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What is Bepotastine Besilate
BepotastineThe Generic name of this drug
Treatment SummaryBepotastine is a medication that blocks the action of histamine, a chemical involved in allergic reactions. Bepotastine was approved in Japan in 2000 and 2002 to treat allergic rhinitis and urticaria/pruritus, respectively. It can be administered orally or as an ophthalmic solution, and it is sold under the brand names Talion and Bepreve. The ophthalmic solution was approved by the FDA in 2009.
Bepreveis the brand name
Bepotastine Besilate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Bepreve
Bepotastine
2009
7
Approved as Treatment by the FDA
Bepotastine, otherwise called Bepreve, is approved by the FDA for 2 uses which include Allergic Conjunctivitis (AC) and Itching .Allergic Conjunctivitis (AC)
Itching
Effectiveness
How Bepotastine Besilate Affects PatientsBepotastine is a drug that works by blocking the histamine 1 (H1) receptor in order to prevent inflammation and allergies. It starts working in about 15 minutes, and its effects can last up to 24 hours. It does not cause side effects like dry mouth or drowsiness, which can be caused by other medications.
How Bepotastine Besilate works in the bodyAllergic conjunctivitis is caused by an allergic reaction in the eyes. Bepotastine helps by blocking the histamine that causes itching, stabilizing the mast cells that cause inflammation, and preventing eosinophils from entering the eye and causing further damage.
When to interrupt dosage
The advocated dose of Bepotastine Besilate is contingent upon the diagnosed malady. The quantity of dosage fluctuates as per the approach of administration (e.g. Solution or Solution / drops - Ophthalmic) outlined in the table beneath.Condition
Dosage
Administration
Itching
, 15.0 mg/mL, 1.5 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Allergic Conjunctivitis (AC)
, 15.0 mg/mL, 1.5 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Warnings
Bepotastine Besilate ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Bepotastine may interact with Pulse Frequency
Common Bepotastine Besilate Drug Interactions
Drug Name
Risk Level
Description
Pitolisant
Major
The therapeutic efficacy of Pitolisant can be decreased when used in combination with Bepotastine.
Aclidinium
Minor
Bepotastine may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Bepotastine may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Bepotastine may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Bepotastine may decrease the excretion rate of Almasilate which could result in a higher serum level.
Bepotastine Besilate Novel Uses: Which Conditions Have a Clinical Trial Featuring Bepotastine Besilate?
19 active clinical trials are currently being conducted to determine the potential of Bepotastine Besilate for the amelioration of Itch.Condition
Clinical Trials
Trial Phases
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Itching
5 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Bepotastine Besilate Reviews: What are patients saying about Bepotastine Besilate?
5Patient Review
5/1/2010 This has been a game-changer for my son. He's only 8, but he had such severe seasonal allergies that it was really impacting his quality of life. This medication has helped him so much.
Patient Q&A Section about bepotastine besilate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of BEPREVE eye drops?
"Symptoms include an unpleasant taste in the mouth, headache, eye irritation, stuffy nose, and sore throat."
Answered by AI
What is BEPREVE prescribed for?
"BEPREVE is a medicine that is used to treat itching that is caused by allergies."
Answered by AI
Do you need a prescription for BEPREVE?
"Bepotastine (Bepreve) is not available over the counter and requires a prescription from a healthcare provider. If you're looking for something over the counter, you may want to try Pataday (olopatadine) or Zaditor (ketotifen), which work similarly to bepotastine (Bepreve)."
Answered by AI
What is bepotastine besilate used for?
"Bepotastine besilate eye drops are used to treat allergic conjunctivitis, which is caused by the body overreacting to substances that it is otherwise harmless. The drops work by preventing the effects of certain inflammatory substances that are produced naturally by the cells in your eyes."
Answered by AI