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What is Fesoterodine Fumarate
FesoterodineThe Generic name of this drug
Treatment SummaryFesoterodine is a medication used to treat the symptoms of an overactive bladder, such as frequent urination and urge urinary incontinence.
Toviazis the brand name
Fesoterodine Fumarate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Toviaz
Fesoterodine
2008
29
Effectiveness
How Fesoterodine Fumarate Affects PatientsFesoteridine is broken down into 5-hydroxymethyl tolterodine (5-HMT) by the body. 5-HMT has the effect of blocking certain receptors (muscarinic) that cause increased bladder contractions and salivation. This reduces the pressure in the bladder and the urge to urinate.
How Fesoterodine Fumarate works in the bodyFesoterodine stops the muscles in your bladder from contracting. This reduces pressure in the bladder and limits how much can be emptied at once.
When to interrupt dosage
The proposed dose of Fesoterodine Fumarate is contingent upon the diagnosed state. The measure of dosage fluctuates, relative to the technique of delivery (e.g. Tablet, extended release or Tablet, film coated, extended release) noted in the table below.Condition
Dosage
Administration
Overactive Bladder Syndrome
, 4.0 mg, 8.0 mg
, Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Neurogenic Detrusor Overactivity
, 4.0 mg, 8.0 mg
, Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Obesity
, 4.0 mg, 8.0 mg
, Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Warnings
Fesoterodine Fumarate has four contraindications, so it should not be used when any of the conditions in the table below are present.Fesoterodine Fumarate ContraindicationsCondition
Risk Level
Notes
uncontrolled narrow-angle glaucoma
Do Not Combine
Gastric Retention
Do Not Combine
Urinary Retention
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fesoterodine may interact with Pulse Frequency
Common Fesoterodine Fumarate Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Fesoterodine is combined with Aclidinium.
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Fesoterodine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Fesoterodine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Fesoterodine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Fesoterodine is combined with Cimetropium.
Fesoterodine Fumarate Toxicity & Overdose RiskTests have shown that it takes 681 milligrams per kilogram of body weight to be toxic to rats when taken orally, and 316 milligrams per kilogram of body weight to be toxic to mice when taken orally. For rats and mice, 10 milligrams per kilogram of body weight is the highest dose tested without any observed adverse effects when taken intravenously.
Fesoterodine Fumarate Novel Uses: Which Conditions Have a Clinical Trial Featuring Fesoterodine Fumarate?
32 active trials are being conducted to assess the capacity of Fesoterodine Fumarate to alleviate symptoms of Overactive Bladder Syndrome.Condition
Clinical Trials
Trial Phases
Neurogenic Detrusor Overactivity
3 Actively Recruiting
Phase 2, Phase 3, Phase 1
Obesity
1 Actively Recruiting
Phase 2
Overactive Bladder Syndrome
33 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2
Fesoterodine Fumarate Reviews: What are patients saying about Fesoterodine Fumarate?
5Patient Review
5/4/2020 The Myrbetriq 25mg in concert with the 4mg Toviaz has been incredibly effective for me. No more leaks when coughing or squatting, and most importantly, no more dry mouth!
5Patient Review
5/4/2020 These two medications work great for me. I was using Toviaz 8mg before, but it made my mouth so dry that it was difficult to swallow. With these two drugs, I don't have any problems anymore.
5Patient Review
5/5/2017 Toviaz was great until I developed dry mouth and had to urinate more frequently. I was switched to a new medication.
5Patient Review
5/5/2017 Toviaz was working well for me until I developed dry mouth and had to urinate more frequently. My doctor put me on a new medication.
4Patient Review
2/20/2017 This treatment has helped me a lot. I have to be careful not to wait too long or I'll leakage, but it's still much better than what was happening before.
4Patient Review
2/20/2017 This treatment has been really helpful. I have to be careful not to wait too long between doses, or I'll start leaking again. 70% is a significant improvement from where I was before starting this medication.
3.3Patient Review
3/2/2019 I've been taking this treatment for a while now, and I'm sorry to say that I haven't seen much of a difference. The initial signs were good, but there hasn't been any significant change since then. Luckily, there haven't been any adverse side effects either.
3.3Patient Review
3/2/2019 I've been taking this medication for a while now, and I'm disappointed to say that I haven't seen much difference. Initially, there were some positive results, but they didn't last.
2.7Patient Review
7/16/2015 I've been taking this medication for four years now, and unfortunately I find that my incontinence has actually gotten worse. I'm often able to hold it during the day, but at night I'm up every two or three hours to use the bathroom.
2.7Patient Review
7/16/2015 I've been taking OXYBUTYN 5mg. 2x a day for 4 years URGE incontinence is worse in that I cannot make it to bathroom which is 10 feet from bedroom. I DO NOT understand why I am many times able to hold it in the daytime ( sometimes 3-5 hrs.) At night I am up at least every 2-3 hours
2.3Patient Review
8/15/2017 I've been on this medication for around six weeks, and during that time I have experienced significant hair loss. This has been really tough to deal with, especially because it's not just a little bit of shedding; I'm losing huge clumps of hair. If you're considering this treatment, be aware of the potential side effects.
2.3Patient Review
12/1/2017 I took one dose of this medication and had an absolutely terrible reaction. I couldn't urinate at all and ended up in the ER with a catheter. Not fun.
2.3Patient Review
3/22/2015 I had such a bad reaction to this medication. After just one dose I was in so much pain and throwing up. The pain continued all weekend long. This drug is terrible and I would rather deal with the other issue it's supposed to treat!
2.3Patient Review
5/6/2015 Made the situation worse.
2.3Patient Review
3/22/2015 Took only one dose and had such severe pain in my stomach that I was vomiting. The effects lasted all weekend, and I'd rather deal with frequent urination than go through that again.
2.3Patient Review
8/15/2017 I've been on this medication for six weeks and have experienced substantial hair loss. This has been really tough to deal with, especially since I'm also experiencing urinary pain. If you're considering this treatment, be aware of the potential side effects.
2.3Patient Review
5/10/2017 This medication caused my hair to fall out, which was really devastating. I had to stop taking it after only seven months.
2.3Patient Review
12/1/2017 This medication caused me a lot of trouble. I took one dose and then had to go to the emergency room because I couldn't urinate. They put in a catheter, and now I have to carry it around with me until my doctor's appointment.
2.3Patient Review
5/10/2017 I unfortunately had to stop taking this medication after seven months due to the intense hair loss I was experiencing on top of my head.
2.3Patient Review
5/6/2015 This medication made my condition significantly worse.
2Patient Review
6/10/2015 Toviaz was effective at first, but then I quickly returned to the same level of urgency and frequency as before taking it. This medication was prescribed because it supposedly doesn't have the same eye problems as Vesicare; however, that hasn't been my experience.
2Patient Review
6/10/2015 Toviaz was effective at first, but then stopped working well after six months. I'm back to square one. It was prescribed to me because it doesn't have the eye involvement of Vesicare; however, once again, having accidents and running to pee all the time.
1Patient Review
10/19/2018 Toviaz made me urinate more frequently than I ever have before. Sometimes I couldn't even empty my bladder, which just made the problem worse.
1Patient Review
11/2/2018 Unfortunately, this medication made my incontinence much worse. I was constantly leaking and found myself wetting myself multiple times a day.
1Patient Review
6/18/2020 I was only on this treatment for four days when I started having problems sleeping and urinating. Additionally, fluid began draining from my ears and eyes, and my skin started cracking open and oozing fluid. It was a nightmare!
1Patient Review
6/18/2020 I stopped taking this after only four days because I couldn't sleep and it made my urinary problems worse. Plus, fluid was draining from my ears and eyes, and my skin started cracking and oozing. It was a nightmare!
1Patient Review
11/2/2018 Unfortunately, this medication made my incontinence much worse. I was leaking and outright wetting myself several times a day.
1Patient Review
1/2/2020 About three weeks after I started taking this medication, I began experiencing debilitating stomach pain and vomiting. The kidney pain has been especially bad and just won't go away.
1Patient Review
1/2/2020 About three weeks after I started taking this medication, I began experiencing awful stomach pains and vomiting. Additionally, the pain in my kidneys has been unbearable and hasn't gone away.
1Patient Review
10/19/2018 I tried Toviaz 4 mg to help with my frequent urination, but all it did was make me have to go even more often. I would wake up every hour to use the restroom, and sometimes I couldn't even finish emptying my bladder. Don't bother with this medication; it will only make your situation worse.
Patient Q&A Section about fesoterodine fumarate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.When should I take fesoterodine?
"Extended-release fesoterodine is a tablet taken by mouth, typically once a day with or without food. It is generally taken at the same time each day."
Answered by AI
What are the side effects of the drug toviaz?
"The following text describes some of the possible side effects of a medication. If you experience any of these side effects, tell your doctor. To relieve dry mouth, suck on hard candy or ice chips, chew gum, drink water, or use a saliva substitute."
Answered by AI
What is the brand name for fesoterodine?
"Toviaz is a medication used to treat Overactive Bladder (OAB) symptoms, such as urinary incontinence, urinary urgency, and frequency."
Answered by AI
What is fesoterodine fumarate used for?
"Fesoterodine is a medication used to improve bladder function and relieve symptoms such as incontinence, urgency, and frequency in people with overactive bladder."
Answered by AI