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Trials With No Placebo
Corticosteroid
Reduced-Dose Steroids for Nephrotic Syndrome
Recruiting2 awardsPhase 3
Toronto, Ontario
This trial is a small study done before a larger study to see if using a lower dose of oral steroids is safe and effective in treating a type of kidney disease in children called steroid-sensitive nephrotic
Angiotensin Receptor Blocker and Endothelin Receptor Antagonist
Sparsentan for Proteinuric Kidney Disease
Recruiting1 awardPhase 2
Miami, Florida
This trial is testing sparsentan, a daily oral medication, in children with specific kidney diseases that cause high protein levels in urine. The goal is to see if it is safe and effective. Sparsentan helps by reducing protein leakage into the urine, which can protect the kidneys.
Behavioral Intervention
Mobile App for Nephrotic Syndrome Management
Recruiting1 award4 criteria
Atlanta, Georgia
This trial tests UrApp, a mobile app that helps families manage nephrotic syndrome in children by tracking urine tests and medication. It targets caregivers of children who struggle with disease management. The app uses the phone's camera to read urine tests, reminds caregivers to check urine, tracks results, and alerts doctors if needed.
Monoclonal Antibodies
Rituximab + Cyclosporine for Glomerulonephritis
Recruiting1 awardPhase 2
Bethesda, Maryland
This trial is testing the safety and effectiveness of combining two drugs to treat membranous nephropathy, a kidney disease associated with damage to the walls of the glomeruli. The first drug, rituximab, is an immunosuppressant that attempts to reduce the activity of the immune system. The second drug, cyclosporine, is a blood pressure lowering medication. The trial will last up to 2 years, and participants will have frequent blood and urine tests.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.