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What is Fluphenazine Decanoate
FluphenazineThe Generic name of this drug
Treatment SummaryThorazine is a psychiatric medication used for treating psychosis. It works in a similar way to chlorpromazine and is used to control symptoms including hallucinations and delusions.
Fluphenazine Hydrochlorideis the brand name
Fluphenazine Decanoate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fluphenazine Hydrochloride
Fluphenazine
1987
181
Approved as Treatment by the FDA
Fluphenazine, also known as Fluphenazine Hydrochloride, is approved by the FDA for 1 uses including Schizophrenia .Schizophrenia
Helps manage Psychosis
Effectiveness
How Fluphenazine Decanoate Affects PatientsFluphenazine is a drug used to treat schizophrenia and other mental illnesses. It has not been proven to help with behavior issues in people with intellectual disabilities.
How Fluphenazine Decanoate works in the bodyFluphenazine affects dopamine receptors in the brain to reduce the production of hormones from the hypothalamus and pituitary gland. This can lead to changes in metabolism, body temperature, alertness, blood pressure, and vomiting.
When to interrupt dosage
The amount of Fluphenazine Decanoate is conditioned by the determined condition, for instance Schizophrenia, Gilles de la Tourette's Syndrome and Sedation therapy. The dosage fluctuates in accordance with the method of administration (e.g. Tablet, film coated - Oral or Intramuscular) specified in the following table.Condition
Dosage
Administration
Tourette Syndrome
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Depression
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Schizophrenia
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Sedation therapy
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Chorea
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Sedation
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Huntington Disease
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Warnings
Fluphenazine Decanoate has seven contraindications, so it should not be taken when experiencing the conditions outlined in the following table.Fluphenazine Decanoate ContraindicationsCondition
Risk Level
Notes
Brain Injuries
Do Not Combine
Disease
Do Not Combine
Liver Damage
Do Not Combine
Mental Depression
Do Not Combine
Hypnotics
Do Not Combine
Brain Injuries
Do Not Combine
Comatose
Do Not Combine
Common Fluphenazine Decanoate Drug Interactions
Drug Name
Risk Level
Description
Amisulpride
Major
Fluphenazine may increase the antipsychotic activities of Amisulpride.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Fluphenazine.
Azelastine
Major
Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Fluphenazine.
Deutetrabenazine
Major
The risk or severity of adverse effects can be increased when Fluphenazine is combined with Deutetrabenazine.
Fluphenazine Decanoate Novel Uses: Which Conditions Have a Clinical Trial Featuring Fluphenazine Decanoate?
640 active investigations are examining the potential of Fluphenazine Decanoate to alleviate Huntington Disease, Sedation therapy and Choreiform movements.Condition
Clinical Trials
Trial Phases
Sedation therapy
0 Actively Recruiting
Sedation
1 Actively Recruiting
Phase 3
Tourette Syndrome
0 Actively Recruiting
Depression
365 Actively Recruiting
Phase 1, Phase 2, Early Phase 1, Not Applicable, Phase 4, Phase 3
Huntington Disease
11 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable
Chorea
0 Actively Recruiting
Schizophrenia
38 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Fluphenazine Decanoate Reviews: What are patients saying about Fluphenazine Decanoate?
5Patient Review
7/2/2015 I was on other medication for three years without any success, so you can imagine my relief when this drug actually worked. The voices I had been hearing were gone overnight.
4.3Patient Review
9/26/2009 This treatment was effective and I'm now back to feeling normal. Thank you!
4Patient Review
3/7/20083.7Patient Review
8/21/2011 This medication has been used to treat elderly patients for many years. Some oral movements are controlled with other meds; however, the patient has been able to live a good life with no admissions for relapse. F/U visits q 3mo with a psychiatrist is important as well as lab work.
1Patient Review
12/7/2016 I was extremely disappointed with this product. Not only did the injection hurt, but I also got an infection and lost my arm as a result. Do not buy this!
1Patient Review
2/9/2021 I experienced sexual dysfunction while taking this medication.
Patient Q&A Section about fluphenazine decanoate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How is fluphenazine decanoate administered?
"Fluphenazine decanoate is a medication that is typically injected deep into the muscle in the buttock area. Most patients stay within the dosage range of 12.5 mg to 100 mg, given at intervals of two to five weeks."
Answered by AI
What are the side effects of fluphenazine?
"Possible side effects include drowsiness, lethargy, dizziness, nausea, loss of appetite, sweating, dry mouth, blurred vision, headache, and constipation. Let your doctor know if any of these effects are severe or don't go away."
Answered by AI
What is another name for fluphenazine decanoate?
"Fluphenazine is a drug used to treat symptoms of schizophrenia. It is available under different brand names, including Modecate, Modecate Concentrate, Moditen, Prolixin (discontinued brand), and RhoFluphenazine."
Answered by AI
What is fluphenazine decanoate used for?
"The medication Fluphenazine decanoate belongs to the family of antipsychotics, more specifically the phenothiazines. It is used to treat schizophrenia and is thought to work by reducing dopamine in certain areas of the brain."
Answered by AI