Serotonin (5-HT) 1F Receptor Agonist
Lasmiditan for Pediatric Migraine
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing if lasmiditan is safe and effective for children aged 6 to 17 with migraines. The medication aims to block brain signals that cause migraine pain. The study will last several months and may include a few visits. Lasmiditan has been shown to be effective in treating acute migraine attacks in adults and is noted for its safety profile, particularly due to its lack of vasoconstrictive effects.
Monoclonal Antibodies
Erenumab for Migraine
Recruiting1 awardPhase 3
Colorado Springs, Colorado
This trial tests if erenumab, an injection given regularly, can reduce migraine days in children and adolescents with chronic migraines by blocking a protein that triggers these headaches. Erenumab has been shown to reduce migraine days and improve quality of life in adults with chronic and episodic migraines.
Popular Filters
Trials for Migraine Patients
Behavioral Intervention
CBT + Amitriptyline for Childhood Migraine
Recruiting1 award4 criteria
Birmingham, Alabama
This trial will compare Cognitive Behavioral Therapy (CBT) via telehealth with a pill-based preventive therapy (amitriptyline) for treating childhood migraine. Results will help provide evidence-based, accessible care.
Behavioral Intervention
Emotional Awareness and Expression Therapy for Migraine
Recruiting1 award
Salt Lake City, Utah
This trial tests a new therapy called Emotional Awareness and Expression Therapy (EAET) for people with migraines. EAET helps individuals recognize and express difficult emotions to reduce stress and emotional pain. The goal is to see if this therapy can lower the frequency and severity of migraine attacks.
Behavioral Intervention
Mind-Body Balance for Pediatric Migraine
Recruiting1 award5 criteria
Aurora, Colorado
This trial is testing a mind-body intervention delivered by a nurse, using different doses of three treatment components, to find the combination that works best to reduce the number of headache days.
Trials for MA Patients
Behavioral Intervention
CBT + Amitriptyline for Childhood Migraine
Recruiting1 award4 criteria
Birmingham, Alabama
This trial will compare Cognitive Behavioral Therapy (CBT) via telehealth with a pill-based preventive therapy (amitriptyline) for treating childhood migraine. Results will help provide evidence-based, accessible care.
Behavioral Intervention
Emotional Awareness and Expression Therapy for Migraine
Recruiting1 award
Salt Lake City, Utah
This trial tests a new therapy called Emotional Awareness and Expression Therapy (EAET) for people with migraines. EAET helps individuals recognize and express difficult emotions to reduce stress and emotional pain. The goal is to see if this therapy can lower the frequency and severity of migraine attacks.
Behavioral Intervention
Mind-Body Balance for Pediatric Migraine
Recruiting1 award5 criteria
Aurora, Colorado
This trial is testing a mind-body intervention delivered by a nurse, using different doses of three treatment components, to find the combination that works best to reduce the number of headache days.
Phase 3 Trials
Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonist
Rimegepant for Pediatric Migraine
Recruiting2 awardsPhase 3
Anaheim, California
This trial aims to test the safety of rimegepant, a medication for treating migraines. The study focuses on children and adolescents aged 6 to 17 years who experience moderate to severe migraines. Rimegepant works by blocking a protein that triggers migraine pain, helping to alleviate symptoms.
Calcitonin Gene-Related Peptide (CGRP) Antagonist
Atogepant for Migraine Prevention
Recruiting2 awardsPhase 3
Phoenix, Arizona
This trial is testing a medication called Atogepant to see if it can safely and effectively prevent migraines in people who have them often. The medication works by blocking signals in the brain that cause migraines. Atogepant is a newly approved oral medication for the prevention of episodic migraine.
Monoclonal Antibodies
Fremanezumab for Preventing Migraine in Children and Adolescents
Recruiting2 awardsPhase 3
Colorado Springs, Colorado
This trial is testing an injectable medication called fremanezumab to prevent migraines in children and teenagers aged 6 to 17. The medication works by blocking signals in the brain that cause headaches. Fremanezumab has been investigated for the preventive treatment of migraine in adults.
Trials With No Placebo
Behavioral Intervention
CBT + Amitriptyline for Childhood Migraine
Recruiting1 award4 criteria
Birmingham, Alabama
This trial will compare Cognitive Behavioral Therapy (CBT) via telehealth with a pill-based preventive therapy (amitriptyline) for treating childhood migraine. Results will help provide evidence-based, accessible care.
Behavioral Intervention
Emotional Awareness and Expression Therapy for Migraine
Recruiting1 award
Salt Lake City, Utah
This trial tests a new therapy called Emotional Awareness and Expression Therapy (EAET) for people with migraines. EAET helps individuals recognize and express difficult emotions to reduce stress and emotional pain. The goal is to see if this therapy can lower the frequency and severity of migraine attacks.
Behavioral Intervention
Mind-Body Balance for Pediatric Migraine
Recruiting1 award5 criteria
Aurora, Colorado
This trial is testing a mind-body intervention delivered by a nurse, using different doses of three treatment components, to find the combination that works best to reduce the number of headache days.
Behavioral Intervention
Online Intervention for Migraines
Recruiting1 awardPhase 2
Cincinnati, Ohio
This trial is testing whether an online intervention can help improve headache outcomes for adolescents with migraines, compared to an attention control intervention. The primary outcome will be the number of headache days, assessed via online daily diary pre- and post-intervention.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.