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What is Thalitone
ChlorthalidoneThe Generic name of this drug
Treatment SummaryChlorthalidone is a medication used to treat high blood pressure and swelling caused by heart or kidney problems. It works by preventing the kidneys from absorbing too much salt and water, which helps reduce blood pressure. Studies have shown that chlorthalidone can reduce the risk of stroke, heart attack, and even death in people with high blood pressure. It is often used as a first-line treatment for hypertension and may be more effective than other medications like beta-blockers, ACE inhibitors, calcium channel blockers, or ARBs. Chlorthalidone has also been shown to reduce platelet aggregation and increase vascular permeability
Chlorthalidoneis the brand name
Thalitone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Chlorthalidone
Chlorthalidone
1981
193
Effectiveness
How Thalitone works in the bodyChlorthalidone stops sodium and chloride from being reabsorbed back into the body. When this happens, fluid is forced out of the body, which lowers blood pressure. Chlorthalidone also helps reduce platelet aggregation and increases the formation of blood vessels, both of which help reduce the risk of cardiovascular disease.
When to interrupt dosage
The suggested measure of Thalitone is contingent upon the determined state, such as Cirrhosis, multiple antihypertensive drugs potentially needed and Swelling. The dosage may also differ according to the technique of delivery noted in the tabular presentation below.Condition
Dosage
Administration
Hypertensive disease
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
Swollen feet or ankles
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
Chronic Kidney Disease (CKD)
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
multiple antihypertensive drugs likely required
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
Congestive Heart Failure
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
not adequately controlled with monotherapy
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
Cirrhosis
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
Nephrolithiasis
, 25.0 mg, 50.0 mg, 15.0 mg, 12.5 mg, 100.0 mg
, Oral, Tablet, Tablet - Oral
Warnings
Thalitone has two prohibitions. If you suffer from any of the conditions in the table below, Thalitone should not be employed.Thalitone ContraindicationsCondition
Risk Level
Notes
Anuria
Do Not Combine
allergic reaction to sulfonamide derivatives
Do Not Combine
Common Thalitone Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Chlorthalidone may increase the hypotensive activities of Amifostine.
Cyclopentamine
Major
The risk or severity of adverse effects can be increased when Chlorthalidone is combined with Cyclopentamine.
Dofetilide
Major
The risk or severity of QTc prolongation can be increased when Chlorthalidone is combined with Dofetilide.
Hexamethonium
Major
The risk or severity of adverse effects can be increased when Chlorthalidone is combined with Hexamethonium.
Lithium carbonate
Major
Chlorthalidone may decrease the excretion rate of Lithium carbonate which could result in a higher serum level.
Thalitone Novel Uses: Which Conditions Have a Clinical Trial Featuring Thalitone?
641 active trials are presently being conducted to assess the effect of Thalitone in managing Kidney Disease, Cirrhosis and Hypertensive Diseases.Condition
Clinical Trials
Trial Phases
Chronic Kidney Disease (CKD)
24 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1
not adequately controlled with monotherapy
0 Actively Recruiting
Cirrhosis
51 Actively Recruiting
Phase 1, Not Applicable, Phase 3, Phase 4, Phase 2, Early Phase 1
multiple antihypertensive drugs likely required
0 Actively Recruiting
Congestive Heart Failure
175 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Swollen feet or ankles
6 Actively Recruiting
Phase 2, Not Applicable
Nephrolithiasis
0 Actively Recruiting
Thalitone Reviews: What are patients saying about Thalitone?
5Patient Review
2/28/2020 I had some initial dizziness when starting this medication, but it quickly subsided and I haven't had any problems since. I've been taking it for almost four years now with no issues.
5Patient Review
2/28/2020 I had some dizziness when I started this medication, but it went away after a few weeks. I've been on the treatment for almost four years now and have had no problems.
5Patient Review
2/28/2020 I had some dizziness when I first started taking this medication, but it eventually went away and I've been taking it for nearly four years now with no problems.
4Patient Review
8/15/2018 This medicine was successful in lowering my blood pressure; however, the chest pain I experience as a side effect sent me to the hospital several times. The feeling is very uncomfortable and left me no choice but to discontinue use of the medication.
4Patient Review
6/4/2022 While this lowered my blood pressure as intended, the side effects were a bit hard to deal with. They included constipation, loss of appetite, and dizziness. The good news is that they improved over time.
Patient Q&A Section about thalitone
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Thalitone prescribed for?
"This can help to lower blood pressure.
Chlorthalidone is used to treat high blood pressure, which can help to prevent strokes, heart attacks, and kidney problems. It is also used to reduce extra salt and water in the body caused by conditions such as heart failure, liver disease, and kidney disease, which can help to lower blood pressure."
Answered by AI
Is Thalitone the same as chlorthalidone?
"Chlorthalidone is a diuretic, meaning it increases the amount of urine you make. This is especially true when you first start the medication. Chlorthalidone also helps relax the blood vessels, which allows blood to flow more easily. It is available under the brand names Hygroton, Thalitone, and Chlorthalid."
Answered by AI
What drug class is Thalitone?
"Thalitone can be used by itself or in combination with other drugs. It is a member of a class of medications known as diuretics, specifically thiazides."
Answered by AI
What is the side effects of chlorthalidone?
"These are all symptoms of a stomach virus."
Answered by AI