Behavioural Intervention
HPV Education Interventions for Health Personnel Attitudes
Recruiting1 award
Las Cruces, New Mexico
This trial will compare two interventions to see which is more effective at reducing HPV vaccine hesitancy and increasing uptake and completion among people living in the El Paso U.S.-Mexico Border Region.
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Trials for HPV Patients
CAR T-cell Therapy
E7 TCR T Cell Therapy for HPV-Related Cancers
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial is testing a new therapy for HPV-associated cancers. Researchers will take a person's blood, remove certain white blood cells, and insert genes that make them to target cancer cells that have the HPV protein called E7. The genetically changed cells, called E7 TCR cells, are then given back to the person to fight the cancer.
Trials for OPC Patients
Platinum-based Chemotherapy
Reduced Radiation + Chemotherapy for Oral Squamous Cell Carcinoma
Recruiting1 awardPhase 2
Basking Ridge, New Jersey
This trial is comparing a less intense radiation therapy with 2 cycles of standard chemotherapy to the current standard chemoradiation for people with HPV positive and hypoxia negative T1-2, N1-2c oropharyngeal squamous cell carcinoma.
CAR T-cell Therapy
E7 TCR-T Cells for HPV-Related Cervical and Throat Cancer
Recruiting1 awardPhase 2
New Brunswick, New Jersey
This trial tests a new treatment using modified immune cells to fight cancers caused by HPV. It targets patients with specific types of cancer linked to HPV who have a certain genetic marker. The treatment works by reprogramming the patient's immune cells to attack the cancer cells.
Cancer Vaccine
PDS0101 Vaccine + Pembrolizumab for Oropharyngeal Cancer
Recruiting2 awardsPhase 1 & 2
Rochester, Minnesota
This trial is studying PDS0101, a vaccine made from specific peptides, either alone or in combination with pembrolizumab, to see how well it works in treating patients with human papillomavirus-associated oropharynx cancer that has spread to nearby tissue or lymph nodes.
Radiation Therapy
SABR Boost + Short-course Radiation for Oropharyngeal Cancer
Recruiting1 awardPhase 2
Montreal, Quebec
This trial is testing whether a shorter, more intense course of radiation therapy is as effective as the standard 7-week course for treating oropharynx cancer associated with the human papillomavirus.
Trials for P16 Positive Patients
Radiation Therapy
SABR Boost + Short-course Radiation for Oropharyngeal Cancer
Recruiting1 awardPhase 2
Montreal, Quebec
This trial is testing whether a shorter, more intense course of radiation therapy is as effective as the standard 7-week course for treating oropharynx cancer associated with the human papillomavirus.
Histone Deacetylase Inhibitor
Combination Immunotherapy for Human Papillomavirus & Colorectal Cancer
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial is testing a new combination drug treatment for people with metastatic HPV-associated cancers or microsatellite stable small bowel or colorectal cancer.
Trials With No Placebo
Platinum-based Chemotherapy
Reduced Radiation + Chemotherapy for Oral Squamous Cell Carcinoma
Recruiting1 awardPhase 2
Basking Ridge, New Jersey
This trial is comparing a less intense radiation therapy with 2 cycles of standard chemotherapy to the current standard chemoradiation for people with HPV positive and hypoxia negative T1-2, N1-2c oropharyngeal squamous cell carcinoma.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.