Bruton's Tyrosine Kinase (BTK) Inhibitor
Fenebrutinib for Relapsing Multiple Sclerosis
Recruiting1 awardPhase 3
Phoenix, Arizona
This trial will test whether fenebrutinib can help treat relapsing MS by reducing disability progression and relapse rate, compared to teriflunomide. If the results are positive, participants will have the option to continue taking fenebrutinib in an extension phase.
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Trials for MS Patients
Device
Cionic Neural Sleeve for Multiple Sclerosis
Recruiting1 award
Cleveland, Ohio
This trial tests the Cionic Neural Sleeve, a device that helps people with MS walk better by sending small electrical signals to their leg muscles. It targets individuals with MS who have trouble walking. The study will measure how well the device improves walking ability and quality of life.
Antihistamine
Clemastine Fumarate for Multiple Sclerosis
Recruiting2 awardsPhase 1 & 2
San Francisco, California
This trial tests Clemastine Fumarate to see if it can repair myelin in patients with relapsing-remitting multiple sclerosis who have chronic brain lesions. The medication helps immature brain cells develop into myelin-producing cells, potentially fixing the damage caused by MS.
Combination Therapies for Multiple Sclerosis
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial tests four different drugs, alone or in combination, on adults with progressive multiple sclerosis who are not responding well to current treatments. The goal is to see if these drugs can reduce harmful inflammation and immune activity in the brain and spinal fluid.
Phase 3 Trials
Immunomodulator
Dimethyl Fumarate for Multiple Sclerosis
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is testing the safety and effectiveness of BG00012 in children with RRMS, compared to another disease-modifying treatment. The long-term safety of BG00012 will also be assessed in children who completed Week 96 in Part 1 of the study.
Stem Cell Transplant
Stem Cell Transplant vs Best Available Therapy for Multiple Sclerosis
Recruiting2 awardsPhase 3
Palo Alto, California
This trial is testing whether AHSCT is better than BAT for treating people with MS who have not responded to other treatments. 156 people will be randomly assigned to either AHSCT or BAT, and followed for 72 months.
Trials With No Placebo
Device
Cionic Neural Sleeve for Multiple Sclerosis
Recruiting1 award
Cleveland, Ohio
This trial tests the Cionic Neural Sleeve, a device that helps people with MS walk better by sending small electrical signals to their leg muscles. It targets individuals with MS who have trouble walking. The study will measure how well the device improves walking ability and quality of life.
Combination Therapies for Multiple Sclerosis
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial tests four different drugs, alone or in combination, on adults with progressive multiple sclerosis who are not responding well to current treatments. The goal is to see if these drugs can reduce harmful inflammation and immune activity in the brain and spinal fluid.
Immunomodulator
Dimethyl Fumarate for Multiple Sclerosis
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is testing the safety and effectiveness of BG00012 in children with RRMS, compared to another disease-modifying treatment. The long-term safety of BG00012 will also be assessed in children who completed Week 96 in Part 1 of the study.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.