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15 Lynch Syndrome Trials
Power is an online platform that helps thousands of Lynch Syndrome patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
STK-012 + Pembrolizumab for Cancer
Columbus, OhioKey Eligibility Criteria
Chemotherapy + Atezolizumab for Colon Cancer
Columbus, OhioCancer Vaccines for Lynch Syndrome
Columbus, OhioKey Eligibility Criteria
DNA Sequencing for Endometrial Cancer
Columbus, OhioChemotherapy +/− Bevacizumab for Stage II Colon Cancer
Columbus, OhioPembrolizumab for Pediatric Brain Cancer
Cincinnati, OhioRP1 + Nivolumab for Cancer
Cincinnati, OhioKey Eligibility Criteria
NC410 + Pembrolizumab for Advanced Cancer
Cincinnati, OhioRegorafenib + Pembrolizumab for Colorectal Cancer
Cleveland, OhioKey Eligibility Criteria
Combination Immunotherapy for Cancer
Cleveland, OhioKey Eligibility Criteria
Pancreatic Cancer Screening for Pancreatic Cancer
Cleveland, OhioKey Eligibility Criteria
Niraparib + Dostarlimab for Colorectal Cancer
Pittsburgh, PennsylvaniaINCB 99280 + Ipilimumab for Solid Cancers
Detroit, MichiganKFA115 + Tislelizumab for Advanced Cancers
Pittsburgh, PennsylvaniaKey Eligibility Criteria
TIL Therapy for Advanced Cancer
Pittsburgh, PennsylvaniaKey Eligibility Criteria
Frequently Asked Questions
How much do Lynch Syndrome clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Lynch Syndrome clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Lynch Syndrome trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Lynch Syndrome is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Lynch Syndrome medical study ?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Lynch Syndrome clinical trials ?
Most recently, we added Niraparib + Dostarlimab for Colorectal Cancer, Regorafenib + Pembrolizumab for Colorectal Cancer and INCB 99280 + Ipilimumab for Solid Cancers to the Power online platform.