Dr. Aasef G. Shaikh, MD PhD
Claim this profileLouis Stokes VA Medical Center, Cleveland, OH
Studies Parkinson's Disease
Studies Psychosis
4 reported clinical trials
5 drugs studied
Area of expertise
1Parkinson's Disease
Stage III
Stage I
Stage II
2Psychosis
Affiliated Hospitals
Clinical Trials Aasef G. Shaikh, MD PhD is currently running
Pimavanserin vs. Quetiapine
for Psychosis in Parkinson's Disease
Patients with Parkinson's disease (PD) sometimes experience symptoms affecting their movement, such as slowness, tremor, stiffness, and balance or walking problems. Many patients also have other symptoms not related to movement, called non-motor symptoms, which may affect one's mood or emotions, memory or thinking, or cause one to see or hear things that aren't real (hallucinations) or believe things that aren't true (delusions). Hallucinations or delusions, together called psychosis, occur in up to 60% of PD patients at some point in time. Parkinson's disease psychosis can sometimes be associated with decreased quality of life, increased nursing home placement, increased rate of death, and greater caregiver burden. There are approximately 50,000 Veterans with Parkinson's disease receiving care in the VA, and up to 30,000 (60%) of them will experience psychosis at some point in time. Quetiapine is an antipsychotic drug approved by the Food and Drug Administration (FDA) that is the most commonly used medication to treat PD psychosis, but more studies are needed to determine if it works for this condition and is also well tolerated and safe. Pimavanserin is a newer antipsychotic drug approved by the Food and Drug Administration (FDA) specifically to treat PD psychosis, but more studies are needed to determine if it works and its safety. The purpose of this research is to gather additional information on the safety and effectiveness of both Quetiapine and Pimavanserin. By doing this study, the investigators hope to learn which of these medications is the most effective course of treatment for people with PD psychosis.
Recruiting3 awards Phase 46 criteria
Virtual Rehab Cycling
for Parkinson's Disease
This research will develop novel and accessible way to deliver effective and customized rehab to those suffering from common and devastating neurodegenerative condition called Parkinson's disease. The investigators will examine the efficacy of novel rehab technique that can be monitored and modified in real-time but over virtual interface using a remotely located device in a paradigm called dynamic cycling. This technology will benefit thousands of Veterans who need customized and cost-effective rehab but cannot travel to specialized facilities due to inevitable limitations such as pandemics or because of lack of resources, social support, frailty, or home-bound status.
Recruiting1 award N/A4 criteria
More about Aasef G. Shaikh, MD PhD
Clinical Trial Related2 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Aasef G. Shaikh, MD PhD has experience with
- Dynamic Cycling
- Forced Cycling
- Deep Brain Stimulation
- Pimavanserin
- Quetiapine
Breakdown of trials Aasef G. Shaikh, MD PhD has run
Parkinson's Disease
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Aasef G. Shaikh, MD PhD specialize in?
Aasef G. Shaikh, MD PhD focuses on Parkinson's Disease and Psychosis. In particular, much of their work with Parkinson's Disease has involved Stage III patients, or patients who are Stage I.
Is Aasef G. Shaikh, MD PhD currently recruiting for clinical trials?
Yes, Aasef G. Shaikh, MD PhD is currently recruiting for 2 clinical trials in Cleveland Ohio. If you're interested in participating, you should apply.
Are there any treatments that Aasef G. Shaikh, MD PhD has studied deeply?
Yes, Aasef G. Shaikh, MD PhD has studied treatments such as Dynamic cycling, Forced cycling, Deep Brain Stimulation.
What is the best way to schedule an appointment with Aasef G. Shaikh, MD PhD?
Apply for one of the trials that Aasef G. Shaikh, MD PhD is conducting.
What is the office address of Aasef G. Shaikh, MD PhD?
The office of Aasef G. Shaikh, MD PhD is located at: Louis Stokes VA Medical Center, Cleveland, OH, Cleveland, Ohio 44106-1702 United States. This is the address for their practice at the Louis Stokes VA Medical Center, Cleveland, OH.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.