Fansidar

Malaria, Malaria, Whom no Comparable or Satisfactory Alternative Therapy is Available + 2 more

Treatment

0 Active Studies for Fansidar

What is Fansidar

Sulfadoxine

The Generic name of this drug

Treatment Summary

Pyrimethamine is a medication used to treat malaria and toxoplasmosis. It works by blocking the action of folic acid, which is necessary for the growth of certain parasites. Pyrimethamine is typically used in combination with a sulfonamide to treat toxoplasmosis.

Fansidar

is the brand name

Fansidar Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Fansidar

Sulfadoxine

1981

1

Effectiveness

How Fansidar Affects Patients

Pyrimethamine is an antiparasitic drug used to treat malaria. It works by blocking the growth of malaria parasites and Toxoplasma gondii, a type of parasite that uses folic acid. It can destroy the parasites that cause malaria, but does not kill the gametocytes, or the cells that help the parasite spread to other people. When taken with other drugs, such as sulfonamides, it becomes more effective.

How Fansidar works in the body

Pyrimethamine stops the growth of malaria-causing parasites by blocking their ability to make DNA. By doing so, it prevents the parasites from multiplying and invading more cells in the body.

When to interrupt dosage

The proposed dosage of Fansidar relies upon the diagnosed state. The measure of dosage is contingent upon the method of administration specified in the table beneath.

Condition

Dosage

Administration

Whom no Comparable or Satisfactory Alternative Therapy is Available

500.0 mg,

, Tablet - Oral, Oral, Tablet

Malaria

500.0 mg,

, Tablet - Oral, Oral, Tablet

Malaria

500.0 mg,

, Tablet - Oral, Oral, Tablet

Malaria

500.0 mg,

, Tablet - Oral, Oral, Tablet

Chloroquine resistance

500.0 mg,

, Tablet - Oral, Oral, Tablet

Warnings

Fansidar Contraindications

Condition

Risk Level

Notes

repeated prophylactic use in blood dyscrasias

Do Not Combine

Anemia, Megaloblastic

Do Not Combine

Pulse Frequency

Do Not Combine

Alcohol or Other Drugs use

Do Not Combine

prophylactic use in pregnancy at term

Do Not Combine

Kidney Failure

Do Not Combine

Liver Failure

Do Not Combine

There are 20 known major drug interactions with Fansidar.

Common Fansidar Drug Interactions

Drug Name

Risk Level

Description

Acepromazine

Major

The risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Acepromazine.

Aceprometazine

Major

The risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Aceprometazine.

Acetophenazine

Major

The risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Acetophenazine.

Alimemazine

Major

The risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Alimemazine.

Artemether

Major

The risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Artemether.

image of a doctor in a lab doing drug, clinical research

Fansidar Novel Uses: Which Conditions Have a Clinical Trial Featuring Fansidar?

A single clinical trial is in progress to assess the capacity of Fansidar to mitigate Toxoplasmosis.

Condition

Clinical Trials

Trial Phases

Malaria

0 Actively Recruiting

Whom no Comparable or Satisfactory Alternative Therapy is Available

0 Actively Recruiting

Chloroquine resistance

0 Actively Recruiting

Malaria

0 Actively Recruiting

Malaria

0 Actively Recruiting

Fansidar Reviews: What are patients saying about Fansidar?

5

Patient Review

5/22/2010

Fansidar for Malaria

I unfortunately had a negative reaction to this drug and broke out in a rash a few days after taking it. My face was swollen and I had tiny bumps and intense itching on my face and torso for several days.

2.7

Patient Review

4/14/2008

Fansidar for Malaria

1

Patient Review

11/13/2009

Fansidar for Prevention of Falciparum Malaria that is Resistant to Chloroquine

My partner died after only three weeks of taking this medication. He developed TEN (toxic epidermal necrolysis) and his doctor failed to take him off the drug even after he reported a skin rash. Do not use this medication.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about fansidar

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who should not take Fansidar?

"Fansidar should be used with caution in patients with impaired renal or hepatic function, those with possible folate deficiency, and those with severe allergies or bronchial asthma. Some sulfonamide drugs can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency."

Answered by AI

When should I take Fansidar?

"The first dose of Fansidar should be taken 1 or 2 days before travel to an area where the disease is present. Take the medicine during your stay and for 4 to 6 weeks after returning home."

Answered by AI

What is the drug Fansidar used for?

"Fansidar is an antiparasitic drug used to treat malaria. The active ingredients in Fansidar are sulfadoxine and pyrimethamine. Fansidar is available in generic form."

Answered by AI