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What is Clindamycin Phosphate And Benzoyl Peroxide
Benzoyl peroxideThe Generic name of this drug
Treatment SummaryBenzoyl peroxide is a medication that is used in topical treatments to fight acne. It can be used alone or in combination with other ingredients such as erythromycin, clindamycin, or adapalene. The medication works by breaking down proteins and reducing the amount of keratin and sebum, which can help to reduce acne. Benzoyl peroxide was approved by the FDA in 1984.
Benzamycinis the brand name
Clindamycin Phosphate And Benzoyl Peroxide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Benzamycin
Benzoyl peroxide
1984
79
Effectiveness
How Clindamycin Phosphate And Benzoyl Peroxide Affects PatientsBenzoyl peroxide is a medication used to treat acne. It works by breaking down the existing acne and increasing the rate at which skin cells are replaced. It is generally considered safe, although it can cause skin irritation, dryness, and sunburn. Patients should be aware of these potential side effects and take precautions to avoid them.
How Clindamycin Phosphate And Benzoyl Peroxide works in the bodyAcne is caused by an overproduction of sebum, hormones, and bacteria in the skin. Benzoyl peroxide works to reduce acne by breaking down bacteria, decreasing the amount of sebum, and speeding up the turnover rate of skin cells. This helps to reduce the formation of comedones (whiteheads and blackheads).
When to interrupt dosage
The endorsed dosage of Clindamycin Phosphate And Benzoyl Peroxide is contingent upon the recognized disorder, including Inflammatory Acne Vulgaris, Acne and Acne. The dose shifts, as per the technique of administration (e.g. Solution or Kit - Topical) detailed in the table beneath.Condition
Dosage
Administration
Acne Vulgaris
0.025 mg/mg, , 0.05 mg/mg, 0.1 mg/mg, 25.0 mg/mL, 0.034 mg/mg, 0.0425 mg/mg, 26.0 mg/mL, 50.0 mg/mL, 0.007 mg/mg, 0.05 mg/mL, 0.1 mg/mL, 100.0 mg/mL, 0.005 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 10.0 mg/mL, 25.0 mg, 37.0 mg/mL, 2.75 mg, 0.025 mg/mL, 0.000085 mg/mg, 0.07 mg/mL, 0.06 mg/mg, 0.25 mg/mL, 0.025 mL/mL, 0.053 mg/mg, 0.098 mg/mg, 0.8 mg/mg, 70.0 mg/mL, 0.295 mL/mL, 0.0104 mg/mg, 0.08 mg/mg, 0.05 mL/mL, 0.001 mg/mg, 0.032 mg/mg, 0.09 mg/mg, 0.04 mg/mg, 0.055 mg/mg, 0.318 mg/mg, 0.07 mg/mg, 44.0 mg/mL, 55.0 mg/mL, 0.0525 mg/mg, 42.5 mg/mL, 0.135 mg/mg, 0.22 mg/mL, 0.1 mL/mL, 0.1125 mg/mg, 0.6 mg/mg, 5650.0 mg, 11300.0 mg, 35.0 mg/mL, 0.095 mg/mg, 0.00557 mg/mg, 61.62 mg/mL, 0.329 mg/mg, 30.0 mg/mL, 0.519 mg/mL, 0.3 mL/mL, 0.56 mg/mg, 0.075 mL/mL, 60.0 mg/mL, 90.0 mg/mL, 10.0 %, 5.0 %, 2.5 %, 3.0 %, 4.0 %, 20.0 %, 8.0 %, 3.5 %, 2.6 %, 0.0025 mg/mg, 0.026 mg/mg, 3.7 %, 0.035 mg/mg, 0.1467 mg/mg, 0.03 mg/mg, 0.0587 mg/mg, 52.5 mg/mL, 0.0375 mg/mg, 0.14 mg/mg, 0.15 mg/mg, 45.0 mg/mL, 0.0001 mg/mg, 0.045 mg/mL, 40.0 mg/mL, 200.0 mg/mL, 0.2 mg/mg, 85.0 mg/mL, 0.063 mg/mL, 0.283 mg/mg, 500.0 mg/mL, 60.0 mg, 0.085 mg/mg, 0.0275 mg/mg, 70000.0 mg/mL, 2.5 mg/mL, 0.102 mg/mg, 115.0 mg/mL, 36.9 mg/mL, 0.069 mg/mg, 65.0 mg/mL, 57.5 mg/mL, 0.068 mg/mg, 0.35 mg/mg, 0.5 mg/mg, 0.037 mL/mL, 25000.0 mg/mL, 50000.0 mg/mL, 0.0005 mg/mg, 0.136 mg/mg, 0.1173 mg/mg, 0.085 mg/mL, 0.0948 mg/mg, 0.0625 mg/mg, 9.8 mg/mg, 0.28 mg/mg, 0.075 mg/mL, 0.13 mg/mg, 75.0 mg/mL, 0.125 mg/mg, 0.0025 %/mg, 125.0 mg/mL, 62.0 mg/mL, 50.0 mg
, Lotion, Topical, Lotion - Topical, Kit, Gel, Gel - Topical, Liquid, Liquid - Topical, Cream, Cream - Topical, Solution, Solution - Topical, Swab, Swab - Topical, Aerosol, foam, Aerosol, foam - Topical, Cloth, Cloth - Topical, Emulsion, Emulsion - Topical, Soap, Soap - Topical, Liquid, extended release, Liquid, extended release - Topical, Kit - Topical, Ointment, Ointment - Topical, Suspension, Suspension - Topical, Gel; Lotion, Gel; Lotion - Topical, Paste, Paste - Topical, Jelly, Jelly - Topical, Kit; Lotion; Solution - Topical, Kit; Lotion; Solution, Cream; Gel; Kit; Lotion, Cream; Gel; Kit; Lotion - Topical, Kit; Lotion, Kit; Lotion - Topical, Aerosol, Aerosol - Topical, Gel; Kit; Lotion, Gel; Kit; Lotion - Topical, Gel; Kit, Gel; Kit - Topical, Kit; Liquid; Lotion, Kit; Liquid; Lotion - Topical, Stick - Topical, Stick, Shampoo, suspension, Shampoo, suspension - Topical, Gel; Kit; Paste - Topical, Gel; Kit; Paste, Cream; Kit; Lotion - Topical, Cream; Kit; Lotion, Lotion / shampoo, Lotion / shampoo - Topical, Transdermal, Lotion - Transdermal, Oil - Topical, Oil
Acne Vulgaris
0.025 mg/mg, , 0.05 mg/mg, 0.1 mg/mg, 25.0 mg/mL, 0.034 mg/mg, 0.0425 mg/mg, 26.0 mg/mL, 50.0 mg/mL, 0.007 mg/mg, 0.05 mg/mL, 0.1 mg/mL, 100.0 mg/mL, 0.005 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 10.0 mg/mL, 25.0 mg, 37.0 mg/mL, 2.75 mg, 0.025 mg/mL, 0.000085 mg/mg, 0.07 mg/mL, 0.06 mg/mg, 0.25 mg/mL, 0.025 mL/mL, 0.053 mg/mg, 0.098 mg/mg, 0.8 mg/mg, 70.0 mg/mL, 0.295 mL/mL, 0.0104 mg/mg, 0.08 mg/mg, 0.05 mL/mL, 0.001 mg/mg, 0.032 mg/mg, 0.09 mg/mg, 0.04 mg/mg, 0.055 mg/mg, 0.318 mg/mg, 0.07 mg/mg, 44.0 mg/mL, 55.0 mg/mL, 0.0525 mg/mg, 42.5 mg/mL, 0.135 mg/mg, 0.22 mg/mL, 0.1 mL/mL, 0.1125 mg/mg, 0.6 mg/mg, 5650.0 mg, 11300.0 mg, 35.0 mg/mL, 0.095 mg/mg, 0.00557 mg/mg, 61.62 mg/mL, 0.329 mg/mg, 30.0 mg/mL, 0.519 mg/mL, 0.3 mL/mL, 0.56 mg/mg, 0.075 mL/mL, 60.0 mg/mL, 90.0 mg/mL, 10.0 %, 5.0 %, 2.5 %, 3.0 %, 4.0 %, 20.0 %, 8.0 %, 3.5 %, 2.6 %, 0.0025 mg/mg, 0.026 mg/mg, 3.7 %, 0.035 mg/mg, 0.1467 mg/mg, 0.03 mg/mg, 0.0587 mg/mg, 52.5 mg/mL, 0.0375 mg/mg, 0.14 mg/mg, 0.15 mg/mg, 45.0 mg/mL, 0.0001 mg/mg, 0.045 mg/mL, 40.0 mg/mL, 200.0 mg/mL, 0.2 mg/mg, 85.0 mg/mL, 0.063 mg/mL, 0.283 mg/mg, 500.0 mg/mL, 60.0 mg, 0.085 mg/mg, 0.0275 mg/mg, 70000.0 mg/mL, 2.5 mg/mL, 0.102 mg/mg, 115.0 mg/mL, 36.9 mg/mL, 0.069 mg/mg, 65.0 mg/mL, 57.5 mg/mL, 0.068 mg/mg, 0.35 mg/mg, 0.5 mg/mg, 0.037 mL/mL, 25000.0 mg/mL, 50000.0 mg/mL, 0.0005 mg/mg, 0.136 mg/mg, 0.1173 mg/mg, 0.085 mg/mL, 0.0948 mg/mg, 0.0625 mg/mg, 9.8 mg/mg, 0.28 mg/mg, 0.075 mg/mL, 0.13 mg/mg, 75.0 mg/mL, 0.125 mg/mg, 0.0025 %/mg, 125.0 mg/mL, 62.0 mg/mL, 50.0 mg
, Lotion, Topical, Lotion - Topical, Kit, Gel, Gel - Topical, Liquid, Liquid - Topical, Cream, Cream - Topical, Solution, Solution - Topical, Swab, Swab - Topical, Aerosol, foam, Aerosol, foam - Topical, Cloth, Cloth - Topical, Emulsion, Emulsion - Topical, Soap, Soap - Topical, Liquid, extended release, Liquid, extended release - Topical, Kit - Topical, Ointment, Ointment - Topical, Suspension, Suspension - Topical, Gel; Lotion, Gel; Lotion - Topical, Paste, Paste - Topical, Jelly, Jelly - Topical, Kit; Lotion; Solution - Topical, Kit; Lotion; Solution, Cream; Gel; Kit; Lotion, Cream; Gel; Kit; Lotion - Topical, Kit; Lotion, Kit; Lotion - Topical, Aerosol, Aerosol - Topical, Gel; Kit; Lotion, Gel; Kit; Lotion - Topical, Gel; Kit, Gel; Kit - Topical, Kit; Liquid; Lotion, Kit; Liquid; Lotion - Topical, Stick - Topical, Stick, Shampoo, suspension, Shampoo, suspension - Topical, Gel; Kit; Paste - Topical, Gel; Kit; Paste, Cream; Kit; Lotion - Topical, Cream; Kit; Lotion, Lotion / shampoo, Lotion / shampoo - Topical, Transdermal, Lotion - Transdermal, Oil - Topical, Oil
Inflammation
0.025 mg/mg, , 0.05 mg/mg, 0.1 mg/mg, 25.0 mg/mL, 0.034 mg/mg, 0.0425 mg/mg, 26.0 mg/mL, 50.0 mg/mL, 0.007 mg/mg, 0.05 mg/mL, 0.1 mg/mL, 100.0 mg/mL, 0.005 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 10.0 mg/mL, 25.0 mg, 37.0 mg/mL, 2.75 mg, 0.025 mg/mL, 0.000085 mg/mg, 0.07 mg/mL, 0.06 mg/mg, 0.25 mg/mL, 0.025 mL/mL, 0.053 mg/mg, 0.098 mg/mg, 0.8 mg/mg, 70.0 mg/mL, 0.295 mL/mL, 0.0104 mg/mg, 0.08 mg/mg, 0.05 mL/mL, 0.001 mg/mg, 0.032 mg/mg, 0.09 mg/mg, 0.04 mg/mg, 0.055 mg/mg, 0.318 mg/mg, 0.07 mg/mg, 44.0 mg/mL, 55.0 mg/mL, 0.0525 mg/mg, 42.5 mg/mL, 0.135 mg/mg, 0.22 mg/mL, 0.1 mL/mL, 0.1125 mg/mg, 0.6 mg/mg, 5650.0 mg, 11300.0 mg, 35.0 mg/mL, 0.095 mg/mg, 0.00557 mg/mg, 61.62 mg/mL, 0.329 mg/mg, 30.0 mg/mL, 0.519 mg/mL, 0.3 mL/mL, 0.56 mg/mg, 0.075 mL/mL, 60.0 mg/mL, 90.0 mg/mL, 10.0 %, 5.0 %, 2.5 %, 3.0 %, 4.0 %, 20.0 %, 8.0 %, 3.5 %, 2.6 %, 0.0025 mg/mg, 0.026 mg/mg, 3.7 %, 0.035 mg/mg, 0.1467 mg/mg, 0.03 mg/mg, 0.0587 mg/mg, 52.5 mg/mL, 0.0375 mg/mg, 0.14 mg/mg, 0.15 mg/mg, 45.0 mg/mL, 0.0001 mg/mg, 0.045 mg/mL, 40.0 mg/mL, 200.0 mg/mL, 0.2 mg/mg, 85.0 mg/mL, 0.063 mg/mL, 0.283 mg/mg, 500.0 mg/mL, 60.0 mg, 0.085 mg/mg, 0.0275 mg/mg, 70000.0 mg/mL, 2.5 mg/mL, 0.102 mg/mg, 115.0 mg/mL, 36.9 mg/mL, 0.069 mg/mg, 65.0 mg/mL, 57.5 mg/mL, 0.068 mg/mg, 0.35 mg/mg, 0.5 mg/mg, 0.037 mL/mL, 25000.0 mg/mL, 50000.0 mg/mL, 0.0005 mg/mg, 0.136 mg/mg, 0.1173 mg/mg, 0.085 mg/mL, 0.0948 mg/mg, 0.0625 mg/mg, 9.8 mg/mg, 0.28 mg/mg, 0.075 mg/mL, 0.13 mg/mg, 75.0 mg/mL, 0.125 mg/mg, 0.0025 %/mg, 125.0 mg/mL, 62.0 mg/mL, 50.0 mg
, Lotion, Topical, Lotion - Topical, Kit, Gel, Gel - Topical, Liquid, Liquid - Topical, Cream, Cream - Topical, Solution, Solution - Topical, Swab, Swab - Topical, Aerosol, foam, Aerosol, foam - Topical, Cloth, Cloth - Topical, Emulsion, Emulsion - Topical, Soap, Soap - Topical, Liquid, extended release, Liquid, extended release - Topical, Kit - Topical, Ointment, Ointment - Topical, Suspension, Suspension - Topical, Gel; Lotion, Gel; Lotion - Topical, Paste, Paste - Topical, Jelly, Jelly - Topical, Kit; Lotion; Solution - Topical, Kit; Lotion; Solution, Cream; Gel; Kit; Lotion, Cream; Gel; Kit; Lotion - Topical, Kit; Lotion, Kit; Lotion - Topical, Aerosol, Aerosol - Topical, Gel; Kit; Lotion, Gel; Kit; Lotion - Topical, Gel; Kit, Gel; Kit - Topical, Kit; Liquid; Lotion, Kit; Liquid; Lotion - Topical, Stick - Topical, Stick, Shampoo, suspension, Shampoo, suspension - Topical, Gel; Kit; Paste - Topical, Gel; Kit; Paste, Cream; Kit; Lotion - Topical, Cream; Kit; Lotion, Lotion / shampoo, Lotion / shampoo - Topical, Transdermal, Lotion - Transdermal, Oil - Topical, Oil
Acne Vulgaris
0.025 mg/mg, , 0.05 mg/mg, 0.1 mg/mg, 25.0 mg/mL, 0.034 mg/mg, 0.0425 mg/mg, 26.0 mg/mL, 50.0 mg/mL, 0.007 mg/mg, 0.05 mg/mL, 0.1 mg/mL, 100.0 mg/mL, 0.005 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 10.0 mg/mL, 25.0 mg, 37.0 mg/mL, 2.75 mg, 0.025 mg/mL, 0.000085 mg/mg, 0.07 mg/mL, 0.06 mg/mg, 0.25 mg/mL, 0.025 mL/mL, 0.053 mg/mg, 0.098 mg/mg, 0.8 mg/mg, 70.0 mg/mL, 0.295 mL/mL, 0.0104 mg/mg, 0.08 mg/mg, 0.05 mL/mL, 0.001 mg/mg, 0.032 mg/mg, 0.09 mg/mg, 0.04 mg/mg, 0.055 mg/mg, 0.318 mg/mg, 0.07 mg/mg, 44.0 mg/mL, 55.0 mg/mL, 0.0525 mg/mg, 42.5 mg/mL, 0.135 mg/mg, 0.22 mg/mL, 0.1 mL/mL, 0.1125 mg/mg, 0.6 mg/mg, 5650.0 mg, 11300.0 mg, 35.0 mg/mL, 0.095 mg/mg, 0.00557 mg/mg, 61.62 mg/mL, 0.329 mg/mg, 30.0 mg/mL, 0.519 mg/mL, 0.3 mL/mL, 0.56 mg/mg, 0.075 mL/mL, 60.0 mg/mL, 90.0 mg/mL, 10.0 %, 5.0 %, 2.5 %, 3.0 %, 4.0 %, 20.0 %, 8.0 %, 3.5 %, 2.6 %, 0.0025 mg/mg, 0.026 mg/mg, 3.7 %, 0.035 mg/mg, 0.1467 mg/mg, 0.03 mg/mg, 0.0587 mg/mg, 52.5 mg/mL, 0.0375 mg/mg, 0.14 mg/mg, 0.15 mg/mg, 45.0 mg/mL, 0.0001 mg/mg, 0.045 mg/mL, 40.0 mg/mL, 200.0 mg/mL, 0.2 mg/mg, 85.0 mg/mL, 0.063 mg/mL, 0.283 mg/mg, 500.0 mg/mL, 60.0 mg, 0.085 mg/mg, 0.0275 mg/mg, 70000.0 mg/mL, 2.5 mg/mL, 0.102 mg/mg, 115.0 mg/mL, 36.9 mg/mL, 0.069 mg/mg, 65.0 mg/mL, 57.5 mg/mL, 0.068 mg/mg, 0.35 mg/mg, 0.5 mg/mg, 0.037 mL/mL, 25000.0 mg/mL, 50000.0 mg/mL, 0.0005 mg/mg, 0.136 mg/mg, 0.1173 mg/mg, 0.085 mg/mL, 0.0948 mg/mg, 0.0625 mg/mg, 9.8 mg/mg, 0.28 mg/mg, 0.075 mg/mL, 0.13 mg/mg, 75.0 mg/mL, 0.125 mg/mg, 0.0025 %/mg, 125.0 mg/mL, 62.0 mg/mL, 50.0 mg
, Lotion, Topical, Lotion - Topical, Kit, Gel, Gel - Topical, Liquid, Liquid - Topical, Cream, Cream - Topical, Solution, Solution - Topical, Swab, Swab - Topical, Aerosol, foam, Aerosol, foam - Topical, Cloth, Cloth - Topical, Emulsion, Emulsion - Topical, Soap, Soap - Topical, Liquid, extended release, Liquid, extended release - Topical, Kit - Topical, Ointment, Ointment - Topical, Suspension, Suspension - Topical, Gel; Lotion, Gel; Lotion - Topical, Paste, Paste - Topical, Jelly, Jelly - Topical, Kit; Lotion; Solution - Topical, Kit; Lotion; Solution, Cream; Gel; Kit; Lotion, Cream; Gel; Kit; Lotion - Topical, Kit; Lotion, Kit; Lotion - Topical, Aerosol, Aerosol - Topical, Gel; Kit; Lotion, Gel; Kit; Lotion - Topical, Gel; Kit, Gel; Kit - Topical, Kit; Liquid; Lotion, Kit; Liquid; Lotion - Topical, Stick - Topical, Stick, Shampoo, suspension, Shampoo, suspension - Topical, Gel; Kit; Paste - Topical, Gel; Kit; Paste, Cream; Kit; Lotion - Topical, Cream; Kit; Lotion, Lotion / shampoo, Lotion / shampoo - Topical, Transdermal, Lotion - Transdermal, Oil - Topical, Oil
Warnings
Clindamycin Phosphate and Benzoyl Peroxide has six contraindications, hence it should not be taken concurrently with the conditions outlined in the following table.Clindamycin Phosphate And Benzoyl Peroxide ContraindicationsCondition
Risk Level
Notes
Crohn Disease
Do Not Combine
History of Antibiotics Associated Colitis
Do Not Combine
pseudomembranous colitis
Do Not Combine
Colitis, Ulcerative
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Benzoyl Peroxide may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Benzoyl Peroxide may interact with Pulse Frequency
Common Clindamycin Phosphate And Benzoyl Peroxide Drug Interactions
Drug Name
Risk Level
Description
Dapsone
Minor
The risk or severity of adverse effects can be increased when Benzoyl peroxide is combined with Dapsone.
Clindamycin Phosphate And Benzoyl Peroxide Toxicity & Overdose RiskThere is a lack of information regarding overdoses of benzoyl peroxide. However, people who overdose may experience heightened symptoms such as skin irritation, burning, peeling, swelling, and redness. The lowest toxic dose of benzoyl peroxide in rats is 490mg/kg.
Clindamycin Phosphate And Benzoyl Peroxide Novel Uses: Which Conditions Have a Clinical Trial Featuring Clindamycin Phosphate And Benzoyl Peroxide?
There are 23 active clinical trials assessing the potential of Clindamycin Phosphate and Benzoyl Peroxide to ameliorate Inflammatory Acne Vulgaris, Acne and Acneiform lesions.Condition
Clinical Trials
Trial Phases
Acne Vulgaris
12 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Inflammation
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Clindamycin Phosphate And Benzoyl Peroxide Reviews: What are patients saying about Clindamycin Phosphate And Benzoyl Peroxide?
5Patient Review
7/20/2021 I had moderate acne that this treatment quickly helped clear up. Within a week, my skin was almost completely free of blemishes and hyperpigmentation. The only downside is that it can dry out your skin; however, using a quality moisturizer should fix that problem.
5Patient Review
11/16/2014 My skin is much clearer after using this product for just one month!
4.7Patient Review
1/7/2021 This treatment works well, but I have experienced some skin peeling and burning.
4.7Patient Review
5/20/2016 Will continue to work as long as you keep using it. I stopped for a week and only used it for spot treatments because it was making my face dry when applied all over, but this led to the product no longer preventing acne. In conclusion: use regularly for best results and consider using a lotion if you experience dry skin.
1.7Patient Review
8/20/2020 I had an allergic reaction to this medication that manifested as a rash and swelling of my face and throat. Over the counter allergy medicine was not effective in alleviating these symptoms.
1Patient Review
3/21/2022 My acne got worse after starting this treatment, and pus started to form all over my face.
Patient Q&A Section about clindamycin phosphate and benzoyl peroxide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is clindamycin phosphate and benzoyl peroxide used for?
"benzoyl peroxide and clindamycin combination is a topical medication used to treat acne vulgaris. The medication works by47 killing Propionibacterium acnes bacteria and keeping the skin pores clean. This medication is available only with a doctor's prescription."
Answered by AI
How long does it take for clindamycin phosphate and benzoyl peroxide to work?
"You may not see any improvement in your acne for up to 6 weeks, and it could take as long as 12 weeks to see the full benefit of the medication. If your acne doesn't improve or gets worse, tell your doctor."
Answered by AI
Is it okay to use a benzoyl peroxide product with clindamycin phosphate?
"Benzoyl peroxide products and clindamycin products should not be used by people who are allergic to clindamycin or benzoyl peroxide, or any other ingredient in the products."
Answered by AI
Do I Apply benzoyl peroxide first or clindamycin phosphate first?
"Apply the clindamycin solution first and then the benzoyl peroxide gel as directed by your doctor or pharmacist. Wash your hands after each use. Follow the instructions provided with these medications."
Answered by AI