Local Anesthetic
Exparel for Craniofacial Pain
Recruiting0 awardsPhase 2
Stanford, California
This trial tests if injecting Exparel into the nasal area can help people with craniofacial pain. Exparel is a long-lasting pain reliever, and the study focuses on those who usually get pain relief from Lidocaine during ENT procedures.
Procedure
Lidocaine Patch for Peripheral Neuropathy
Recruiting0 awards6 criteria
Palo Alto, California
This trial will compare a lidocaine patch to a placebo patch to see if the lidocaine patch helps reduce neuropathic pain. Measurements and a visual scale will track pain severity. The study will also assess a hybrid biomarker to distinguish between active and placebo treatments.
Behavioural Intervention
Exercise Intervention for Neuropathic Pain After Spinal Cord Injury
Recruiting1 award1 criteria
Boston, Massachusetts
This trial is studying how functional electrical stimulation (FES) can help people with spinal cord injuries by reducing pain, improving brain function, and increasing the size of the hippocampus.
Deep Brain Stimulation
DBS for Chronic Pain
Recruiting1 award12 criteria
San Francisco, California
This trial is testing a new way to provide deep brain stimulation (DBS) for people with chronic pain that has not been relieved by other treatments. DBS involves surgically placing a small device in the brain that sends electrical signals to specific areas. The goal of this trial is to find out whether DBS is more effective when it is turned on only when needed, rather than continuously.
Popular Filters
Trials for Nerve Pain Patients
Behavioural Intervention
Virtual Reality Self-Hypnosis for Pain Relief
Recruiting1 award2 criteria
New York, New York
This trial is looking at whether a self-hypnosis software, used with a virtual reality device, can help to relieve pain in HIV patients. The study will assess the safety, usability, and effectiveness
Anti-epileptic drug
Gabapentin for Neuropathic Pain in Children
Recruiting1 awardPhase 2
Vancouver, British Columbia
This trial aims to determine how effective gabapentin is in reducing and resolving pain in children with severe brain-based developmental disabilities. These children often experience unexplained periods of pain and irritability, and the
Procedure
Focused Ultrasound for Neuropathic Pain
Recruiting1 award3 criteria
Santa Monica, California
This trial is testing a new treatment that uses sound waves directed at specific parts of the brain to help reduce pain. It targets patients with ongoing neuropathic pain that hasn't been managed well by other treatments. The sound waves aim to improve the function of brain areas that process pain signals. This noninvasive treatment option has shown promise in treating chronic neuropathic pain.
Trials for Diabetic Neuropathy Patients
Cannabinoid
Cannabis Derivatives for Diabetic Neuropathy
Recruiting0 awardsPhase 2
San Diego, California
This trial tests if cannabis derivatives (THC, CBD, and their combination) can reduce chronic diabetic nerve pain in Veterans. Veterans often don't get enough relief from standard treatments, so this study aims to find out if cannabis can help. The trial will test if these cannabis compounds are effective. Cannabis has been studied for its potential to alleviate pain in various conditions, including diabetic neuropathy, but its long-term safety and efficacy remain uncertain.
Neurostimulation Device
Micro-Implantable Pulse Generator for Chronic Pain
Recruiting1 award10 criteria
Scottsdale, Arizona
This trial is testing whether adding peripheral nerve stimulation to conventional medical management is more effective and safe than just using conventional medical management for chronic, intractable peripheral neuralgia that is of post-traumatic or post-surgical origin.
Procedure
RTA 901 for Diabetic Neuropathy
Recruiting0 awardsPhase 2
Phoenix, Arizona
This trial is testing a new drug called RTA 901 to see if it can help people with nerve pain caused by diabetes. The drug likely works by calming down the nerves that are causing the pain. The study will compare different doses of the drug to find out which dose works best.
Non-invasive Brain Stimulation
Noninvasive Brain Stimulation for Diabetic Neuropathy
Recruiting0 awardsPhase 2
Hinsdale, Illinois
This trial is testing a new treatment called non-invasive brain stimulation (ESSTim) for people with pain from diabetic neuropathy. The treatment uses mild electrical signals to change how the brain processes pain. Researchers believe this could be more effective. Non-invasive brain stimulation techniques have been explored for their potential to reduce chronic pain by altering brain activity.
Phase 3 Trials
Topical Analgesic
High-Dose vs Low-Dose Capsaicin for Neuropathic Pain
Recruiting2 awardsPhase 3
La Jolla, California
This trial is testing a new topical pain medication against a low-dose capsaicin control to see if it is more effective and safe in treating moderate to severe post-surgical neuropathic pain.
Glutamate Receptor Antagonist
Basimglurant for Trigeminal Neuralgia
Recruiting0 awardsPhase 2 & 3
La Jolla, California
This trial is testing a medication called basimglurant to see if it can help reduce severe facial pain in adults with Trigeminal Neuralgia. The medication works by blocking a specific receptor in the nervous system to lower pain signals. Researchers will measure changes in pain using patient diaries and feedback.
Peripheral Nerve Stimulation for Neuropathic Pain
Recruiting2 awardsPhase 3
Palo Alto, California
This trial is studying 134 patients with chronic nerve pain in the legs. They will be split into two groups - one receiving standard medical treatment and the other receiving both standard treatment and peripheral nerve stimulation therapy
Trials With No Placebo
Behavioural Intervention
Virtual Reality Self-Hypnosis for Pain Relief
Recruiting1 award2 criteria
New York, New York
This trial is looking at whether a self-hypnosis software, used with a virtual reality device, can help to relieve pain in HIV patients. The study will assess the safety, usability, and effectiveness
Topical Analgesic
High-Dose vs Low-Dose Capsaicin for Neuropathic Pain
Recruiting2 awardsPhase 3
La Jolla, California
This trial is testing a new topical pain medication against a low-dose capsaicin control to see if it is more effective and safe in treating moderate to severe post-surgical neuropathic pain.
NMDA Receptor Antagonist
Ketamine Infusion for Neuralgia
Recruiting3 awardsPhase 4
Rochester, Minnesota
This trial is testing if giving ketamine can help reduce severe nerve pain in patients with brachial plexus injuries. Ketamine works by blocking pain signals to the brain. The study aims to see if this reduces the need for other pain medications. Ketamine has been reported to enhance the pain-relieving effects of local anesthetics and is used primarily for patients who are tolerant to opioids and those with severe acute pain.
Behavioural Intervention
Scrambler Therapy for Neuropathic Pain
Recruiting1 award4 criteria
Baltimore, Maryland
This trial tests if Scrambler Therapy can reduce pain in patients with corticobasal syndrome. The therapy uses electrical signals to trick the brain into feeling non-painful sensations instead of pain. The goal is to see if this treatment can lower pain levels significantly over a short period. Scrambler Therapy is a noninvasive technique that substitutes pain information with non-painful sensations.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.