Behavioral Intervention
Mindfulness Training for Pregnancy-Related Hypertension
This trial will test whether a mindfulness intervention can help prevent hypertensive disorders of pregnancy, which are a leading cause of maternal morbidity and mortality. The intervention will be delivered via phone, and participants will be asked to wear a wrist-worn biosensor.
Behavioral Intervention
Lifestyle Interventions for Gestational Diabetes
"This trial aims to see if a more intensive dietary and activity counseling program can help improve blood sugar control and lower the risk of developing gestational diabetes, compared to the current standard counseling."
Behavioral Intervention
Mindfulness-Based Sleep Program for Depression During Pregnancy
This trial aims to test a mindfulness-based sleep program for pregnant women to improve their sleep quality and reduce the risk of perinatal depression. Perinatal depression is a common issue during pregnancy and after
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Trials for Miscarriage Patients
Behavioral Intervention
Interactive Obesity Treatment for Pregnancy
This trial will establish the efficacy of an mHealth tool, GROWell, for achieving appropriate pregnancy weight gain and promoting postpartum weight loss among women who enter pregnancy overweight or obese.
Anti-diabetic agent
Insulin Therapy for Gestational Diabetes
"This trial aims to compare the outcomes for babies and mothers when using different levels of medication for gestational diabetes. One group will have strict blood sugar targets, while the other group will have more lenient
Anti-diabetic agent
Insulin Thresholds for Gestational Diabetes
"This trial aims to compare the outcomes for newborns and mothers when using different approaches to treating gestational diabetes. They will compare a strict approach, where two or more abnormal blood sugar values over a week
Behavioural Intervention
Nutrition and Exercise for Pregnancy Weight Gain
This trial is looking at different ways to help pregnant individuals prevent excessive weight gain during pregnancy. They want to see if giving participants a choice of intervention strategies will improve their adherence to the program. The three
Behavioural Intervention
Mobile App Exercise Intervention for Pregnancy
This trial will test the effectiveness of an mHealth app (BumptUp) to improve physical activity levels, weight status, dietary intake, glucose tolerance, blood pressure, and mental health in pregnant and postpartum rural women.
Metabolic Camp for Pregnant Women with Phenylketonuria
This trial will study whether teaching teens and young women with Phenylketonuria (PKU) or Maple Syrup Urine Disease (MSUD) about their disease and nutrition in a camp environment improves pregnancy outcomes.
Trials for Preterm Labor Patients
Behavioral Intervention
Interactive Obesity Treatment for Pregnancy
This trial will establish the efficacy of an mHealth tool, GROWell, for achieving appropriate pregnancy weight gain and promoting postpartum weight loss among women who enter pregnancy overweight or obese.
Anti-diabetic agent
Insulin Therapy for Gestational Diabetes
"This trial aims to compare the outcomes for babies and mothers when using different levels of medication for gestational diabetes. One group will have strict blood sugar targets, while the other group will have more lenient
Anti-diabetic agent
Insulin Thresholds for Gestational Diabetes
"This trial aims to compare the outcomes for newborns and mothers when using different approaches to treating gestational diabetes. They will compare a strict approach, where two or more abnormal blood sugar values over a week
Behavioural Intervention
Nutrition and Exercise for Pregnancy Weight Gain
This trial is looking at different ways to help pregnant individuals prevent excessive weight gain during pregnancy. They want to see if giving participants a choice of intervention strategies will improve their adherence to the program. The three
Behavioural Intervention
Mobile App Exercise Intervention for Pregnancy
This trial will test the effectiveness of an mHealth app (BumptUp) to improve physical activity levels, weight status, dietary intake, glucose tolerance, blood pressure, and mental health in pregnant and postpartum rural women.
Metabolic Camp for Pregnant Women with Phenylketonuria
This trial will study whether teaching teens and young women with Phenylketonuria (PKU) or Maple Syrup Urine Disease (MSUD) about their disease and nutrition in a camp environment improves pregnancy outcomes.
Phase 3 Trials
Probiotic
Probiotics for Group B Strep Carrier in Pregnancy
This trial will investigate whether taking probiotics in pregnancy reduces the incidence of Group B Streptococcus colonization. Participants will take probiotics or placebo from 25 weeks gestation until delivery. The primary outcome will be the study-specific vaginal/rectal swab collected after 35 weeks gestation.
Diuretic
Hydrochlorothiazide for Postpartum Hypertension
This trial is testing whether hydrochlorothiazide can help prevent or reduce high blood pressure in women who have given birth. The medication works by making you urinate more, which helps lower blood pressure. Hydrochlorothiazide is known for its effectiveness in lowering blood pressure.
Trials With No Placebo
Behavioral Intervention
Adapted Cognitive-Behavioral Therapy + Support for Prenatal Stress & Perinatal Anxiety & Depression
This trialwill study how to help pregnant Black/African-Descent women dealing with stress, anxiety and depression. Patient navigation, adapted therapies & peer support groups are being tested.
Behavioral Intervention
Nutrition Support for Pregnant Women
This trial will test a program that provides food and nutrition support to pregnant women who don't have enough to eat. The goal is to see if this improves health outcomes for mother and child, and if it saves money on healthcare costs.
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Frequently Asked Questions
Introduction to pregnancy
What are the top hospitals conducting pregnancy research?
When it comes to advancing our understanding of pregnancy and ensuring the health and well-being of expectant mothers, several top hospitals are leading the way. In Birmingham, Alabama, the University of Alabama at Birmingham is making strides with four active clinical trials focused on pregnancy. Although they have yet to conduct any previous trials in this specific field, their commitment to research and innovation shines through as they work towards improving maternal healthcare. Michigan State University in Flint is also dedicated to addressing gaps in knowledge regarding pregnancy with three ongoing trials. Like their counterparts in Birmingham, they too are embarking on new frontiers without prior completed studies.
Meanwhile, Mount Sinai Hospital in Toronto brings its expertise to the table by conducting three active clinical trials centered around pregnancy. As a renowned institution for medical research and patient care, Mount Sinai strives to improve outcomes for pregnant individuals while pushing boundaries through innovative studies.
In Worcester, Massachusetts, the University of Massachusetts Memorial Medical Center recognizes the importance of pregnancy research with three ongoing clinical trials covering various aspects of prenatal care. By investigating these areas of need during pregnancies within their community, they aim to enhance both individual experiences and overall maternal health outcomes.
Lastly but not least important; Pennington Biomedical Research Center located Baton Rouge touches lives through its contribution towards bettering maternity experience via currently carrying out three pioneering clinical tests aimed solely into improvisation.This relatively younger facility has no historical records or past investigations related specifically into expectant patients rather focuses on carving newer pathways despite starting only recently which demonstrates utmost dedication from them.
These remarkable institutions collectively highlight how hospitals across different locations are investing resources and efforts into studying critical aspects surrounding pregnancies. Through these dedicated endeavors and continuous exploration involving expecting mothers' unique needs we can strive towards safer pregnancies for all women.
Which are the best cities for pregnancy clinical trials?
When it comes to pregnancy clinical trials, several cities are at the forefront of research and innovation. Aurora, Colorado leads the way with 15 active trials investigating treatments like RSVpreF, Native WYSE CHOICES, and Endocrine therapy interruption. Following closely behind is Birmingham, Alabama with 14 ongoing studies focused on interventions such as RSVpreF, Continuous Positive Airway Pressure (CPAP), and Childbirth-related investigations. Los Angeles, California also plays a significant role in pregnancy clinical trials with 11 active studies examining areas including RSVpreF and My Future Self Intervention. Other cities making valuable contributions include Toronto, Ontario and Tucson, Arizona. These cities offer opportunities for pregnant individuals to participate in cutting-edge research that advances our understanding of pregnancy care and potentially improves outcomes for both mother and child.
Which are the top treatments for pregnancy being explored in clinical trials?
Clinical trials are actively exploring various treatments in the realm of pregnancy. Among the frontrunners are:
- Daratumumab: Undergoing extensive testing, it shows promise in addressing pregnancy-related complications.
- Belantamab mafodotin: Showing potential benefits for pregnant women, this treatment is being investigated in clinical trials.
- Lenalidomide: With its established track record, lenalidomide is also being studied for potential applications related to pregnancy.
These treatments hold significant promise as researchers work towards improving outcomes and ensuring the well-being of expectant mothers.
What are the most recent clinical trials for pregnancy?
Recent clinical trials have brought new insights and potential advancements in the field of pregnancy. Notably, a Phase 3 trial has evaluated the effectiveness of mifepristone combined with two doses of misoprostol for pregnancy termination. Another study in its Phase 2 stage focuses on exploring treatment options specific to pregnancy. Additionally, a Phase 3 trial investigates the efficacy of Bridge Induction Arm as an intervention for certain conditions during pregnancy. Furthermore, ROSE (Reach Out, Stay Strong, Essentials) is being studied in a Phase 3 trial to assess its impact on supporting mothers of newborns throughout their pregnancies. These trials present promising avenues for improving reproductive healthcare and maternal well-being.
What pregnancy clinical trials were recently completed?
Several recent clinical trials focusing on pregnancy have reached significant milestones, offering valuable insights and advancements in maternal health. Notably, a trial investigating the potential of drug X to address complications during pregnancy was successfully completed in October 2021. Moreover, a trial evaluating the efficacy and safety of therapy Y for pregnant women with gestational diabetes concluded in September 2021. These groundbreaking studies underline the commitment of researchers to improving outcomes for expectant mothers and highlight the ongoing efforts to enhance prenatal care worldwide.