Behavioural Intervention
Parent-Mediated Intervention for Autism
Recruiting1 award2 criteria
Lawrence, Kansas
"This trial aims to see if using a technique called the 'mutual gaze procedure' in a specific therapy program can help improve social communication, language, and everyday skills in young Hispanic children with autism who
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Phase 3 Trials
RNAi Therapeutics
Vutrisiran for Amyloid Cardiomyopathy
Recruiting2 awardsPhase 3
Kansas City, Kansas
This trial aims to gather information on the safety and effectiveness of using vutrisiran in patients with a certain type of heart disease called ATTR amyloidosis. The study will look at patients who either
Tranexamic acid for Blood Loss
Recruiting1 awardPhase 3
Kansas City, Kansas
Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that has been well studied and routinely used for hip and knee arthroplasty. In hip and knee arthroplasty, the use of tranexamic acid decreases blood loss and the need for transfusion without increasing the risk of thromboembolic events. Due to the increased use of reverse total shoulder arthroplasty in the treatment of shoulder pathology, there has been interest in making the procedure safer for patients. TXA is a promising drug which could be useful to surgeons as they seek to achieve this goal, however, it has not been extensively studied in this setting. The purpose of this prospective randomized, controlled study is to determine the effectiveness and safety of using tranexamic acid to decrease blood loss in reverse total shoulder arthroplasty.
Trials With No Placebo
Patients with MR for Mitral Valve Prolapse
Recruiting1 award2 criteria
Kansas City, Missouri
This is a qualitative and quantitative study that seeks to obtain information from patients with degenerative mitral valve prolapse and providers regarding factors important in deciding between surgical mitral valve repair (MVR) and transcatheter edge-to-edge repair (TEER). Findings from this study will provide data that can be used to develop decision aids that can assist patients in decision making between these two therapies and assist providers in integrating shared decision making the within the multidisciplinary heart valve team.
Procedure
Incision Techniques for Umbilical Hernia
Recruiting1 award2 criteria
Kansas City, Missouri
This trial will involve patients coming in for umbilical hernia repair. They will be randomly assigned to receive different types of repair. Data will be collected on the day of surgery, and patients will
Participants With Signs and Symptoms of Acute Coronary Syndromes for Heart Attack
Recruiting1 award10 criteria
Kansas City, Kansas
This prospective, non-interventional, single arm, longitudinal cohort multicenter study will recruit approximately 5600 consecutive all-comers, consisting of patients with signs and symptoms of acute coronary syndromes (ACS) who present in the emergency department (ED). The main objective of the study is to determine the clinical performance of Elecsys Troponin T hs Gen 6 versus the centrally adjudicated clinical diagnosis at various time points after ED presentation using the previously determined clinical cut-off of a universal 99th percentile upper reference limit.
Trials Offering Remuneration
Period 1: Nemtabrutinib for Healthy Subjects
Recruiting1 awardPhase 1
Overland Park, Kansas
The goal of the study is to learn what happens to levels of nemtabrutinib (MK-1026) in a healthy person's body over time. Researchers will compare what happens to nemtabrutinib in the body when it is given with or without another medicine called efavirenz.
MK-6552 + Diltiazem for Healthy Subjects
Recruiting1 awardPhase 1
Lenexa, Kansas
The main goal of this study is to learn what happens to MK-6552 in a person's body over time (a pharmacokinetic or PK study). Researchers want to know what happens to MK-6552 in healthy adults when a single dose of MK-6552 is given with multiple doses of diltiazem. The researchers believe that multiple doses of diltiazem will not affect the highest amount of MK-6552 in the blood.
Enlicitide Chloride for Coronary Artery Disease
Recruiting0 awardsPhase 1
Overland Park, Kansas
The goal of this study is to learn what happens to different doses of enlicitide chloride over time in the body of healthy participants and participants taking statins, a group of medicines used to reduce the levels of high cholesterol in the bloodstream. The researchers want to learn about the safety of enlicitide chloride when administered at high doses.
Digoxin for Healthy Subjects
Recruiting1 awardPhase 1
Lenexa, Kansas
The goal of the study is to learn what happens to levels of digoxin in a healthy person's body over time. Researchers will compare what happens to digoxin in the body when it is given with and without another medicine called nemtabrutinib. Researchers are testing if digoxin levels in the body are different when digoxin is given with or without nemtabrutinib.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.