Popular Trials
Radiofrequency Ablation
Radiofrequency Ablation for Lower Back Pain
This trial tests two methods of using heat to destroy nerve tissue in patients with lower back pain from the sacroiliac joint. The goal is to see which method is better at reducing pain by stopping pain signals from reaching the brain.
Behavioural Intervention
ED Physical Therapy for Lower Back Pain
This trial will evaluate an innovative model of an emergency department "embedded" physical therapist to treat patients with chronic low back pain, with a focus on improving patient functioning and reducing opioid use.
Allograft
VIA Disc NP for Degenerative Disc Disease
This trial tests VIA Disc NP, a tissue injection for repairing damaged spine discs, in adults whose condition hasn't improved with usual treatments. The injection aims to support and heal the damaged discs, potentially reducing pain and improving function.
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Trials for LBP Patients
Behavioural Intervention
DuoTherm vs TENS for Lower Back Pain
This trial compares a belt that provides vibration, heat, cold, and pressure (DuoTherm) to a device that uses electrical stimulation in patients with acute low back pain. DuoTherm helps by relaxing muscles and reducing inflammation, while the other device blocks pain signals from reaching the brain. The electrical stimulation device has been used for pain relief in various conditions, including chronic low back pain, but its effectiveness needs more research.
Behavioral Intervention
Integrated vs. Coordinated Pain Management for Back Pain
This trial is testing whether an Integrated Care Pathway or a Coordinated Care Pathway is more effective in reducing pain and improving function for people with low back pain.
Watchful Waiting Strategy for Lower Back Pain
This trial will test whether using actors to portray patients can help doctors learn how to better offer watchful waiting as a means of avoiding low-value spinal imaging for patients with acute low back pain.
Behavioral Intervention
Stepped Care Management for Lower Back Pain
This trial will study two possible treatments for chronic low back pain, physical therapy or Move 2 Health. If neither of these treatments work after six weeks, patients will then be randomized to receive either the addition of the other treatment or the MORE Mindfulness intervention.
Trials for Low Back Pain Patients
Behavioural Intervention
DuoTherm vs TENS for Lower Back Pain
This trial compares a belt that provides vibration, heat, cold, and pressure (DuoTherm) to a device that uses electrical stimulation in patients with acute low back pain. DuoTherm helps by relaxing muscles and reducing inflammation, while the other device blocks pain signals from reaching the brain. The electrical stimulation device has been used for pain relief in various conditions, including chronic low back pain, but its effectiveness needs more research.
Behavioral Intervention
Integrated vs. Coordinated Pain Management for Back Pain
This trial is testing whether an Integrated Care Pathway or a Coordinated Care Pathway is more effective in reducing pain and improving function for people with low back pain.
Watchful Waiting Strategy for Lower Back Pain
This trial will test whether using actors to portray patients can help doctors learn how to better offer watchful waiting as a means of avoiding low-value spinal imaging for patients with acute low back pain.
Behavioral Intervention
Stepped Care Management for Lower Back Pain
This trial will study two possible treatments for chronic low back pain, physical therapy or Move 2 Health. If neither of these treatments work after six weeks, patients will then be randomized to receive either the addition of the other treatment or the MORE Mindfulness intervention.
Trials With No Placebo
Behavioural Intervention
DuoTherm vs TENS for Lower Back Pain
This trial compares a belt that provides vibration, heat, cold, and pressure (DuoTherm) to a device that uses electrical stimulation in patients with acute low back pain. DuoTherm helps by relaxing muscles and reducing inflammation, while the other device blocks pain signals from reaching the brain. The electrical stimulation device has been used for pain relief in various conditions, including chronic low back pain, but its effectiveness needs more research.
Behavioral Intervention
Integrated vs. Coordinated Pain Management for Back Pain
This trial is testing whether an Integrated Care Pathway or a Coordinated Care Pathway is more effective in reducing pain and improving function for people with low back pain.
Behavioral Intervention
Stepped Care Management for Lower Back Pain
This trial will study two possible treatments for chronic low back pain, physical therapy or Move 2 Health. If neither of these treatments work after six weeks, patients will then be randomized to receive either the addition of the other treatment or the MORE Mindfulness intervention.
View More Related Trials
Frequently Asked Questions
Introduction to lower back pain
What are the top hospitals conducting lower back pain research?
When it comes to finding relief for lower back pain, several hospitals are leading the way in clinical trials. Chicago's Northwestern Memorial Hospital is currently conducting two active trials focused on this common and often debilitating condition. While their all-time record may be modest with only two completed trials, they have made significant progress since recording their first lower back pain trial in 2021.
In Texas, both Brooke Army Medical Center and Wilford Hall Ambulatory Surgical Center in San Antonio are actively involved in addressing lower back pain through ongoing studies. Brooke Army Medical Center has conducted a total of six trials since initiating their first one in 2015, while Wilford Hall Ambulatory Surgical Center has completed two trials thus far since starting their journey into understanding lower back pain just a bit later, in 2019.
Moving across states to Tacoma, Madigan Army Medical Center maintains an equal dedication to combating lower back discomfort with its involvement in two current clinical trials. They have also made notable contributions over time by conducting three previous studies since embarking on this path of research as early as 2012.
Meanwhile, the University of Florida's commitment shines through with not only two ongoing clinical trials but an impressive eleven cumulative studies dedicated to exploring solutions for lower back pain. Their earliest recorded trial dates all the way back to 2004 when they recognized the importance of delving into this pervasive issue that affects so many individuals.
These top hospitals' involvement demonstrates a collective effort towards understanding and alleviating the burden of lower back pain experienced by countless people worldwide. By investing resources into innovative research and clinical investigations, these institutions offer hope for improved treatment options and ultimately aim to enhance quality of life for those struggling with this prevalent condition.
Which are the best cities for lower back pain clinical trials?
When it comes to lower back pain clinical trials, several cities emerge as key players in advancing research and treatment options. Salt Lake City, Utah leads the way with 5 active trials focusing on Telehealth Physical Therapy, Mindfulness techniques, and Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA), among others. San Diego, California closely follows with 4 ongoing studies investigating interventions like GOALS Intervention and Protein supplements. Additionally, San Antonio, Texas contributes to the field with 4 active trials exploring Standard Care (SC) and Physical Therapy approaches. These cities provide valuable opportunities for individuals suffering from lower back pain to participate in cutting-edge clinical trials that may pave the way for improved management strategies and enhanced quality of life.
Which are the top treatments for lower back pain being explored in clinical trials?
Exciting developments are underway in the realm of lower back pain treatments, with several options showing promise in clinical trials. One such contender is VIA Disc NP, currently being explored in two active trials specifically targeting lower back pain. Additionally, ED Physical Therapy has also caught the attention of researchers and is involved in two ongoing trials dedicated to addressing this prevalent issue. Another newcomer making waves is ABCp, which has shown potential in one active trial for alleviating lower back pain. As these treatments continue to undergo rigorous testing and evaluation, hope shines bright for those seeking relief from this debilitating condition.
What are the most recent clinical trials for lower back pain?
Recent clinical trials have brought promising advancements in the field of lower back pain research. One notable study investigated the effectiveness of Dextrose 50% Intravenous Solution, which has shown potential as a treatment option for this condition. Another trial focused on combining ibuprofen, dexamethasone, and educational interventions to address lower back pain. Additionally, researchers explored Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA) as a potential therapy for this type of pain. Furthermore, telehealth physical therapy emerged as an innovative approach to managing lower back pain from the comfort of one's home. These ongoing studies highlight the commitment to finding effective solutions that can significantly improve the lives of individuals suffering from lower back pain.
What lower back pain clinical trials were recently completed?
Recently completed clinical trials have made significant strides in advancing the understanding and treatment of lower back pain. Notably, Scilex Pharmaceuticals, Inc.'s trial investigating SP-103 reached completion in April 2022. The diligent efforts of Eli Lilly and Company were also evident through their successful completion of several trials: LY3526318 in October 2021, LY3556050 in May 2021, and LY3016859 in August 2020. These achievements contribute to the growing body of knowledge aimed at addressing this prevalent and burdensome condition.