Sascha Alexander Tuchman, MD, MHS ...

Dr. Sascha Tuchman, MD

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UNC Lineberger Comprehensive Cancer Center

Studies Multiple Myeloma
Studies Amyloidosis
9 reported clinical trials
12 drugs studied

Area of expertise

1

Multiple Myeloma

Sascha Tuchman, MD has run 9 trials for Multiple Myeloma. Some of their research focus areas include:

Stage III
Stage IV
2

Amyloidosis

Sascha Tuchman, MD has run 3 trials for Amyloidosis.

Affiliated Hospitals

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UNC Lineberger Comprehensive Cancer Center

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University Of North Carolina

Clinical Trials Sascha Tuchman, MD is currently running

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Iberdomide

for Multiple Myeloma

This phase II trial compares iberdomide maintenance therapy to disease monitoring for improving survival in patients who have received idecabtagene vicleucel (a type of chimeric antigen receptor T-cell \[CAR-T\] therapy) for multiple myeloma. The usual approach after treatment with idecabtagene vicleucel is to monitor the multiple myeloma without giving myeloma medications. There is currently no medication approved specifically for use after idecabtagene vicleucel treatment. Upon administration, iberdomide modifies the immune system and activates immune cells called T-cells, which could enhance the effectiveness of idecabtagene vicleucel. Iberdomide may keep multiple myeloma under control for longer than the usual approach (disease monitoring) after idecabtagene vicleucel, and may help multiple myeloma patients live longer.

Recruiting

1 award

Phase 2

10 criteria

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Isa-Rd Combo Therapy

for Multiple Myeloma

This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than is currently standard for these drugs. Lower doses will be used to avoid or possibly reduce any unwanted side effects commonly associated with these drugs. Using lower doses of the combination isatuximab, lenalidomide and dexamethasone, has not been approved by the Food and Drug Administration (FDA) for the treatment of newly diagnosed MM.

Recruiting

1 award

Phase 2

10 criteria

More about Sascha Tuchman, MD

Clinical Trial Related

5 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 5 Active Clinical Trials

Treatments Sascha Tuchman, MD has experience with

  • Lenalidomide
  • Dexamethasone
  • Isatuximab
  • Iberdomide
  • Idecabtagene Vicleucel
  • Ixazomib

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