Dr. Asokumar Buvanendran, MD
Claim this profileRush University Medical Center
Studies Neuropathic Pain
Studies Driving Performance After Minor Ambulatory Surgery
4 reported clinical trials
9 drugs studied
Affiliated Hospitals
Clinical Trials Asokumar Buvanendran, MD is currently running
Hydroxynorketamine
for Neuropathic Pain
The goal of this randomized double blind three way (1:1:1) cross over clinical trial is to evaluate the effectiveness and duration of analgesia of a single infusion of (2R,6R)-HNK 0.5mg/kg compared with ketamine 0.5mg/kg and saline with a 5-week interval between treatments on pain, pain qualities, physical function, pain interference, sleep disturbance and quality of life in subjects with neuropathic pain of the extremities. The questions that this study will address are: 1. What is the analgesic efficacy of (2R,6R)-HNK on pain intensity and pain qualities in patients with chronic (\>3 month) neuropathic pain (NP). 2. What will be the effective duration of a single infusion of (2R,6R)-HNK in patients with NP. 3. Will (2R,6R)-HNK reduce pain related effects including interference in daily activities of life, sleep disturbances and change the qualities of pain reported by patients. Participants will receive each of the three study drugs in a random order at 5-week intervals over a 15 week period. The drug will be administered as a 45-minute infusion. Participants will complete quantitative sensory and pain evaluations and complete patient reported pain outcomes prior to receiving the first study drug and at 7, 14 and 21 and 35 days following study drug administration.
Recruiting0 awards Phase 1 & 211 criteria
Ketamine
for Postoperative Pain
The study utilizes a 3-arm placebo-controlled RCT to study the effectiveness of ketamine in reducing chronic post-mastectomy pain. Participants randomized to the first arm will receive a 0.35 mg/kg dose after induction, followed by a 0.25 mg/kg/hr infusion during surgery (up to a maximum of 6 hours) and continued for 2 hours postoperatively. Participants in the second arm will receive a single dose of 0.6 mg/kg of ketamine in the post-anesthesia care unit, and the final group will serve as the control group and receive saline (no ketamine).
Recruiting1 award Phase 33 criteria
More about Asokumar Buvanendran, MD
Clinical Trial Related1 year of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Asokumar Buvanendran, MD has experience with
- Ketamine
- (2R,6R)-hydroxynorketamine
- Saline
- Midazolam
- Propofol
- Sufentanil
Breakdown of trials Asokumar Buvanendran, MD has run
Neuropathic Pain
Driving Performance After Minor Ambulatory Surgery
Postoperative Pain
Chronic Pain
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Asokumar Buvanendran, MD specialize in?
Asokumar Buvanendran, MD focuses on Neuropathic Pain and Driving Performance After Minor Ambulatory Surgery. In particular, much of their work with Neuropathic Pain has involved treating patients, or patients who are undergoing treatment.
Is Asokumar Buvanendran, MD currently recruiting for clinical trials?
Yes, Asokumar Buvanendran, MD is currently recruiting for 2 clinical trials in Chicago Illinois. If you're interested in participating, you should apply.
Are there any treatments that Asokumar Buvanendran, MD has studied deeply?
Yes, Asokumar Buvanendran, MD has studied treatments such as Ketamine, (2R,6R)-hydroxynorketamine, Saline.
What is the best way to schedule an appointment with Asokumar Buvanendran, MD?
Apply for one of the trials that Asokumar Buvanendran, MD is conducting.
What is the office address of Asokumar Buvanendran, MD?
The office of Asokumar Buvanendran, MD is located at: Rush University Medical Center, Chicago, Illinois 60612 United States. This is the address for their practice at the Rush University Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.