Dr. Dr. Peter Metrakos, MD, Surgery
Claim this profileRoyal Victoria Hospital, McGill University Health Centre
Affiliated Hospitals
Royal Victoria Hospital, McGill University Health Centre
Royal Victoria Hospital
Clinical Trials Dr. Peter Metrakos, MD, Surgery is currently running
High-Dose Insulin Therapy
for Liver Regeneration
The primary objective of this interventional study is determine if the future liver remnant can be optimized by improving liver function pre-operatively in patients who are scheduled for major hepatectomy. The main questions it aims to answer are: 1. Does high-dose insulin therapy improve liver function in the pre-operative setting? 2. What is the effect of high-dose insulin therapy on liver function and liver regeneration after a liver venous deprivation (LVD) procedure? 3. What is the relationship between volume hypertrophy and function in the regenerating liver? Participants will receive a 6-hour infusion of insulin and dextrose to maintain a hyperinsulinemic-normoglycemic state in the weeks prior to planned liver surgery to assess its effect on liver function measured by 99m-Tc-Mebrofenin hepatobiliary scintigraphy.
Recruiting
1 award
N/A
3 criteria
High Dose Insulin
for Surgical Site Infections
Despite improvements in surgical techniques and perioperative care, the high incidence of postoperative surgical site infections remains a major problem in patients undergoing major abdominal surgery (liver, pancreatic and colorectal surgery). Using the hyperinsulinemic-normoglycemic clamp technique, i.e. continuous infusion of insulin combined with dextrose titrated to "clamp" blood glucose between 4 and 6 mmol/L, we successfully established and preserved normoglycemia during the perioperative period. Our objective of this study is to determine if the maintenance of perioperative normoglycemia by a hyperinsulinemic normoglycemic clamp reduces the rates of incisional and space/ surgical site infections following abdominal surgery (liver, pancreatic and colorectal surgery).
Recruiting
0 awards
N/A
More about Dr. Peter Metrakos, MD, Surgery
Clinical Trial Related
2 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Dr. Peter Metrakos, MD, Surgery has experience with
- Hyperinsulinemic Normoglycemic Clamp
- Hyperinsulinemic Normoglycemic Clamp
- Standard Glucose Management
- Liver Resection
- Preoperative Glucose Infusion
- Preoperative Normal Saline Infusion
Breakdown of trials Dr. Peter Metrakos, MD, Surgery has run
Postoperative Complications
Insulin Resistance
Infections and Infestations
Wound Infection
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Dr. Peter Metrakos, MD, Surgery specialize in?
Dr. Peter Metrakos, MD, Surgery focuses on Postoperative Complications and Insulin Resistance. In particular, much of their work with Postoperative Complications has involved treating patients, or patients who are undergoing treatment.
Is Dr. Peter Metrakos, MD, Surgery currently recruiting for clinical trials?
Yes, Dr. Peter Metrakos, MD, Surgery is currently recruiting for 2 clinical trials in Montreal Quebec. If you're interested in participating, you should apply.
Are there any treatments that Dr. Peter Metrakos, MD, Surgery has studied deeply?
Yes, Dr. Peter Metrakos, MD, Surgery has studied treatments such as Hyperinsulinemic Normoglycemic Clamp, Hyperinsulinemic normoglycemic clamp, Standard glucose management.
What is the best way to schedule an appointment with Dr. Peter Metrakos, MD, Surgery?
Apply for one of the trials that Dr. Peter Metrakos, MD, Surgery is conducting.
What is the office address of Dr. Peter Metrakos, MD, Surgery?
The office of Dr. Peter Metrakos, MD, Surgery is located at: Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec H3A 1A1 Canada. This is the address for their practice at the Royal Victoria Hospital, McGill University Health Centre.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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