Dr. Heidi McKean
Claim this profileAvera Cancer Institute
Studies Colorectal Cancer
Studies Tumors
9 reported clinical trials
23 drugs studied
Area of expertise
1Colorectal Cancer
Stage III
Stage IV
HER2 positive
2Tumors
dMMR positive
MSI-H positive
Stage III
Affiliated Hospitals
Clinical Trials Heidi McKean is currently running
Tucatinib + Trastuzumab + Chemotherapy
for Colorectal Cancer
This study is being done to find out if tucatinib with other cancer drugs works better than standard of care to treat participants with HER2 positive colorectal cancer. This study will also determine what side effects happen when participants take this combination of drugs. A side effect is anything a drug does to the body besides treating your disease. Participants in this study have colorectal cancer that has spread through the body (metastatic) and/or cannot be removed with surgery (unresectable). Participants will be assigned randomly to the tucatinib group or standard of care group. The tucatinib group will get tucatinib, trastuzumab, and mFOLFOX6. The standard of care group will get either: * mFOLFOX6 alone, * mFOLFOX6 with bevacizumab, or * mFOLFOX6 with cetuximab mFOLFOX6 is a combination of multiple drugs. All of the drugs given in this study are used to treat this type of cancer.
Recruiting2 awards Phase 3
Chemotherapy + Immunotherapy
for Esophageal and Gastric Cancer
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
More about Heidi McKean
Clinical Trial Related1 year of experience running clinical trials · Led 9 trials as a Principal Investigator · 8 Active Clinical TrialsTreatments Heidi McKean has experience with
- Oxaliplatin
- MFOLFIRINOX
- Modakafusp Alfa
- Pembrolizumab
- Tucatinib
- Trastuzumab
Breakdown of trials Heidi McKean has run
Colorectal Cancer
Tumors
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Heidi McKean specialize in?
Heidi McKean focuses on Colorectal Cancer and Tumors. In particular, much of their work with Colorectal Cancer has involved Stage III patients, or patients who are Stage IV.
Is Heidi McKean currently recruiting for clinical trials?
Yes, Heidi McKean is currently recruiting for 7 clinical trials in Sioux Falls South Dakota. If you're interested in participating, you should apply.
Are there any treatments that Heidi McKean has studied deeply?
Yes, Heidi McKean has studied treatments such as Oxaliplatin, mFOLFIRINOX, Modakafusp Alfa.
What is the best way to schedule an appointment with Heidi McKean?
Apply for one of the trials that Heidi McKean is conducting.
What is the office address of Heidi McKean?
The office of Heidi McKean is located at: Avera Cancer Institute, Sioux Falls, South Dakota 57105 United States. This is the address for their practice at the Avera Cancer Institute.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.