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What is Micardis
TelmisartanThe Generic name of this drug
Treatment SummaryTelmisartan is a medication used to lower high blood pressure. It works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow. It is classified as an angiotensin II receptor blocker (ARB). Recent studies suggest that telmisartan may also help improve metabolism and have other beneficial effects.
Micardis HCTis the brand name
Micardis Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Micardis HCT
Telmisartan
2000
182
Approved as Treatment by the FDA
Telmisartan, also known as Micardis HCT, is approved by the FDA for 6 uses including unable to take ACE inhibitors and prophylaxis of cardiovascular event .unable to take ACE inhibitors
prophylaxis of cardiovascular event
Cardiovascular Events
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
no initial therapy
Used to treat no initial therapy in combination with Amlodipine
blood pressure inadequately controlled with monotherapy
Used to treat blood pressure inadequately controlled with monotherapy in combination with Amlodipine
Effectiveness
How Micardis Affects PatientsTelmisartan is a drug taken orally that stops angiotensin II, a hormone that increases blood pressure and affects the balance of water and sodium in the body, from working. It has the strongest connection to the angiotensin II receptor than other similar drugs, and has been found to have properties that can help with glucose and lipid metabolism, and reduce inflammation. Telmisartan works by preventing angiotensin II from causing the body to narrow blood vessels, release aldosterone, and increase the amount of sodium in the blood.
How Micardis works in the bodyTelmisartan blocks the action of angiotensin II, a hormone that causes blood vessels to constrict. This decreases the resistance of blood vessels, improving blood flow. Telmisartan does not affect other hormones or ion channels, but it may activate a receptor known as PPARγ. This can improve metabolism, helping to control diabetes without causing side effects.
When to interrupt dosage
The magnitude of Micardis is contingent upon the diagnosed disorder, such as an inability to take ACE inhibitors, Hypertensive disease and Diabetic Nephropathy. The amount of dosage is contingent upon the mode of delivery (e.g. Tablet - Oral or Tablet, multilayer) featured in the below table.Condition
Dosage
Administration
unable to take ACE inhibitors
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
prophylaxis of cardiovascular event
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Congestive Heart Failure
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Hypertensive disease
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Diabetic Nephropathies
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Cardiovascular Events
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
no initial therapy
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
blood pressure inadequately controlled with monotherapy
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Warnings
Micardis ContraindicationsCondition
Risk Level
Notes
Type 2 Diabetes
Do Not Combine
Common Micardis Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Telmisartan.
Amifostine
Major
Telmisartan may increase the hypotensive activities of Amifostine.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Telmisartan.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Telmisartan.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Telmisartan.
Micardis Toxicity & Overdose RiskThe lowest toxic dose of telmisartan in rats is 150-200 mg/kg in males and 200 to 250 mg/kg in females. There is no evidence of toxicity in rats or dogs when given 2000 mg/kg. Limited data is available on overdosage in humans, however likely symptoms include low blood pressure, dizziness, fast heartbeat, and slow heartbeat from overstimulation of the nervous system.
Micardis Novel Uses: Which Conditions Have a Clinical Trial Featuring Micardis?
328 active studies are in progress to gauge the potential of Micardis to improve blood pressure inadequately controlled with monotherapy, those unable to take ACE inhibitors and those with no initial therapy.Condition
Clinical Trials
Trial Phases
blood pressure inadequately controlled with monotherapy
0 Actively Recruiting
unable to take ACE inhibitors
0 Actively Recruiting
Congestive Heart Failure
190 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
prophylaxis of cardiovascular event
0 Actively Recruiting
Cardiovascular Events
4 Actively Recruiting
Not Applicable
no initial therapy
0 Actively Recruiting
Diabetic Nephropathies
0 Actively Recruiting
Hypertensive disease
21 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Micardis Reviews: What are patients saying about Micardis?
5Patient Review
11/7/2013 While this treatment is effective, it's not affordable for those on a fixed income. Additionally, the packaging is difficult to open and the tablet itself is quite sticky.
5Patient Review
5/11/2014 Even though my arms are still heavy and my back pain is bad, this treatment has helped me a lot.
4.7Patient Review
3/18/2017 I've been on this medication for four and a half years now, taking one eighty-milligram pill each day. It works well for me; my blood pressure usually runs between 130/120 and 80. The only downside is that I get tired more easily, but that's a fair tradeoff compared to alternatives like heart transplants (which my brother had to go through). If you're considering this medication, Boehringer Ingelheim offers a reduced price program that brings the monthly cost down to $35.35 per month.
4Patient Review
1/6/2014 I've been on this medication for a month to help with my blood pressure. Although it hasn't lowered my BP as much as I'd hoped, I have experienced other benefits like no muscle aches (though I take potassium pills too) and less fatigue. The only downside is that I've had a hacking cough, but based on what others have said, this may be a side effect of the medication.
3.7Patient Review
7/4/2014 My blood pressure has been spiking since my doctor told me to double my medication. I'm not sure if it's the heat or what, but it's been really frustrating.
3.7Patient Review
10/17/20133.7Patient Review
1/7/2014 The packaging of the individual tablets can be difficult to open.
3.3Patient Review
4/7/2014 I'm 59 years old and I was on Marcardis for about a month. I experienced almost half of the listed side effects, which were becoming increasingly severe. My blood pressure dropped to an alarmingly low level and my energy levels bottomed out, so I stopped taking the medication.
3.3Patient Review
5/23/2015 I've been taking Micardis for two months now, and I definitely prefer it to Nifedipine. I didn't have any of the side effects with Micardis that I did with Nifedipine (sleeplessness, trouble breathing), and Lisinopril was good too but I couldn't get it where I am. The only downside to Micardis is that the packaging is a pain to open.
3.3Patient Review
5/15/2014 No issues thus far, five days in.
3Patient Review
6/24/2014 I've been on this medication for over a decade now. It's effective and I don't really notice any negative side effects.
2.7Patient Review
12/25/2018 I was prescribed this for high blood pressure, but it only made my heart rate increase. I've also gained a lot of weight and become more clumsy over the past year. Despite increasing the dosage and adding amlodipine, my blood pressure hasn't changed much. I'm getting injured more frequently from falls, so I've decided to stop taking the medication.
2.7Patient Review
11/15/2018 This blister pack was very difficult to open, even compared to other similar products I've used in the past.
1.7Patient Review
3/31/2014 I tried this treatment for a month and while it did lower my blood pressure, the side effects were intolerable. I experienced dizziness, aches in my neck and shoulders, leg cramps, and eye strain. I've since switched to a different medication.
1.3Patient Review
1/1/2014 I've been on Micardis for over a decade now, and it's kept my blood pressure at a healthy level. I'm able to exercise regularly, and my heart rate is good. I also take Norvasc in the morning and evening.
Patient Q&A Section about micardis
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the side effect of Micardis?
"If you experience any of the following, call your doctor: swelling in your feet or ankles; rapid weight gain; unusual pain or tightness in your lower body; a skin ulcer; or a high potassium level. Symptoms of a high potassium level include nausea, weakness, tingly feeling, chest pain, irregular heartbeats, and loss of movement."
Answered by AI
Is Micardis a good blood pressure medicine?
"Telmisartan is an effective blood pressure-lowering medication that has beneficial effects on the heart and kidneys."
Answered by AI
What is the drug Micardis used for?
"This medication is used to lower high blood pressure in order to prevent strokes, heart attacks, and kidney problems. Telmisartan belongs to a class of drugs known as angiotensin receptor blockers (ARBs)."
Answered by AI
Which is better losartan or Micardis?
"Cozaar lowers blood pressure while simultaneously protecting kidney function, and has far fewer side effects than ACE inhibitors. Micardis lowers the risk of heart attack and stroke, and is similar to ACE inhibitors, but does not come with the same side effects, like coughing."
Answered by AI