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Trials for PN Patients
Monoclonal Antibodies
Dupilumab for Prurigo Nodularis
This trial is a Phase 3 study that will look at how the body processes a drug and its safety. It will involve multiple medical centers and will be open-label. Participants will go through three periods
Janus Kinase (JAK) Inhibitor
Ruxolitinib Cream for Prurigo Nodularis
This trial tests the safety and tolerability of a cream for people with Prurigo Nodularis, a condition with itchy skin nodules. The cream works by blocking enzymes that cause inflammation and itching. It has been previously tested for its effects in conditions like atopic dermatitis.
Phase 3 Trials
Monoclonal Antibodies
Dupilumab for Prurigo Nodularis
This trial is a Phase 3 study that will look at how the body processes a drug and its safety. It will involve multiple medical centers and will be open-label. Participants will go through three periods
Janus Kinase (JAK) Inhibitor
Ruxolitinib Cream for Prurigo Nodularis
This trial tests the safety and tolerability of a cream for people with Prurigo Nodularis, a condition with itchy skin nodules. The cream works by blocking enzymes that cause inflammation and itching. It has been previously tested for its effects in conditions like atopic dermatitis.
Frequently Asked Questions
Introduction to prurigo nodularis
What are the top hospitals conducting prurigo nodularis research?
When it comes to pioneering clinical trials in the field of prurigo nodularis, several hospitals are at the forefront of research and offering hope to patients. In Arkansas, the Northwest Arkansas Clinical Trials Center has taken an active role in this area with their ongoing trial and a singular completed study dedicated to prurigo nodularis. This hospital made history by recording its first-ever trial for this condition in 2023. Similarly, Dermatology Research Associates in Los Angeles has also embarked on a groundbreaking journey with one active prurigo nodularis trial and one completed trial under its belt. They too entered into uncharted territory by initiating their first study on prurigo nodularis in 2023.
Heading over to Santa Monica's Clinical Science Institute Clinical Research Specialists Inc., they have joined the mission of advancing knowledge about prurigo nodularis through their own ongoing clinical trial as well as having accomplished one previous study. Their venture began just recently in 2023 when they recorded their initial breakthrough investigation tackling this condition head-on. Meanwhile, Cura Clinical Research located in Sherman Oaks is equally committed with an ongoing active prurigo nodularis trial along with successfully concluding another prior study; both endeavors were launched for the first time ever during 2023.
Last but not least, Pureskin Dermatology and Aesthetics based out of Orlando also joins these esteemed institutions by dedicating themselves to understanding and combating prurigo nodularis through an active clinical trial alongside a single previously conducted study—both marking significant milestones achieved just last year in 2023.
These hospitals exemplify dedication towards uncovering new treatments and improving outcomes for individuals living with the challenging condition that is prurigo nodularis. Through their efforts, progress is being made each day, offering hope for relief and enhanced quality of life for those affected worldwide
Which are the best cities for prurigo nodularis clinical trials?
When it comes to prurigo nodularis clinical trials, several cities have emerged as prominent hubs for research and advancements. Baltimore, Maryland; Dublin, Ohio; Austin, Texas; Phoenix, Arizona; and Fountain Valley, California are all at the forefront of ongoing studies for this condition. These cities collectively host three active trials each that investigate promising treatments such as Ruxolitinib 1.5% Cream, INCB054707, Nemolizumab, among others. Individuals seeking innovative approaches to managing prurigo nodularis can find opportunities to participate in cutting-edge clinical trials in these locations across the United States.
Which are the top treatments for prurigo nodularis being explored in clinical trials?
Exciting developments are underway in the field of prurigo nodularis treatment, with two standout contenders taking center stage in clinical trials. INCB054707 is being explored in one active trial dedicated to this condition. It made its debut on the scene in 2021 and shows promising potential as a therapeutic option. Another frontrunner is nemolizumab, which has caught the attention of researchers with one ongoing trial and three all-time prurigo nodularis studies since its introduction in 2020. These innovative treatments offer hope for patients suffering from this challenging skin disorder, paving the way for improved management and relief.
What are the most recent clinical trials for prurigo nodularis?
Exciting advancements in the field of prurigo nodularis research have emerged through recent clinical trials. Notably, a Phase 3 trial investigating the efficacy of Ruxolitinib 1.5% Cream has shown promising results for this challenging condition. With its potential to provide relief and improve patient outcomes, this cream represents an important development in prurigo nodularis treatment. Additionally, another Phase 2 study explored the effectiveness of INCB054707 in managing symptoms associated with prurigo nodularis, further expanding our understanding of potential therapeutic options. These groundbreaking trials offer hope for individuals affected by this distressing skin disorder and highlight significant progress towards finding effective treatments.
What prurigo nodularis clinical trials were recently completed?
In the realm of prurigo nodularis, several recent clinical trials have made significant strides towards advancing treatments for this challenging condition. Notably, Galderma R&D completed a trial in January 2022 examining the effectiveness of Nemolizumab. Likewise, Celldex Therapeutics concluded their study on CDX-0159 in November 2021, while Johns Hopkins University successfully wrapped up a trial investigating Abrocitinib in September 2021. These trials contribute to our growing understanding and offer hope for individuals afflicted by prurigo nodularis, highlighting the dedication of researchers and pharmaceutical companies alike in tackling this condition head-on.