Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection
RL
Overseen byRalph Lattermann, MD PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre
Trial Summary
What is the purpose of this trial?
The goal of the study is to determine whether intravenous glucose administration before liver resection preserves hepatic glycogen resulting in improved hepatic metabolic function after the operation. We further investigate whether the benefit of avoiding preoperative fasting is more pronounced in patients undergoing more extensive liver resection.
Research Team
RL
Ralph Lattermann, MD PhD
Principal Investigator
Department of Anaesthesia, McGill University Health Centre
Eligibility Criteria
Inclusion Criteria
American Society of Anesthesiologists class ≤3
liver resection (one or more liver segments) for primary or secondary malignancy
ability to give informed consent
Treatment Details
Interventions
- Liver Resection (Procedure)
- Preoperative glucose infusion (Other)
- Preoperative normal saline infusion (Other)
Participant Groups
2Treatment groups
Active Control
Placebo Group
Group I: 1Active Control1 Intervention
Glucose infusion.
Group II: 2Placebo Group1 Intervention
Normal saline infusion.
Find a Clinic Near You
Who Is Running the Clinical Trial?
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead Sponsor
Trials
476
Recruited
170,000+