Amino Acid
Levocarnitine for Dry Eye in Sjogren's Syndrome
Recruiting0 awardsPhase 2
Nashville, Tennessee
This trial tests levocarnitine, a supplement that helps transport carnitine into cells, in adults with Sjogren's syndrome who have dry eyes. Sjogren's syndrome causes dryness in the eyes and mouth. Levocarnitine may help by increasing carnitine levels in tears, potentially reducing eye dryness and improving comfort. Levocarnitine is a molecule required in mammalian energy metabolism, facilitating the transport of long-chain fatty acids across the mitochondrial membrane for energy production.
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Trials for SS Patients
Dazodalibep for Sjögren's Syndrome
Recruiting1 awardPhase 3
Beverly Hills, California
This trial is testing dazodalibep, a medication, to see if it can help people with moderate-to-severe Sjögren's Syndrome. The goal is to reduce their symptoms and improve their quality of life. Researchers will also check if the medication is safe and well-tolerated by patients.
Monoclonal Antibodies
Ianalumab for Sjogren's Syndrome
Recruiting1 awardPhase 3
Oklahoma City, Oklahoma
This trial is to measure long-term safety of ianalumab in participants with Sjogrens syndrome for up to 5 years; ianalumab will be given monthly or every 3 months (w/placebo in between). 600 participants will be enrolled. Some may self-inject at home.
Behavioural Intervention
Supportive Care for Arthritis
Recruiting1 award
Boston, Massachusetts
This trial tests whether providing tailored lists of resources and/or a specialized nurse navigator to patients with inflammatory arthritis and SDoH-related needs can reduce missed appointments and improve health outcomes.
Trials for Sjögren's Syndrome Patients
Monoclonal Antibodies
Ianalumab for Sjogren's Syndrome
Recruiting1 awardPhase 3
Oklahoma City, Oklahoma
This trial is to measure long-term safety of ianalumab in participants with Sjogrens syndrome for up to 5 years; ianalumab will be given monthly or every 3 months (w/placebo in between). 600 participants will be enrolled. Some may self-inject at home.
Phase 3 Trials
Dazodalibep for Sjögren's Syndrome
Recruiting1 awardPhase 3
Beverly Hills, California
This trial is testing dazodalibep, a medication, to see if it can help people with moderate-to-severe Sjögren's Syndrome. The goal is to reduce their symptoms and improve their quality of life. Researchers will also check if the medication is safe and well-tolerated by patients.
Monoclonal Antibodies
Ianalumab for Sjogren's Syndrome
Recruiting1 awardPhase 3
Oklahoma City, Oklahoma
This trial is to measure long-term safety of ianalumab in participants with Sjogrens syndrome for up to 5 years; ianalumab will be given monthly or every 3 months (w/placebo in between). 600 participants will be enrolled. Some may self-inject at home.
Trials With No Placebo
Behavioural Intervention
Supportive Care for Arthritis
Recruiting1 award
Boston, Massachusetts
This trial tests whether providing tailored lists of resources and/or a specialized nurse navigator to patients with inflammatory arthritis and SDoH-related needs can reduce missed appointments and improve health outcomes.
Aldehyde trapping agent
ADX-629 for Sjogren-Larsson Syndrome
Recruiting1 awardPhase 1 & 2
Omaha, Nebraska
This trial tests if ADX-629, a medicine taken by mouth, is safe and effective for people with Sjögren-Larsson syndrome (SLS). SLS is a rare genetic disorder that causes harmful fats to build up in the body. ADX-629 helps remove these harmful fats, which may reduce symptoms in the skin, brain, and eyes.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.