Dr. Arthur F Gelb, MD

Claim this profile

Arthur F Gelb MD

Studies Asthma
Studies Pneumonia
4 reported clinical trials
13 drugs studied

Affiliated Hospitals

Image of trial facility.

Arthur F Gelb MD

Image of trial facility.

Arthur F Gelb Medical Corporation

Clinical Trials Arthur F Gelb, MD is currently running

Image of trial facility.

Inhaled Corticosteroids and Beta2 Agonists

for Asthma

The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction. Treatment will include inhaled corticosteroids and long acting beta2agonists and long acting muscarinic antagonists. We are interested in determining whether the large and/or small airways are the predominant site of airflow limitation. We are also interested in determining whether intrinsic small airways obstruction and/or loss of lung elastic recoil is responsible for expiratory airflow limitation and to what extent may be attributed to loss of lung elastic recoil vs decreased airway conductance in peripheral airways. We are also interested to evaluate the role of varying doses of inhaled corticosteroids to suppress large and small airway inflammation using exhaled nitric oxide as surrogate markers of inflammation. For comparison purposes, spirometry and measurements of exhaled nitric oxide will also be obtained if possible during a naturally occurring exacerbation of asthma. High resolution thin section CT of the lung will also be obtained. Analysis will evaluate integrity of the lung parenchyma as to absence and or presence of emphysema and extent of emphysema using voxel quantification. We will also investigate optical coherence tomography to detect clinically unsuspected emphysema. We will also obtain autopsy material when available in asthmatics who expire. Will also measure serum periostin as a marker of inflammation by collaborating with Genetech in San Francisco.

Recruiting

2 awards

N/A

4 criteria

Image of trial facility.

Detection of Airways Obstruction

for Cystic Fibrosis

Goal is to physiologically detect unsuspected small airways obstruction in children and adults with treated heterozygous and homozygous cystic fibrosis. Unsuspected refers to normal routine pre bronchodilator spirometry including normal FEV1(L), FVC (L). and FEV1/FVC%. This is a retrospective study.

Recruiting

1 award

N/A

1 criteria

More about Arthur F Gelb, MD

Clinical Trial Related

18 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Arthur F Gelb, MD has experience with

  • Budesonide/Formoterol
  • Fluticasone/Salmeterol
  • Inhaled Corticosteroid
  • Long Acting Inhaled Beta2 Agonist
  • Long Acting Inhaled Muscarinic Receptor Antagonist
  • Oral Antibiotic

Other Doctors you might be interested in

Frequently asked questions

Do I need insurance to participate in a trial?

What does Arthur F Gelb, MD specialize in?

Is Arthur F Gelb, MD currently recruiting for clinical trials?

Are there any treatments that Arthur F Gelb, MD has studied deeply?

What is the best way to schedule an appointment with Arthur F Gelb, MD?

What is the office address of Arthur F Gelb, MD?

Is there any support for travel costs?