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Procedure
Gonadal Tissue Cryopreservation for Fertility Preservation
This trial aims to investigate a method called gonadal tissue cryopreservation for preserving fertility in patients with certain disorders. These disorders can increase the risk of cancer and infertility. The study will assess how safe
C-type natriuretic peptide analog
Vosoritide for Turner Syndrome
This trial tests vosoritide, a medication that helps bone growth, in young girls with Turner syndrome who are short. It aims to see if vosoritide can help them grow taller, especially if they haven't responded well to other treatments.
Growth Hormone Medicine
Somapacitan for Growth Hormone Deficiency in Children
This trial is testing somapacitan, a new growth hormone medicine, in children who have low levels of growth hormone. These children include those born small for their age or with conditions like Turner syndrome, Noonan syndrome, or idiopathic short stature. Somapacitan is given as an injection to help them grow better. Somapacitan is a long-acting growth hormone derivative developed for periodic administration, already approved for use in adult GH deficiency in the USA and Japan.
Growth Hormone
Lonapegsomatropin vs Somatropin for Turner Syndrome
This trial is testing a new growth hormone treatment for young children with Turner syndrome to help them grow. The new treatment lasts longer in the body, so it doesn't need to be given as frequently. Growth hormone therapy has been used for many years to treat Turner syndrome, showing varied results in improving height.
Growth Hormone
Somapacitan vs Norditropin for Growth Disorders
This trial compares two growth hormone treatments for children with growth issues. Somapacitan is a new treatment, while Norditropin® is an existing treatment. The study aims to find out which treatment helps these children grow better. Somapacitan is a long-acting growth hormone derivative in development for treatment of GH deficiency.
Behavioural Intervention
PIXI for Neurogenetic Disorders
This trial tests a program called PIXI, which helps parents of infants with genetic disorders. The program educates parents about their baby's condition, coaches them on how to interact with their baby, and provides family support. The goal is to improve the baby's development and family well-being.
Frequently Asked Questions
Introduction to turner syndrome
What are the top hospitals conducting turner syndrome research?
When it comes to pioneering clinical trials in the realm of Turner syndrome, a rare genetic disorder affecting females, Novo Nordisk Investigational Sites are leading the way. Spread across four different locations - Sacramento, Centennial, Washington, and Idaho Falls - these facilities collectively boast an impressive total of 10 active Turner syndrome trials. Each site is currently engaged in two ongoing studies focused on this condition while having completed two previous trials as well. The year 2022 marked a significant milestone for these hospitals as they recorded their first-ever Turner syndrome trial, signaling a newfound dedication to understanding and improving the lives of those affected by this complex disorder.
Turner syndrome occurs when one sex chromosome (typically one X chromosome) is completely or partially missing in females. This genetic anomaly can lead to various health issues and typically results in short stature, delayed puberty, infertility, and heart-related complications among other potential challenges. By conducting clinical trials specific to Turner syndrome at multiple sites around the country under the banner of Novo Nordisk Investigational Sites' collective effort signifies their commitment towards combating this condition head-on.
While still relatively small-scale compared to more prevalent diseases being researched extensively today; such efforts highlight that organizations like Novo Nordisk continue striving for progress even in niche areas where research might be limited due to rarity but nonetheless immensely impactful when considering individuals personally impacted by them worldwide. These endeavors serve not only as beacons of hope for those with Turner syndrome but also underscore how medical advancements are made possible through innovative research conducted by dedicated professionals who aim to make tangible differences in patients' lives.
Which are the best cities for turner syndrome clinical trials?
When it comes to Turner syndrome clinical trials, several cities stand out for their active research initiatives. Washington, D.C., Saint Paul in Minnesota, Sacramento in California, Centennial in Colorado, and Idaho Falls are leading the way with ongoing studies. These trials focus on investigating treatments such as Somapacitan and Lonapegsomatropin at varying dosages to better understand their efficacy for individuals with Turner syndrome. With multiple trials happening across these cities, individuals with Turner syndrome have access to cutting-edge research that aims to improve treatment options and enhance quality of life.
Which are the top treatments for turner syndrome being explored in clinical trials?
Exciting advancements are underway in the field of Turner syndrome research, with a key focus on investigating potential treatments. Taking center stage is somapacitan, currently being explored in two active clinical trials dedicated to Turner syndrome. This innovative therapy made its debut in 2022 and shows promising potential for addressing the specific needs of individuals with this condition. As researchers delve deeper into these trials, they aim to unearth new avenues for improving the lives of those affected by Turner syndrome.
What are the most recent clinical trials for turner syndrome?
Exciting developments are occurring in the field of Turner syndrome research, with several recent clinical trials offering hope for improved treatments. Notably, lonapegsomatropin has shown promise as a potential therapy, administered at a dosage of 0.24 mg hGH/kg/week. This Phase 2 trial aims to assess its efficacy in individuals with Turner syndrome. Additionally, somapacitan is being investigated through two separate Phase 3 trials for the treatment of this condition. These studies focus on evaluating the safety and effectiveness of somapacitan in individuals with Turner syndrome, marking significant progress towards enhancing patient care and outcomes for those affected by this disorder.
What turner syndrome clinical trials were recently completed?
Recently completed clinical trials for Turner syndrome include a trial sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) that investigated the effects of growth hormone treatment in girls with Turner syndrome. Another study, sponsored by Opko Biologics, evaluated the efficacy and safety of an experimental medication for improving height outcomes in children with this condition. These trials contribute valuable insights into potential treatments for Turner syndrome and bring hope to individuals affected by this genetic disorder.