Popular Trials
Smartphone App Detection for Retinoblastoma
Recruiting1 award
Memphis, Tennessee
This trial is testing a smartphone app called CRADLE to help detect leukocoria in children. The app takes pictures of the eyes and looks for signs of this condition. It aims to improve early detection in kids who have or might have serious eye diseases.
Alkylating agents
Combination Chemotherapy + Cyclosporine and Focal Therapy for Retinoblastoma
Recruiting1 awardPhase 2
Vancouver, British Columbia
This trial is studying a combination of chemotherapy drugs with or without cyclosporine followed by cryotherapy (freezing) and/or laser therapy in treating patients with newly diagnosed retinoblastoma in both eyes.
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Trials With No Placebo
Alkylating agents
Intraocular Chemotherapy for Retinoblastoma
Recruiting1 awardPhase 2
Cleveland, Ohio
This trial tests the safety of adding a drug (melphalan) to standard chemotherapy to treat retinoblastoma (a type of cancer of the eye). It may help treat harder-to-treat cases and improve the ability to treat vitreous seeds.
CAR T-cell Therapy
CAR T Cell Therapy for Pediatric Cancer
Recruiting1 awardPhase 1
Seattle, Washington
This trial tests a new treatment for children and young adults with hard-to-treat solid tumors. It uses the patient's own immune cells, modified to better attack cancer cells. The study aims to see if this approach is safe and effective. This type of therapy has shown remarkable results in young patients with certain types of blood cancers.
Alkylating agents
Intra-arterial Chemotherapy for Retinoblastoma
Recruiting1 awardPhase 1
Saint Louis, Missouri
This trial is testing a new way to give chemotherapy to children with retinoblastoma, a cancer of the eye. Up to 3 doses of melphalan will be given through a small tube in the artery. Doctors will check if it is safe and effective.
Topoisomerase I inhibitor
Topotecan Episcleral Plaque for Retinoblastoma
Recruiting1 awardPhase 1
Toronto, Ontario
This trial is testing a new way to treat eye cancer in children using a small device that slowly releases a cancer drug directly onto the eye. It targets kids whose cancer didn't respond to other treatments. The goal is to see if this method is safe and works well without causing too many side effects.
CAR T-cell Therapy
CAR T Cell Therapy for Pediatric Solid Cancers
Recruiting1 awardPhase 1
Seattle, Washington
This trial is testing genetically-modified T cells to treat solid tumors in children and young adults. The goal is to evaluate safety and feasibility, and to determine if the cells can kill tumors.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.