Trial Summary
What is the purpose of this trial?This phase II trial studies the effect of stereotactic body proton radiotherapy in treating patients with liver cancer. Proton radiotherapy is a type of treatment that uses high-energy beams to treat tumors.
Eligibility Criteria
Adults with newly diagnosed or recurrent liver cancer, specifically hepatocellular carcinoma without metastases. They can have up to three treatable lesions and may have had prior local treatments. Participants should be in relatively good health (ECOG 0-2), with a life expectancy of at least 3 months, adequate blood counts, and no severe illnesses that could interfere with the study.Inclusion Criteria
Absolute neutrophil count (ANC) >= 1000 cells/mm^3 (within 45 days of study entry)
My breast cancer is at an early or localized stage.
Able to and provides Institutional Review Board (IRB) approved study specific written informed consent
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Exclusion Criteria
I am a woman who can have children and do not use birth control.
I cannot receive radiotherapy due to health reasons.
My liver has more than 3 highly likely cancerous lesions or too much disease for safe treatment.
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Participant Groups
The trial is testing stereotactic body proton radiotherapy for liver cancer treatment. This non-invasive method uses precise high-energy proton beams aimed at tumors to minimize damage to surrounding healthy tissue. The study will assess its effectiveness and impact on patients' quality of life.
1Treatment groups
Experimental Treatment
Group I: Treatment (SBPT)Experimental Treatment2 Interventions
Patients undergo 1 SBPT fraction over 20-30 minutes per day for a total of 5 fractions.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Mayo Clinic in RochesterRochester, MN
Mayo Clinic in ArizonaScottsdale, AZ
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Who Is Running the Clinical Trial?
Mayo ClinicLead Sponsor
National Cancer Institute (NCI)Collaborator