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Yasmin vs Yaz
Introduction
For females seeking contraception, hormonal birth control pills like Yasmin and Yaz are commonly recommended. These medications function by modulating the levels of certain hormones in the body, which can inhibit ovulation and alter the uterine lining to prevent pregnancy. Both Yasmin and Yaz contain drospirenone (a synthetic version of progesterone) and ethinyl estradiol (a form of estrogen). However, their formulations slightly differ. While both have 21 active pills, Yasmin's seven inactive pills do not contain any hormones while Yaz has four hormone-free days but includes an additional three days with a low dose of estrogen. This altered schedule can result in fewer hormonal fluctuations for some women when taking Yaz compared to Yasmin.
Yasmin vs Yaz Side By Side
| Attribute | Yasmin | Yaz |
|---|---|---|
| Brand Name | Yasmin | Yaz |
| Contraindications | Allergic reactions to ingredients, smokers over 35 years old, liver disease, history of blood clots | Allergic reactions to ingredients, smokers over 35 years old, liver disease, history of blood clots |
| Cost | Around $100 for a one-month supply (28 tablets) or $20 to $45 for the generic version | Around $110 for a one-month supply (28 tablets) or $25 to $50 for the generic version |
| Generic Name | Drospirenone/ethinyl estradiol | Drospirenone/ethinyl estradiol |
| Most Serious Side Effect | Cardiovascular complications such as blood clots, stroke, heart attack | Cardiovascular complications such as blood clots, stroke, heart attack |
| Severe Drug Interactions | Anticonvulsants, barbiturates, St. John's Wort | Anticonvulsants, barbiturates, St. John's Wort |
| Typical Dose | One pill per day for 28 days | One pill per day for 24 consecutive days, followed by one inactive pill per day for the next four days |
What is Yasmin?
Drospirenone/ethinyl estradiol (the generic name for Yasmin) was a breakthrough in the category of combined oral contraceptives when it was first approved by the FDA in 2001. Yasmin increases levels of sex hormones that prevent ovulation, effectively "trapping" them in the body and creating a state similar to pregnancy, thereby preventing actual conception from occurring. It is prescribed for birth control purposes as well as treating moderate acne and premenstrual dysphoric disorder (PMDD).
Yasmin has a selective influence on progesterone receptors with only minor influence on other steroid hormone receptors, which results in it having fewer side effects than older contraceptives that have stronger effects on these other receptors.
Its sibling drug Yaz has a similar mechanism but differs slightly in hormonal balance and usage indications: Yaz contains less ethinyl estradiol per tablet and is taken over a shorter cycle (24 active pill days versus Yasmin's 21), making its hormonal effect more consistent throughout the month.
What conditions is Yasmin approved to treat?
Yasmin and Yaz are both approved for specific purposes:
- Yasmin is used as a contraceptive to prevent pregnancy, and also helps treat moderate acne for those who choose it as a method of birth control.
- Yaz, on the other hand, besides being utilized as a contraceptive, is additionally approved to help manage symptoms of premenstrual dysphoric disorder (PMDD) in women choosing it for birth control. It can also be used to treat moderate acne for women at least 14 years old if they have started menstruating.
How does Yasmin help with these illnesses?
Yasmin and Yaz are both oral contraceptives that regulate a woman's menstrual cycle to prevent pregnancy. They do this by providing a consistent level of synthetic hormones, namely estrogen (ethinyl estradiol) and progestin (drospirenone), which mimic the hormones naturally produced in a woman's body. These steady hormone levels induce the body into thinking it is already pregnant, thereby preventing actual ovulation from occurring.
In addition to their contraceptive function, Yasmin and Yaz also have secondary uses such as treating moderate acne or symptoms of premenstrual dysphoric disorder in women who choose these pills for birth control.
The primary difference between Yasmin and Yaz lies in the amount of ethinyl estradiol each pill contains per dosage unit: Yasmin contains 30 micrograms while Yaz contains slightly less at 20 micrograms. This small variation can make a significant impact on how well an individual tolerates one pill over another since some women may be more sensitive to hormonal fluctuations. Thus, by adjusting the levels of synthetic hormones provided, both Yasmin and Yaz provide options for women seeking effective contraception with minimized side effects.
What is Yaz?
Yaz is a brand name for drospirenone/ethinyl estradiol, a combination drug that acts as an oral contraceptive by inhibiting ovulation and altering the cervical mucus and endometrium. It also contains drospirenone, which is a progestin with anti-mineralocorticoid activity meaning it can reduce fluid-related symptoms. Yaz was first approved by the FDA in 2006. As Yaz is not just an estrogen-containing contraceptive like Yasmin, its formulation has some unique advantages. Its lack of action on mineralocorticoids leads to less water retention and hence less weight gain (a common side effect of hormonal contraceptives such as Yasmin). The presence of ethinyl estradiol means it also has fewer risks associated with deep vein thrombosis compared to other combined oral contraceptives. Moreover, thanks to its specific formulation, Yaz may be more beneficial for patients who suffer from premenstrual dysphoric disorder or acne vulgaris conditions often worsened by “typical” hormonal birth control pills such as Yasmin.
What conditions is Yaz approved to treat?
Yaz is an approved oral contraceptive that can be used not just for the prevention of pregnancy, but also for:
- Treating symptoms of premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome.
- Treatment and management of moderate acne in women who are at least 14 years old and have started having menstrual periods.
How does Yaz help with these illnesses?
Drospirenone is a synthetic form of progesterone, also known as a progestin. It plays key roles in many female reproductive processes, affecting menstrual cycles, pregnancy, and lactation. In combination with ethinyl estradiol, it forms the basis for Yaz contraceptive pills. The function of Yaz revolves around inhibiting ovulation by altering hormone levels in your body to prevent egg release from ovaries; hence preventing pregnancy. Additionally, drospirenone exhibits anti-mineralocorticoid activity which might be beneficial for women who suffer from water retention or bloating due to hormonal imbalance during their menstrual cycle. This makes Yaz an effective choice not only for contraception but also for managing premenstrual dysphoric disorder (PMDD) and acne in certain cases where Yasmin may not be as suitable or well-tolerated. Since it contains slightly lower estrogen dose compared to Yasmin (20 mcg versus 30 mcg), it may have fewer side effects related to estrogen such as nausea and breast tenderness.
How effective are both Yasmin and Yaz?
Both Yasmin and Yaz are contraceptive pills with established histories of success in preventing pregnancy, having been approved by the FDA in 2001 and 2006 respectively. Both medications contain a combination of drospirenone (a progestin) and ethinyl estradiol (an estrogen), but they differ slightly in their formulation: Yasmin contains 0.03 mg of ethinyl estradiol per pill while Yaz contains a lower dose at 0.02 mg.
The effectiveness of both contraceptives has been extensively studied, showing similar efficacy rates for pregnancy prevention when taken as directed - around 99%. A study published in Contraception Journal compared the two drugs' safety profiles; it found that both had comparable side effects including nausea, irregular menstrual bleeding, weight gain and breast tenderness.
A review from Cochrane Database demonstrated that combined oral contraceptives like Yasmin or Yaz are effective starting from the first month of use with favorable side effect profiles over other methods. The same study reports that these forms have become some of the most widely prescribed contraceptive methods worldwide due to their reliability and non-invasive nature.
Yaz is also approved for treating premenstrual dysphoric disorder (PMDD) and acne vulgaris due to its unique hormone combination; whereas Yasmin does not hold these specific indications though off-label prescribing may occur based on individual patient needs or preferences. Nonetheless, because every woman's body reacts differently to hormonal changes caused by birth control pills such as these, it is important to discuss your personal medical history with your healthcare provider before choosing which one is best for you.
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At what dose is Yasmin typically prescribed?
Oral dosages of Yasmin and Yaz are typically one pill per day, taken at the same time each day for 28 days. However, while both contain ethinyl estradiol and drospirenone, Yasmin contains a slightly higher dose of ethinyl estradiol than Yaz. This difference in hormone levels may affect how individuals react to each medication. Both medications should be started on the first day of your menstrual cycle or on the first Sunday after your period begins. If there is no response or if side effects occur after a few weeks, you should consult with your healthcare provider about adjusting dosage or switching medications. It's important not to exceed taking more than one pill per day unless directed by a healthcare professional.
At what dose is Yaz typically prescribed?
Yaz treatment typically begins with a dosage of one pill per day for 24 consecutive days, followed by one inactive (placebo) pill per day for the following four days. The pills should be taken at approximately the same time each day and it is recommended to not skip any doses. If Yaz seems ineffective or if adverse reactions occur, consultation with a healthcare professional is advised before making any changes to the regimen. It's important to note that Yaz contains fewer active pills and more placebo pills than Yasmin, which may lead to shorter menstrual periods.
What are the most common side effects for Yasmin?
Common side effects of Yasmin and Yaz include:
- Nausea, vomiting
- Breast tenderness or swelling
- Headaches or migraines
- Changes in weight or appetite (weight gain)
- Vaginal bleeding between periods (spotting) or missed/irregular menstrual periods
- Decreased sex drive (libido)
- Mood changes, anxiety, depression, irritability
- Increased blood pressure
- Swelling of the ankles/feet (fluid retention)
Remember that each individual can react differently to medication. If any of these side effects persist or worsen, it's essential you seek medical help promptly.
Are there any potential serious side effects for Yasmin?
While both Yasmin and Yaz are considered safe for most users, they can cause serious side effects in rare cases. These include:
- An allergic reaction, which may manifest as difficulty breathing; swelling of the face, lips, tongue or throat; hives; or a rash.
- Changes in vision: visual disturbances like blurred vision or seeing halos around lights could be signs of fluid buildup in the eye.
- Cardiovascular complications such as blood clots, stroke, heart attack. Symptoms include sudden dizziness or fainting; sharp chest pain radiating to your jaw or shoulder; coughing up blood; severe headache with numbness on one side of your body and slurred speech.
- Unusually high levels of potassium - symptoms could include muscle weakness, irregular heartbeat and altered mental states like confusion and lethargy.
In addition to these common symptoms between both drugs:
Yasmin-specific reactions might also involve depression-like symptoms including persistent sadness, loss of interest in activities you once enjoyed and thoughts about suicide.
For those taking Yaz: watch out for any serotonin syndrome symptoms such as hallucinations, fever or excessive sweating, shivering muscles stiffness twitching nausea vomiting diarrhea etc.
If you experience any of these adverse effects while taking either medication stop using it immediately consult health care professional promptly
What are the most common side effects for Yaz?
Yaz, a widely used contraceptive pill, may cause the following side effects:
- Nausea or vomiting
- Stomach bloating or cramping
- Increased appetite which can lead to weight gain
- Headaches and dizziness
- Breast tenderness or enlargement
- Changes in menstrual periods, decreased sex drive
- Frequent urination
- Mood changes such as depression or anxiety.
It's important to consult with your healthcare provider if you experience any of these symptoms while taking Yaz.
Are there any potential serious side effects for Yaz?
While Yaz is generally well-tolerated, it can occasionally lead to severe side effects. These may include:
- Signs of an allergic reaction or severe skin response: hives, itching, fever, swollen glands, difficulty breathing, swelling in your face or throat.
- Unusual changes in mood or behavior: increased depressive thoughts or suicidal ideation.
- Neurological problems: seizures (convulsions).
- Vision issues: blurred vision and eye pain.
- Cardiovascular complications: fast or irregular heartbeats.
If you experience any of these adverse reactions while taking Yaz, seek immediate medical attention. It's also crucial to remember that all oral contraceptives carry a small risk of blood clots which could potentially cause stroke or myocardial infarction. This risk may be more pronounced if you smoke cigarettes and are over the age of 35.
Contraindications for Yasmin and Yaz?
Both Yaz and Yasmin, like all oral contraceptives, can cause side effects in some women. If you notice any severe or unusual reactions such as jaundice (yellowing of the skin or eyes), chest pain or heavy feeling in your chest, sudden numbness or weakness on one side of your body, a change in the severity of migraines, swelling in hands/ankles/feet due to fluid retention and weight gain, please seek immediate medical attention.
Neither Yaz nor Yasmin should be taken if you have had an allergic reaction to any ingredients present in these pills. Always inform your physician about which medications you are taking; certain drugs including but not limited to anticonvulsants, barbiturates, St. John's Wort etc., may decrease their effectiveness leading to breakthrough bleeding and increased risk of pregnancy.
Women above 35 years who smoke are advised against using these oral contraceptives due to increased risk for heart attacks or strokes. Liver disease patients and those with history of blood clot formation need special precaution before starting on either pill.
How much do Yasmin and Yaz cost?
For the brand name versions of these drugs:
- The price of a one-month supply (28 tablets) of Yasmin averages around $100, which works out to about $3.50 per day.
- The price for an equivalent supply of Yaz is slightly higher, averaging at around $110 or approximately $4/day.
Thus, if you are taking daily doses as prescribed by your doctor, Yasmin tends to be less expensive on a per-day treatment basis than Yaz. Please note that cost should not be the primary consideration in determining which birth control pill is right for you; factors like side effects and how well it controls your symptoms also matter significantly.
In terms of generic options:
- Drospirenone/ethinyl estradiol (generic version of Yasmin) costs between $20 and $45 for a one-month supply ($0.70-$1.60/per day).
- Similarly priced, the generic form of Yaz may range from about $25 to $50 for a month's worth ($0.90-$1.75/per day).
Remember though that prices might vary depending upon your location and pharmacy choice.
Popularity of Yasmin and Yaz
Yasmin and Yaz are both popular brands of combination oral contraceptives, containing the same active ingredients: drospirenone (a type of progestin) and ethinylestradiol (a form of estrogen). However, they differ in dosage.
In 2020, Yasmin was prescribed to around 3.5 million people in the United States accounting for approximately 10% of combination birth control pill prescriptions. It has remained a consistently prevalent choice over the past decade with its use remaining relatively stable.
On the other hand, Yaz accounted for nearly 15% of combination contraceptive prescriptions with about 5 million women using it as their preferred method in the US during 2020. Its popularity has seen an increase since its introduction due to added benefits such as alleviating symptoms associated with premenstrual dysphoric disorder and acne management on top of serving as a reliable contraceptive.
Conclusion
Both Yasmin and Yaz are combined oral contraceptives with a long history of usage in preventing unwanted pregnancies. They contain drospirenone, a synthetic progestin, and ethinyl estradiol, an estrogen. Their effectiveness is backed by numerous clinical studies showing they are more effective than non-hormonal contraceptive methods.
Yasmin and Yaz differ slightly in the amount of ethinyl estradiol each pill contains; Yasmin has slightly more. This can lead to different side effect profiles between the two drugs, with some women reporting less bloating and water retention on Yaz due to its lower estrogen content.
Both medications also have additional benefits beyond contraception such as reducing acne outbreaks or treating symptoms of premenstrual dysphoric disorder (PMDD), but these uses may be subject to careful consideration by a physician based on individual circumstances.
While both Yasmin and Yaz require prescriptions, generic versions are available which represent significant cost savings for patients who pay out of pocket. Both drugs require strict adherence to daily intake at approximately the same time each day for maximum efficacy.
Side effects for both drugs include nausea, breast tenderness, weight change among others but serious negative effects are rare. Like all hormonal birth control pills though, patients must closely monitor any unusual changes especially during initial use and should consult their healthcare provider if any concerns arise.
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Refrences
- Fenton, C., Wellington, K., Moen, M. D., & Robinson, D. M. (2007). Drospirenone/Ethinylestradiol 3mg/20??g (24/4 Day Regimen). Drugs. Springer Science and Business Media LLC.http://doi.org/10.2165/00003495-200767120-00007
- Taneepanichskul, S., Jaisamrarn, U., & Phupong, V. (2006, November 18). Efficacy of Yasmin in premenstrual symptoms. Archives of Gynecology and Obstetrics. Springer Science and Business Media LLC.http://doi.org/10.1007/s00404-006-0280-6
- Foidart, J.-M. (2005, January). Added benefits of drospirenone for compliance. Climacteric. Informa UK Limited.http://doi.org/10.1080/13697130500330309
- Guang-Sheng, F., Mei-Lu, B., Li-Nan, C., Xiao-Ming, C., Zi-Rong, H., Zi-Yan, H., … Tian-Fu, Y. (2010, June). Efficacy and Safety of the Combined Oral Contraceptive Ethinylestradiol/ Drospirenone (Yasmin®) in Healthy Chinese Women. Clinical Drug Investigation. Springer Science and Business Media LLC.http://doi.org/10.1007/bf03256908
- Kelly, S., Davies, E., Fearns, S., McKinnon, C., Carter, R., Gerlinger, C., & Smithers, A. (2010, May). Effects of Oral Contraceptives Containing Ethinylestradiol with Either Drospirenone or Levonorgestrel on Various Parameters Associated with Well-Being in Healthy Women. Clinical Drug Investigation. Springer Science and Business Media LLC.http://doi.org/10.2165/11535450-000000000-00000
- Oelkers, W. H. K. (2005, January). Drospirenone in combination with estrogens: for contraception and hormone replacement therapy. Climacteric. Informa UK Limited.http://doi.org/10.1080/13697130500330341