Alpha-1 Agonist
Abdominal Compression for Orthostatic Hypotension
Recruiting0 awardsPhase 1
Nashville, Tennessee
This trial will help determine how compression garments help autonomic failure patients with orthostatic hypotension by testing how well they improve blood pressure and tolerance to standing up.
Popular Filters
Trials for MSA Patients
Gene Therapy
GDNF Gene Therapy for Multiple System Atrophy
Recruiting0 awardsPhase 1
Irvine, California
This trial is testing a new gene therapy for people with Multiple System Atrophy (MSA). The therapy uses a harmless virus to deliver a gene into the brain, which then produces a protein that helps protect brain cells. The goal is to see if this treatment is safe and if it can help slow down the progression of MSA.
Device
Midodrine vs Abdominal Compression for Orthostatic Hypotension
Recruiting0 awardsPhase < 1
Nashville, Tennessee
This trial is testing two interventions for low blood pressure when standing up. It will last for five days total, and screen and test participants at Vanderbilt University Medical Center.
[18F]FDOPA Imaging for Parkinson's Disease
Recruiting1 awardPhase 1
Nashville, Tennessee
This trial is testing a biomarker that may predict which patients with Pure Autonomic Failure (PAF) will convert to Parkinson's disease (PD), Multiple System Atrophy (MSA), or Dementia with Lewy Bodies (DLB). The biomarker is related to the neurotransmitter dopamine.
Bisphosphonate
Zoledronic Acid for Parkinson's Disease
Recruiting2 awardsPhase 4
Scottsdale, Arizona
This trial is testing whether a single infusion of zoledronic acid can help prevent fractures in people with Parkinson's disease or parkinsonism. A total of 3500 participants will be enrolled in the United States.
Device
Automated Abdominal Binder for Orthostatic Hypotension
Recruiting0 awardsPhase 1 & 2
Nashville, Tennessee
This trial is testing a special belt that inflates to help people with low blood pressure when they stand up. It targets patients who have a condition that makes it hard for them to keep their blood pressure stable. The belt works by squeezing the abdomen to help keep blood flowing properly when standing.
Trials for PD Patients
Device
Midodrine vs Abdominal Compression for Orthostatic Hypotension
Recruiting0 awardsPhase < 1
Nashville, Tennessee
This trial is testing two interventions for low blood pressure when standing up. It will last for five days total, and screen and test participants at Vanderbilt University Medical Center.
[18F]FDOPA Imaging for Parkinson's Disease
Recruiting1 awardPhase 1
Nashville, Tennessee
This trial is testing a biomarker that may predict which patients with Pure Autonomic Failure (PAF) will convert to Parkinson's disease (PD), Multiple System Atrophy (MSA), or Dementia with Lewy Bodies (DLB). The biomarker is related to the neurotransmitter dopamine.
Bisphosphonate
Zoledronic Acid for Parkinson's Disease
Recruiting2 awardsPhase 4
Scottsdale, Arizona
This trial is testing whether a single infusion of zoledronic acid can help prevent fractures in people with Parkinson's disease or parkinsonism. A total of 3500 participants will be enrolled in the United States.
Procedure
Sural Nerve Graft for Parkinson's Disease
Recruiting0 awardsPhase 1
Lexington, Kentucky
This trial aims to test the safety and feasibility of implanting a person's own nerve tissue into a specific area of the brain for individuals diagnosed with Parkinson's disease or Multiple System Atrophy. Seven participants
Trials With No Placebo
[18F]FDOPA Imaging for Parkinson's Disease
Recruiting1 awardPhase 1
Nashville, Tennessee
This trial is testing a biomarker that may predict which patients with Pure Autonomic Failure (PAF) will convert to Parkinson's disease (PD), Multiple System Atrophy (MSA), or Dementia with Lewy Bodies (DLB). The biomarker is related to the neurotransmitter dopamine.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.