Behavioral Intervention
Resistance Training for Chronic Kidney Disease
Recruiting1 award2 criteria
Winston-Salem, North Carolina
This trial aims to test whether a 12-week high-velocity resistance training program is safe and practical for older adults with advanced chronic kidney disease. The study will compare this program to a control group attending
Behavioural Intervention
Patient-centered Care for Acute Kidney Injury
Recruiting1 award2 criteria
Birmingham, Alabama
This trial will compare a new intervention to usual care to see if it helps people avoid hospital visits for up to 90 days. It will test how it affects kidney health and patient reported outcomes. 2145 people will be randomly assigned to the study.
NAD+ precursor
NAD Augmentation for Diabetic Kidney Disease
Recruiting0 awardsPhase 2
Boston, Massachusetts
This trial is testing whether NMN, a compound that may improve cell function, can help older adults with type 2 diabetes and high urine protein levels. The goal is to see if NMN can reduce kidney damage by improving cell energy production. Participants will receive NMN to compare the effects.
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Trials for Chronic Kidney Failure Patients
Vitamin D Analog
Calcitriol vs Vitamin D for Kidney Failure
Recruiting1 awardPhase 2
Seattle, Washington
"This trial compares the effects of two different treatments on patients with kidney failure and high levels of parathyroid hormone. One group will receive a fixed dose of oral calcitriol, while the other
SGLT2 Inhibitor
Sotagliflozin for Diabetic Kidney Disease
Recruiting1 awardPhase 3
Stanford, California
This trial aims to test the effects of a new drug called SOTA on kidney function in people with type 1 diabetes and moderate to advanced kidney disease. Previous studies have shown that SOTA can increase
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Empagliflozin for Kidney Failure
Recruiting1 awardPhase 1 & 2
Jackson, Mississippi
This trial will test the safety of empagliflozin in dialysis patients; results may lead to a larger clinical trial to explore the potential heart benefits of empagliflozin.
Fingolimod for Kidney Transplant Rejection
Recruiting1 awardPhase 2
Houston, Texas
This trial tests if fingolimod can help new kidney transplant patients by preventing kidney damage and improving transplant success. Fingolimod works by blocking harmful pathways in the body. The study aims to see if this treatment is safe and effective over time. Fingolimod has been used in multiple sclerosis treatment and is known for its immunomodulating effects, but it has significant potential side effects.
Behavioural Intervention
Communication Tool Training for Kidney Failure
Recruiting1 award3 criteria
Baltimore, Maryland
This trial will test whether the "Best Case/Worse Case" communication tool can help patients with end-stage renal disease receive appropriate palliative care and improve communication between patients and their caregivers.
Trials for CKD Patients
Vitamin D Analog
Calcitriol vs Vitamin D for Kidney Failure
Recruiting1 awardPhase 2
Seattle, Washington
"This trial compares the effects of two different treatments on patients with kidney failure and high levels of parathyroid hormone. One group will receive a fixed dose of oral calcitriol, while the other
SGLT2 Inhibitor
Sotagliflozin for Diabetic Kidney Disease
Recruiting1 awardPhase 3
Stanford, California
This trial aims to test the effects of a new drug called SOTA on kidney function in people with type 1 diabetes and moderate to advanced kidney disease. Previous studies have shown that SOTA can increase
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Empagliflozin for Kidney Failure
Recruiting1 awardPhase 1 & 2
Jackson, Mississippi
This trial will test the safety of empagliflozin in dialysis patients; results may lead to a larger clinical trial to explore the potential heart benefits of empagliflozin.
Fingolimod for Kidney Transplant Rejection
Recruiting1 awardPhase 2
Houston, Texas
This trial tests if fingolimod can help new kidney transplant patients by preventing kidney damage and improving transplant success. Fingolimod works by blocking harmful pathways in the body. The study aims to see if this treatment is safe and effective over time. Fingolimod has been used in multiple sclerosis treatment and is known for its immunomodulating effects, but it has significant potential side effects.
Behavioural Intervention
Communication Tool Training for Kidney Failure
Recruiting1 award3 criteria
Baltimore, Maryland
This trial will test whether the "Best Case/Worse Case" communication tool can help patients with end-stage renal disease receive appropriate palliative care and improve communication between patients and their caregivers.
Phase 3 Trials
SGLT2 Inhibitor
Sotagliflozin for Diabetic Kidney Disease
Recruiting1 awardPhase 3
Stanford, California
This trial aims to test the effects of a new drug called SOTA on kidney function in people with type 1 diabetes and moderate to advanced kidney disease. Previous studies have shown that SOTA can increase
Behavioral Intervention
Self-Managed Blood Pressure Control for Chronic Kidney Disease
Recruiting2 awardsPhase 3
Iowa City, Iowa
This trial will test if patients can better manage their blood pressure with the help of a clinical pharmacist and if this lowers their blood pressure more than the standard care.
Trials With No Placebo
Vitamin D Analog
Calcitriol vs Vitamin D for Kidney Failure
Recruiting1 awardPhase 2
Seattle, Washington
"This trial compares the effects of two different treatments on patients with kidney failure and high levels of parathyroid hormone. One group will receive a fixed dose of oral calcitriol, while the other
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Empagliflozin for Kidney Failure
Recruiting1 awardPhase 1 & 2
Jackson, Mississippi
This trial will test the safety of empagliflozin in dialysis patients; results may lead to a larger clinical trial to explore the potential heart benefits of empagliflozin.
Behavioural Intervention
Communication Tool Training for Kidney Failure
Recruiting1 award3 criteria
Baltimore, Maryland
This trial will test whether the "Best Case/Worse Case" communication tool can help patients with end-stage renal disease receive appropriate palliative care and improve communication between patients and their caregivers.
Behavioural Intervention
Communication Intervention for Dementia
Recruiting1 award12 criteria
Seattle, Washington
This trial is testing whether or not the Jumpstart intervention can improve patient-centered outcomes for those with chronic illness. The study will specifically look at Alzheimer's disease and related dementias, but will also include other common chronic illnesses. The trial will assess the efficacy of the intervention by measuring quality of care, intensity of care outcomes, and patient- and family-reported outcomes. There will also be a mixed-methods evaluation of the implementation of the intervention to explore barriers and facilitators to future implementation and dissemination.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.