Dr. Falkson Carla, MD

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The University of Alabama at Birmingham

Studies Neuroinflammatory Disease
Studies Breast Cancer
1 reported clinical trial
2 drugs studied

Area of expertise

1Neuroinflammatory Disease
Falkson Carla, MD has run 1 trial for Neuroinflammatory Disease. Some of their research focus areas include:
Stage II
Stage III
2Breast Cancer
Falkson Carla, MD has run 1 trial for Breast Cancer. Some of their research focus areas include:
Stage II
Stage III

Affiliated Hospitals

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The University Of Alabama At Birmingham

Clinical Trials Falkson Carla, MD is currently running

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PET Scans

for Brain Inflammation in Breast Cancer

This clinical study will use the small molecule translocator protein (TSPO) ligand, 18F-labeled DPA-714, to visualize and quantify neuroinflammation in treatment naive women with stage II-III newly diagnosed breast cancer (without brain metastases) prior to starting neoadjuvant chemotherapy treatment (baseline) and within 4 weeks after finishing neoadjuvant chemotherapy (NACT) with at least 2 cycles administered and before surgery. . The TSPO PET and MRI data acquired through this study will be correlated with cognitive test data, clinical data, and genetic testing collected in this study. We will enroll 20 participants in this study (20 participants with breast cancer). Study Aim 1: To examine the association between neuroinflammation and cancer related cognitive impairment (CRCI) in women with breast cancer before and after undergoing chemotherapy treatment. (Hypothesis 1): Treatment-naïve women with Stage II-III breast cancer (without known brain metastases) will experience increased amount of neuroinflammation and greater cognitive decline after completing neodjuvant Chemotherapy Treatment (NACT). (Hypothesis 2): Greater levels of neuroinflammation as measured by the amount and distribution of \[18F\]DPA-714 in the brain using PET/MRI after completing NACT will be associated with lower levels of cognitive functioning as measured by self-report and/or objective cognitive impairment/change. Neuroinflammation will be measured using PET with tracer \[18F\]DPA-714 using a simultaneous PET/MRI system, and cognitive functioning will be measured with self-report and objective neuropsychological measures. Exploratory Aim 2: To investigate the relationships between CRCI and quality of life (QOL) and everyday functioning in breast cancer survivors after completing chemotherapy treatment. For this Aim, we will assess QOL using self-report measures.
Recruiting1 award Phase 1

More about Falkson Carla, MD

Clinical Trial Related1 year of experience running clinical trials · Led 1 trial as a Principal Investigator · 1 Active Clinical Trial
Treatments Falkson Carla, MD has experience with
  • [11C]PiB
  • 18F-labeled DPA-714
Breakdown of trials Falkson Carla, MD has run
Neuroinflammatory Disease
Breast Cancer
Cognitive Impairment

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Frequently asked questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Falkson Carla, MD specialize in?
Falkson Carla, MD focuses on Neuroinflammatory Disease and Breast Cancer. In particular, much of their work with Neuroinflammatory Disease has involved Stage II patients, or patients who are Stage III.
Is Falkson Carla, MD currently recruiting for clinical trials?
Yes, Falkson Carla, MD is currently recruiting for 1 clinical trial in Birmingham Alabama. If you're interested in participating, you should apply.
Are there any treatments that Falkson Carla, MD has studied deeply?
Yes, Falkson Carla, MD has studied treatments such as [11C]PiB, 18F-labeled DPA-714.
What is the best way to schedule an appointment with Falkson Carla, MD?
Apply for one of the trials that Falkson Carla, MD is conducting.
What is the office address of Falkson Carla, MD?
The office of Falkson Carla, MD is located at: The University of Alabama at Birmingham, Birmingham, Alabama 35249 United States. This is the address for their practice at the The University of Alabama at Birmingham.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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