Behavioural Intervention
Acupuncture for Opioid Use Disorder
Recruiting1 award3 criteria
Bronx, New York
This trial aims to see how patients with chronic pain and opioid use disorder will react to acupuncture treatment and if it affects their mood. The results could help guide future studies for patients considering acupuncture for their conditions
Behavioral Intervention
Mindfulness + Pain Management Visits for Chronic Pain
Recruiting1 award3 criteria
New Brunswick, New Jersey
"This trial aims to see if using Mindfulness-Oriented Recovery Enhancement (MORE) and patient-centered chronic pain management visits can help reduce chronic pain, improve quality of life, and lessen the negative effects
Behavioral Intervention
Smartphone App for Opioid Use Disorder
Recruiting0 awards1 criteria
Kalamazoo, Michigan
This trial aims to see if a smartphone app can help people with opioid use disorder. Participants will use the app to submit videos of themselves taking drug tests. The app also provides reminders, rewards, and
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Trials for Opioid Use Disorder Patients
SIRI Checklist + Peer Coaching for HIV Prevention in Opioid Users
Recruiting1 award
Birmingham, Alabama
This trial will develop and test a checklist to increase evidence-based treatment for rural people who use drugs, including long-acting injectable agents. The hypothesis is that hospital-based care models can successfully engage rural people in effective addiction treatment and infection prevention, which is foundational to Ending the HIV epidemic in rural states.
Behavioural Intervention
Smartphone Apps for Opioid Use Disorder
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial would use apps to help prevent relapse among patients receiving treatment for opioid use disorder. The apps would track the person's location and offer targeted, personalized intervention when they enter an area at high risk for relapse.
Behavioural Intervention
CBD for Opioid Use Disorder
Recruiting0 awardsPhase 2
New York, New York
This trial will test if CBD can help reduce craving and anxiety in people abstaining from heroin. Brain scans will be taken before and after CBD administration to see how it affects neural circuits and transmitters.
Trials for OUD Patients
SIRI Checklist + Peer Coaching for HIV Prevention in Opioid Users
Recruiting1 award
Birmingham, Alabama
This trial will develop and test a checklist to increase evidence-based treatment for rural people who use drugs, including long-acting injectable agents. The hypothesis is that hospital-based care models can successfully engage rural people in effective addiction treatment and infection prevention, which is foundational to Ending the HIV epidemic in rural states.
Behavioural Intervention
Smartphone Apps for Opioid Use Disorder
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial would use apps to help prevent relapse among patients receiving treatment for opioid use disorder. The apps would track the person's location and offer targeted, personalized intervention when they enter an area at high risk for relapse.
Behavioural Intervention
CBD for Opioid Use Disorder
Recruiting0 awardsPhase 2
New York, New York
This trial will test if CBD can help reduce craving and anxiety in people abstaining from heroin. Brain scans will be taken before and after CBD administration to see how it affects neural circuits and transmitters.
Phase 3 Trials
Neuromodulator Medical Device
Bridge Device + Lofexidine for Opioid Use Disorder
Recruiting0 awardsPhase 2 & 3
Baltimore, Maryland
This trial is testing a device called the Bridge Device, which uses electrical signals to help people with opioid addiction. The study focuses on individuals who are not currently on any medication for their addiction. The device aims to ease withdrawal symptoms by sending signals to the brain. Participants will be monitored to see if the device effectively reduces withdrawal symptoms.
Opioid Antagonist
Long-acting Naltrexone for Opioid Addiction
Recruiting4 awardsPhase 3
Towson, Maryland
This trial tests if giving long-lasting naltrexone injections at home can help pre-release prisoners with opioid use disorders stick to their treatment. Naltrexone works by blocking the effects of opioids, making them less appealing. A long-lasting version of naltrexone has been developed and approved in the USA and Russia.
Opioid Analgesic
Pain Medication for Postoperative Pain
Recruiting1 awardPhase 3
Saint Louis, Missouri
This trial is testing whether adding Toradol, an anti-inflammatory drug, to the usual opioid painkillers can better manage pain after surgery in patients who have had a specific type of bone surgery. These patients are chosen because they don't need the body's natural inflammation process for healing. Toradol works by reducing inflammation, while opioids change how the brain perceives pain. Toradol, also known as ketorolac, is a nonsteroidal anti-inflammatory drug (NSAID) that has been studied for its opioid-sparing effects in postoperative pain management.
Extended Release Buprenorphine for Opioid Use Disorder
Recruiting1 awardPhase 2 & 3
New Haven, Connecticut
This trial is testing whether a 28-day formulation of extended-release buprenorphine is more effective than usual treatment for patients with a moderate or severe opioid use disorder who are seen by an addiction consultation service and agree to start a medication for OUD.
Trials With No Placebo
SIRI Checklist + Peer Coaching for HIV Prevention in Opioid Users
Recruiting1 award
Birmingham, Alabama
This trial will develop and test a checklist to increase evidence-based treatment for rural people who use drugs, including long-acting injectable agents. The hypothesis is that hospital-based care models can successfully engage rural people in effective addiction treatment and infection prevention, which is foundational to Ending the HIV epidemic in rural states.
Behavioural Intervention
Smartphone Apps for Opioid Use Disorder
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial would use apps to help prevent relapse among patients receiving treatment for opioid use disorder. The apps would track the person's location and offer targeted, personalized intervention when they enter an area at high risk for relapse.
Learning Health System Intervention for Substance Use Disorders
Recruiting1 award4 criteria
Indianapolis, Indiana
This trial seeks to address the national addiction crisis at its epicenter by creating alliances between the juvenile justice system and community mental health centers to disseminate addiction prevention and treatment.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.