GLP-1 Receptor Agonist
Semaglutide for HIV-Associated Lipohypertrophy
Recruiting2 awardsPhase 2
Cleveland, Ohio
This trial tests semaglutide, a medication that controls blood sugar, in people with HIV who have abnormal fat accumulation. It aims to see if the drug can reduce fat, improve blood vessel function, and lower inflammation. Semaglutide has been used to improve blood sugar levels and reduce body weight in individuals with obesity and type 2 diabetes.
Photobiomodulation
Laser Light Therapy for Pediatric Sleep Apnea
Recruiting0 awards3 criteria
Edmonton, Alberta
This trial is testing a laser light therapy called photobiomodulation (PBM) to help children with obstructive sleep apnea and swollen tonsils. PBM aims to reduce swelling and improve breathing without the need for surgery.
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Trials for Hypertrophic Cardiomyopathy Patients
Long-term Safety of Aficamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 2 & 3
San Francisco, California
This trial is focused on collecting data about the safety and tolerability of a new medication called aficamten. The study involves people who are using this medication to see if it remains safe and well-tolerated over an extended period.
Behavioral Intervention
Exercise Program for Hypertrophic Cardiomyopathy
Recruiting1 award6 criteria
San Francisco, California
This trial will compare the effects of moderate exercise vs. usual activity on improving symptoms and cardiac function in people with HCM. 70 participants will be monitored over 24 weeks.
Myosin Inhibitor
Aficamten vs Metoprolol for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
Anchorage, Alaska
This trial compares a new drug, aficamten, with a common heart medication, metoprolol succinate, in adults with a specific heart condition that causes symptoms and blood flow blockage. Aficamten helps the heart muscle relax, while metoprolol succinate slows and eases the heart's pumping. Metoprolol has been widely used since 1975.
Myosin Inhibitor
Mavacamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
La Jolla, California
This trial is testing a new medication called mavacamten to see if it is safe and effective for people with a heart condition that makes their heart muscle too thick. The goal is to help their heart work better and improve their symptoms.
Trials for HCM Patients
Long-term Safety of Aficamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 2 & 3
San Francisco, California
This trial is focused on collecting data about the safety and tolerability of a new medication called aficamten. The study involves people who are using this medication to see if it remains safe and well-tolerated over an extended period.
Behavioral Intervention
Exercise Program for Hypertrophic Cardiomyopathy
Recruiting1 award6 criteria
San Francisco, California
This trial will compare the effects of moderate exercise vs. usual activity on improving symptoms and cardiac function in people with HCM. 70 participants will be monitored over 24 weeks.
Myosin Inhibitor
Aficamten vs Metoprolol for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
Anchorage, Alaska
This trial compares a new drug, aficamten, with a common heart medication, metoprolol succinate, in adults with a specific heart condition that causes symptoms and blood flow blockage. Aficamten helps the heart muscle relax, while metoprolol succinate slows and eases the heart's pumping. Metoprolol has been widely used since 1975.
Myosin Inhibitor
Mavacamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
La Jolla, California
This trial is testing a new medication called mavacamten to see if it is safe and effective for people with a heart condition that makes their heart muscle too thick. The goal is to help their heart work better and improve their symptoms.
Phase 3 Trials
Long-term Safety of Aficamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 2 & 3
San Francisco, California
This trial is focused on collecting data about the safety and tolerability of a new medication called aficamten. The study involves people who are using this medication to see if it remains safe and well-tolerated over an extended period.
Myosin Inhibitor
Aficamten vs Metoprolol for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
Anchorage, Alaska
This trial compares a new drug, aficamten, with a common heart medication, metoprolol succinate, in adults with a specific heart condition that causes symptoms and blood flow blockage. Aficamten helps the heart muscle relax, while metoprolol succinate slows and eases the heart's pumping. Metoprolol has been widely used since 1975.
Myosin Inhibitor
Mavacamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
La Jolla, California
This trial is testing a new medication called mavacamten to see if it is safe and effective for people with a heart condition that makes their heart muscle too thick. The goal is to help their heart work better and improve their symptoms.
Aficamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 3
Anchorage, Alaska
This trial is testing aficamten, a medication that may help people with a thickened heart muscle condition. It aims to improve their quality of life and ability to exercise. The drug works by making the heart muscle less stiff, which could help the heart pump blood better.
Trials With No Placebo
Behavioural Intervention
Ultrasound Technology for Detecting Lipohypertrophy in Diabetes
Recruiting1 award
Vancouver, British Columbia
This trial is testing if a new ultrasound technology can detect early signs of lipohypertrophy, and if injecting insulin into these areas affects how insulin is absorbed.
Long-term Safety of Aficamten for Hypertrophic Cardiomyopathy
Recruiting1 awardPhase 2 & 3
San Francisco, California
This trial is focused on collecting data about the safety and tolerability of a new medication called aficamten. The study involves people who are using this medication to see if it remains safe and well-tolerated over an extended period.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.