Glioblastoma Clinical Trials in Chicago, IL

View the best 10 glioblastoma medical studies in Chicago, Illinois. Access promising new therapies by applying to a Chicago-based Glioblastoma clinical trial.

Trials in Chicago, Illinois

Here are the top 10 medical studies for glioblastoma in Chicago, Illinois

Michael Bask Gill, B Sc

Last Reviewed: December 12th, 2024

SurVaxM

Cancer Vaccine

Recruiting1 awardPhase 1

This trial tests the SurVaxM vaccine, which helps the immune system target and destroy cancer cells, in children and young adults with certain difficult-to-treat brain cancers. The vaccine works by teaching the immune system to recognize a protein found in cancer cells. Additional substances are used to make the immune response stronger.

Optune®

Device

Recruiting1 award12 criteria

This trial is testing a new treatment for brain cancer that combines Optune with radiation and chemotherapy. The goal is to see if this new combination is more effective and has fewer side effects than current treatments.

INCB7839

Monoclonal Antibodies

Recruiting1 awardPhase 1

This trial tests INCB7839, a drug that blocks proteins helping cancer cells grow, on children with tough-to-treat brain tumors that have returned or grown after initial treatment. The drug works by stopping a protein needed for tumor growth from being released.

Berubicin +1 More

Anthracenedione

Recruiting1 awardPhase 2

This trial will compare the effect of two cancer drugs, berubicin and lomustine, on overall survival in patients with glioblastoma multiforme (GBM) who have failed standard first line therapy. A futility analysis will be performed after approximately 30-50% of planned patients have completed the primary endpoint at 6 months.

IGV-001 +2 More

Cell Immunotherapy

Recruiting0 awardsPhase 2

This trial will compare a new treatment for glioblastoma to placebo to see if it extends survival.

Intraoperative radiotherapy

Recruiting2 awardsPhase 3

This trial is testing if adding intraoperative radiotherapy (IORT) to standard radiochemotherapy can improve the median progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM).

Nivolumab +1 More

Monoclonal Antibodies

Recruiting1 awardPhase 2

"This trial is comparing the safety and effectiveness of two new drugs, relatlimab and nivolumab, with a standard chemotherapy drug called lomustine for treating patients with recurrent glioblast

Triamcinolone Acetonide

Recruiting1 awardPhase 2

This trial will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects for people being treated with Tumor Treating Fields for malignant glioma.

ST101

Virus Therapy

Recruiting1 awardPhase 1 & 2

This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.

Lomustine +2 More

Alkylating agents

Recruiting2 awardsPhase 3

This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.

Popular Filters

Trials With No Placebo

Cancer Vaccine

SurVaxM Vaccine for Brain Cancer

Recruiting1 awardPhase 1

Chicago, Illinois

This trial tests the SurVaxM vaccine, which helps the immune system target and destroy cancer cells, in children and young adults with certain difficult-to-treat brain cancers. The vaccine works by teaching the immune system to recognize a protein found in cancer cells. Additional substances are used to make the immune response stronger.

Anthracenedione

Berubicin for Glioblastoma

Recruiting1 awardPhase 2

Chicago, Illinois

This trial will compare the effect of two cancer drugs, berubicin and lomustine, on overall survival in patients with glioblastoma multiforme (GBM) who have failed standard first line therapy. A futility analysis will be performed after approximately 30-50% of planned patients have completed the primary endpoint at 6 months.

Radiation

Reduced-Dose Radiotherapy + Temozolomide for Glioblastoma

Recruiting2 awardsPhase 2

Milwaukee, Wisconsin

This trial is testing whether a lower dose of radiation therapy is just as effective as the standard dose in treating glioblastoma.

Monoclonal Antibodies

Tocilizumab + Atezolizumab + Radiation Therapy for Glioblastoma

Recruiting1 awardPhase 2

Chicago, Illinois

This trial tests a combination of tocilizumab, atezolizumab, and precise radiation therapy in patients with recurrent glioblastoma. Tocilizumab reduces inflammation, atezolizumab boosts the immune system, and the radiation targets the tumor. The goal is to make the tumor more responsive to treatment and improve patient outcomes.

Alkylating agents

Ultrasound-assisted Chemotherapy for Glioblastoma

Recruiting3 awardsPhase 1 & 2

Chicago, Illinois

This trial will test a new way of giving the chemotherapy drug paclitaxel to people with glioblastoma that has come back after surgery. In this trial, they will give the drug through a device that uses ultrasound to open the blood brain barrier for a short time so that the drug can get into the brain.

Virus Therapy

ST101 for Advanced Cancer

Recruiting1 awardPhase 1 & 2

Warrenville, Illinois

This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.

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Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.