Dr. Jonathan B Ashman, M.D.

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Mayo Clinic in Arizona

Studies Hepatocellular Carcinoma
Studies Liver Cancer
4 reported clinical trials
12 drugs studied

Affiliated Hospitals

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Mayo Clinic In Arizona

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Mayo Clinic

Clinical Trials Jonathan B Ashman, M.D. is currently running

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Radiotherapy + Chemotherapy

for Esophageal Cancer

This phase II trial tests how well preoperative (prior to surgery) radiation therapy with fluorouracil, oxaliplatin, and leucovorin calcium (FOLFOX) works for the treatment of stage I-III esophageal or gastroesophageal junction adenocarcinoma. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. Fluorouracil stops cells from making deoxyribonucleic acid (DNA) and it may kill tumor cells. Leucovorin is not a chemotherapy medication but is given in conjunction with chemotherapy. Leucovorin is used with the chemotherapy medication fluorouracil to enhance the effects of the fluorouracil, in other words, to make the drug work better. Oxaliplatin is in a class of medications called platinum-containing antineoplastic agents. It damages the cell's DNA and may kill tumor cells. Giving preoperative hypofractionated radiation with fluorouracil and oxaliplatin may kill more tumor cells in patients with stage I-III esophageal or gastroesophageal junction adenocarcinoma.

Recruiting

1 award

Phase 2

9 criteria

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Carbon Ion Therapy vs Surgery vs Proton Therapy

for Bone Cancer

This study compares carbon ion therapy, surgery, and proton therapy to determine if one has better disease control and fewer side effects. There are three types of radiation treatment used for pelvic bone sarcomas: surgery with or without photon/proton therapy, proton therapy alone, and carbon ion therapy alone. The purpose of this study is to compare quality of life among patients treated for pelvic bone sarcomas across the world, and to determine if carbon ion therapy improves quality of life compared to surgery and disease control compared with proton therapy.

Recruiting

1 award

N/A

8 criteria

More about Jonathan B Ashman, M.D.

Clinical Trial Related

4 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Jonathan B Ashman, M.D. has experience with

  • Proton Stereotactic Body Radiation Therapy
  • Bevacizumab
  • Epacadostat
  • Radiation Therapy
  • Retifanlimab
  • Fluorouracil

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