Kedar Kirtane | Moffitt

Dr. Kedar Kirtane, MD

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Moffitt Cancer Center

Studies Squamous Cell Carcinoma
Studies Cancer
10 reported clinical trials
21 drugs studied

Area of expertise

1

Squamous Cell Carcinoma

Kedar Kirtane, MD has run 4 trials for Squamous Cell Carcinoma. Some of their research focus areas include:

Stage IV
PD-L1 positive
p16 positive
2

Cancer

Kedar Kirtane, MD has run 4 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
HLA-A positive

Affiliated Hospitals

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Moffitt Cancer Center

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Moffitt Cancer Center - McKinley Campus

Clinical Trials Kedar Kirtane, MD is currently running

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CAR T-Cell Preparation

for Cancer

Objective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect and store an eligible participant's own T cells for future use to make CAR T-Cell therapy for their disease treatment. Design: This is a non-interventional, observational study to evaluate participants with solid tumors with a high risk of relapse for incurable disease. No interventional therapy will be administered on this study. Some of the information regarding the participant's tumor analysis may be beneficial to management of their disease. Participants that meet all criteria may be enrolled and leukapheresed (blood cells collected). The participant's cells will be processed and stored for potential manufacture of CAR T-cell therapy upon relapse of their cancer.

Recruiting

1 award

N/A

3 criteria

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Pembrolizumab + Radiation vs Chemotherapy + Radiation

for Head and Neck Cancer

This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiation therapy) after surgery in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or patients with a second head and neck cancer that is not from metastasis (primary). Radiation therapy uses high energy radiation or protons to kill tumor cells and shrink tumors. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of cancer cells. Carboplatin is also in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of cancer cells. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab alone after surgery may work better than the usual approach in shrinking recurrent or primary head and neck squamous cell carcinoma.

Recruiting

1 award

Phase 2

31 criteria

More about Kedar Kirtane, MD

Clinical Trial Related

4 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 5 Active Clinical Trials

Treatments Kedar Kirtane, MD has experience with

  • Pembrolizumab
  • Cisplatin
  • Aldesleukin
  • Cyclophosphamide
  • Fludarabine
  • Platinum Based Chemotherapy

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