has been used to treat chronic hepatitis B by modulating the immune system, often in combination with other medications for enhanced efficacy.
Nucleoside Reverse Transcriptase Inhibitor
TAF for Chronic Hepatitis B
Recruiting0 awardsPhase 2
Los Angeles, California
This trial is testing a new drug, tenofovir alafenamide, to see if it is safe and effective in treating children and adolescents with chronic hepatitis B. The trial will consist of two parts, with the first part focused on collecting information about the new drug's pharmacokinetics in children, and the second part testing the safety and efficacy of the drug in children with chronic hepatitis B.
NA therapy
Stopping Antiviral Therapy for Chronic Hepatitis B
Recruiting1 award
San Francisco, California
This trial is for patients with the early antigen negative form of chronic hepatitis B who have been on antiviral drugs for at least 192 weeks. The trial offers the option to stop or continue treatment to see if there are any clinical differences and what the mechanisms and gene expression profiles are that correlate with the clinical course.
Trials With No Placebo
Rapid Screening for Hepatitis C & B
Recruiting3 awardsPhase 4
Toronto, Ontario
This trial aims to study the effectiveness of rapid screening methods in diagnosing viral hepatitis infections compared to traditional methods. The goal is to provide same-day results to improve diagnosis rates and help healthcare providers engage with
Nucleos(t)ide Analogue
AB-729 + Pegylated Interferon for Chronic Hepatitis B
Recruiting1 awardPhase 2
Hillsborough, New Jersey
This trial is testing a new drug called AB-729 for patients with Chronic Hepatitis B. It is used along with existing treatments to lower virus levels, manage the virus, and boost the immune system.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.