SGLT2 Inhibitor
Zibotentan + Dapagliflozin for Liver Cirrhosis
Recruiting0 awardsPhase 2
Birmingham, Alabama
This trial is testing a combination of two drugs, zibotentan and dapagliflozin, and also dapagliflozin alone. It targets people with liver disease (cirrhosis) that causes high blood pressure in the liver's veins. The treatment aims to lower this high blood pressure and improve liver health. Dapagliflozin is a medication that has been shown to reduce cardiovascular death and heart failure.
Behavioural Intervention
Communication Intervention for Dementia
Recruiting1 award12 criteria
Seattle, Washington
This trial is testing whether or not the Jumpstart intervention can improve patient-centered outcomes for those with chronic illness. The study will specifically look at Alzheimer's disease and related dementias, but will also include other common chronic illnesses. The trial will assess the efficacy of the intervention by measuring quality of care, intensity of care outcomes, and patient- and family-reported outcomes. There will also be a mixed-methods evaluation of the implementation of the intervention to explore barriers and facilitators to future implementation and dissemination.
Cholates for Liver Disease
Recruiting1 awardPhase 2
Dallas, Texas
This trial aims to improve the evaluation of patients with advanced liver disease. Currently, the assessment is limited to imaging, liver function tests, and liver biopsy. However, with advancements in treatments and liver transplantation
Plasma Expander
Albumin for Liver Cirrhosis
Recruiting0 awardsPhase 2
West Haven, Connecticut
This trial aims to study the effects of albumin on increasing urine production in patients with liver disease and fluid retention. It will also look at how albumin may help prevent complications like kidney injury after treatment
Procedure
TIPS Procedure for Liver Cirrhosis and Muscle Loss
Recruiting1 awardPhase < 1
Portland, Oregon
This trial will test whether TIPS creation leads to improved muscle mass, body composition and muscle function within the first 12 months after the procedure compared to a control group without TIPS, and whether these changes improve liver disease outcomes in patients awaiting liver transplantation.
Popular Filters
Trials for Hepatocellular Carcinoma Patients
Procedure
Histotripsy with HistoSonics System for Liver Cancer
Recruiting1 award1 criteria
Miami, Florida
This trial tests a device that uses sound waves to break down liver tumors. It targets patients with liver tumors that may not respond to other treatments. The device works by creating bubbles in the tumor, which then burst and destroy the tumor cells.
Procedure
Anticoagulant Flush for Abdominal Cancer
Recruiting1 award6 criteria
Cleveland, Ohio
This trial is comparing the amount and quality of tissue obtained by endoscopic ultrasound-guided fine needle biopsy when the device is flushed with an anticoagulant or saline solution, as well as the use of a microsieve.
Trials for Liver Cancer Patients
Procedure
Histotripsy with HistoSonics System for Liver Cancer
Recruiting1 award1 criteria
Miami, Florida
This trial tests a device that uses sound waves to break down liver tumors. It targets patients with liver tumors that may not respond to other treatments. The device works by creating bubbles in the tumor, which then burst and destroy the tumor cells.
Procedure
Anticoagulant Flush for Abdominal Cancer
Recruiting1 award6 criteria
Cleveland, Ohio
This trial is comparing the amount and quality of tissue obtained by endoscopic ultrasound-guided fine needle biopsy when the device is flushed with an anticoagulant or saline solution, as well as the use of a microsieve.
Virus Therapy
Viral Therapy for Liver Cancer
Recruiting2 awardsPhase 1
Scottsdale, Arizona
This trial is studying a new virus that has been genetically engineered to produce interferon beta, which may help to treat patients with liver cancer or other solid tumors that have spread to other parts of the body and are not responding to treatment.
Phase 3 Trials
Statin
Simvastatin for Liver Cirrhosis
Recruiting1 awardPhase 3
San Francisco, California
This trial tests if simvastatin can prevent serious liver problems in U.S. Veterans with early-stage liver damage. Simvastatin not only lowers cholesterol but also helps protect the liver from further damage and reduces the risk of severe liver issues. Statins, including simvastatin, have been increasingly recognized for their potential benefits in treating chronic liver diseases, including cirrhosis, by reducing portal pressure and protecting against liver damage.
Procedure
PCEA vs IV PCA for Postoperative Pain Management After Liver Surgery
Recruiting2 awardsPhase 3
Basking Ridge, New Jersey
This trial will compare patient-controlled epidural analgesia (PCEA) to the current standard of care, IV PCA, to see if PCEA is a better method for managing pain after liver resection.
Anti-fibrinolytic agent
TXA for Bleeding in Liver Surgery
Recruiting1 awardPhase 3
Rochester, Minnesota
This trial will evaluate the impact of tranexamic acid on perioperative blood transfusion in patients undergoing liver resection. TXA is given to help prevent or treat excessive bleeding. The study will enroll 1230 participants.
Trials With No Placebo
Procedure
Histotripsy with HistoSonics System for Liver Cancer
Recruiting1 award1 criteria
Miami, Florida
This trial tests a device that uses sound waves to break down liver tumors. It targets patients with liver tumors that may not respond to other treatments. The device works by creating bubbles in the tumor, which then burst and destroy the tumor cells.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.